Detalhe da pesquisa
1.
Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency.
EMBO J
; 41(4): e109108, 2022 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35019161
2.
Depletion and activation of microglia impact metabolic connectivity of the mouse brain.
J Neuroinflammation
; 20(1): 47, 2023 Feb 24.
Artigo
Inglês
| MEDLINE | ID: mdl-36829182
3.
The wide genetic landscape of clinical frontotemporal dementia: systematic combined sequencing of 121 consecutive subjects.
Genet Med
; 20(2): 240-249, 2018 02.
Artigo
Inglês
| MEDLINE | ID: mdl-28749476
4.
Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism.
EMBO Mol Med
; 11(6)2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31122931
5.
Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice.
Mol Neurodegener
; 13(1): 48, 2018 09 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30180904