Detalhe da pesquisa
1.
Triple Inhaled Therapy at Two Glucocorticoid Doses in Moderate-to-Very-Severe COPD.
N Engl J Med
; 383(1): 35-48, 2020 07 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32579807
2.
Treatment Trials in Young Patients with Chronic Obstructive Pulmonary Disease and Pre-Chronic Obstructive Pulmonary Disease Patients: Time to Move Forward.
Am J Respir Crit Care Med
; 205(3): 275-287, 2022 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34672872
3.
Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial.
Crit Care
; 26(1): 355, 2022 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36380312
4.
A randomized controlled trial of glycopyrrolate administered by metered dose inhaler in patients with uncontrolled asthma despite ICS/LABA treatment.
J Asthma
; 59(7): 1420-1432, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34338132
5.
Reduced All-Cause Mortality in the ETHOS Trial of Budesonide/Glycopyrrolate/Formoterol for Chronic Obstructive Pulmonary Disease. A Randomized, Double-Blind, Multicenter, Parallel-Group Study.
Am J Respir Crit Care Med
; 203(5): 553-564, 2021 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33252985
6.
Benefits of glycopyrrolate/formoterol fumarate metered dose inhaler (GFF MDI) in improving lung function and reducing exacerbations in patients with moderate-to-very severe COPD: a pooled analysis of the PINNACLE studies.
Respir Res
; 21(1): 128, 2020 May 25.
Artigo
Inglês
| MEDLINE | ID: mdl-32450869
7.
Determinants of Response to Roflumilast in Severe Chronic Obstructive Pulmonary Disease. Pooled Analysis of Two Randomized Trials.
Am J Respir Crit Care Med
; 198(10): 1268-1278, 2018 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29763572
8.
Effect of Aclidinium Bromide on Major Cardiovascular Events and Exacerbations in High-Risk Patients With Chronic Obstructive Pulmonary Disease: The ASCENT-COPD Randomized Clinical Trial.
JAMA
; 321(17): 1693-1701, 2019 05 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31063575
9.
A phase IIb randomized, chronic-dosing, incomplete block, cross-over study of glycopyrronium, delivered via metered dose inhaler, compared with a placebo and an active control in patients with moderate-to-severe COPD.
Respir Res
; 19(1): 38, 2018 03 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29506504
10.
Safety and pharmacokinetics of budesonide/glycopyrronium/formoterol fumarate dihydrate metered dose inhaler (BGF MDI) in healthy adult subjects of Japanese descent.
Pulm Pharmacol Ther
; 51: 18-25, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29763659
11.
The pharmacokinetics of three doses of budesonide/glycopyrronium/formoterol fumarate dihydrate metered dose inhaler compared with active controls: A Phase I randomized, single-dose, crossover study in healthy adults.
Pulm Pharmacol Ther
; 50: 11-18, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29544728
12.
Pharmacokinetics and safety of a single dose of the novel LAMA/LABA fixed-dose combination of glycopyrronium/formoterol fumarate dihydrate metered dose inhaler, formulated using co-suspension delivery technology, in Japanese healthy subjects.
Pulm Pharmacol Ther
; 53: 33-38, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30218695
13.
Cardiovascular safety profile of a fixed-dose combination of glycopyrrolate and formoterol fumarate delivered via metered dose inhaler using co-suspension delivery technology.
Pulm Pharmacol Ther
; 49: 67-74, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29567116
14.
Randomized dose-ranging study of a budesonide metered-dose inhaler by using co-suspension delivery technology in asthma.
Allergy Asthma Proc
; 39(5): 350-358, 2018 Sep 23.
Artigo
Inglês
| MEDLINE | ID: mdl-30037361
15.
A randomized, seven-day study to assess the efficacy and safety of a glycopyrrolate/formoterol fumarate fixed-dose combination metered dose inhaler using novel Co-Suspension™ Delivery Technology in patients with moderate-to-very severe chronic obstructive pulmonary disease.
Respir Res
; 18(1): 8, 2017 01 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28061907
16.
24-h bronchodilation and inspiratory capacity improvements with glycopyrrolate/formoterol fumarate via co-suspension delivery technology in COPD.
Respir Res
; 18(1): 157, 2017 08 18.
Artigo
Inglês
| MEDLINE | ID: mdl-28821260
17.
Effect of Roflumilast and Inhaled Corticosteroid/Long-Acting ß2-Agonist on Chronic Obstructive Pulmonary Disease Exacerbations (RE(2)SPOND). A Randomized Clinical Trial.
Am J Respir Crit Care Med
; 194(5): 559-67, 2016 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27585384
18.
Dose-response to inhaled glycopyrrolate delivered with a novel Co-Suspension™ Delivery Technology metered dose inhaler (MDI) in patients with moderate-to-severe COPD.
Respir Res
; 17(1): 109, 2016 09 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27586537
19.
Randomized study of the safety, pharmacokinetics, and bronchodilatory efficacy of a proprietary glycopyrronium metered-dose inhaler in study patients with chronic obstructive pulmonary disease.
BMC Pulm Med
; 14: 118, 2014 Jul 16.
Artigo
Inglês
| MEDLINE | ID: mdl-25027304
20.
Erratum to: A randomized, seven-day study to assess the efficacy and safety of a glycopyrrolate/formoterol fumarate fixed-dose combination metered dose inhaler using novel Co-Suspension™ Delivery Technology in patients with moderate-to-very severe chronic obstructive pulmonary disease.
Respir Res
; 18(1): 158, 2017 08 21.
Artigo
Inglês
| MEDLINE | ID: mdl-28826397