Detalhe da pesquisa
1.
Ryanodine receptor remodeling in cardiomyopathy and muscular dystrophy caused by lamin A/C gene mutation.
Hum Mol Genet
; 29(24): 3919-3934, 2021 02 25.
Artigo
Inglês
| MEDLINE | ID: mdl-33388782
2.
Defective cerebellar ryanodine receptor type 1 and endoplasmic reticulum calcium 'leak' in tremor pathophysiology.
Acta Neuropathol
; 146(2): 301-318, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37335342
3.
Structure of a mammalian ryanodine receptor.
Nature
; 517(7532): 44-9, 2015 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25470061
4.
Late Ventilator-Induced Diaphragmatic Dysfunction After Extubation.
Crit Care Med
; 48(12): e1300-e1305, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33009102
5.
Intracellular calcium leak as a therapeutic target for RYR1-related myopathies.
Acta Neuropathol
; 139(6): 1089-1104, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32236737
6.
Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure.
Circulation
; 138(11): 1144-1154, 2018 09 11.
Artigo
Inglês
| MEDLINE | ID: mdl-29593014
7.
Leaky ryanodine receptors contribute to diaphragmatic weakness during mechanical ventilation.
Proc Natl Acad Sci U S A
; 113(32): 9069-74, 2016 08 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27457930
8.
Maintenance of normal blood pressure is dependent on IP3R1-mediated regulation of eNOS.
Proc Natl Acad Sci U S A
; 113(30): 8532-7, 2016 07 26.
Artigo
Inglês
| MEDLINE | ID: mdl-27402766
9.
Amyloid ß production is regulated by ß2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.
J Biol Chem
; 292(24): 10153-10168, 2017 06 16.
Artigo
Inglês
| MEDLINE | ID: mdl-28476886
10.
Mitochondrial calcium overload is a key determinant in heart failure.
Proc Natl Acad Sci U S A
; 112(36): 11389-94, 2015 Sep 08.
Artigo
Inglês
| MEDLINE | ID: mdl-26217001
11.
Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.
Acta Neuropathol
; 134(5): 749-767, 2017 11.
Artigo
Inglês
| MEDLINE | ID: mdl-28631094
12.
Genetically enhancing mitochondrial antioxidant activity improves muscle function in aging.
Proc Natl Acad Sci U S A
; 111(42): 15250-5, 2014 Oct 21.
Artigo
Inglês
| MEDLINE | ID: mdl-25288763
13.
Calcium leak through ryanodine receptors leads to atrial fibrillation in 3 mouse models of catecholaminergic polymorphic ventricular tachycardia.
Circ Res
; 111(6): 708-17, 2012 Aug 31.
Artigo
Inglês
| MEDLINE | ID: mdl-22828895
14.
Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion.
Proc Natl Acad Sci U S A
; 108(32): 13258-63, 2011 Aug 09.
Artigo
Inglês
| MEDLINE | ID: mdl-21788490
15.
Location of ryanodine receptor type 2 mutation predicts age of onset of sudden death in catecholaminergic polymorphic ventricular tachycardia - A systematic review and meta-analysis of case-based literature.
medRxiv
; 2024 Mar 16.
Artigo
Inglês
| MEDLINE | ID: mdl-38559077
16.
Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes.
FASEB J
; 26(3): 1009-17, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-22090316
17.
A novel ryanodine receptor mutation linked to sudden death increases sensitivity to cytosolic calcium.
Circ Res
; 109(3): 281-90, 2011 Jul 22.
Artigo
Inglês
| MEDLINE | ID: mdl-21659649
18.
Role of CaMKIIdelta phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure.
Proc Natl Acad Sci U S A
; 107(22): 10274-9, 2010 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20479242
19.
Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy.
Proc Natl Acad Sci U S A
; 107(4): 1559-64, 2010 Jan 26.
Artigo
Inglês
| MEDLINE | ID: mdl-20080623
20.
Heart failure-induced cognitive dysfunction is mediated by intracellular Ca2+ leak through ryanodine receptor type 2.
Nat Neurosci
; 26(8): 1365-1378, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37429912