The Cell Tracking Challenge: 10 years of objective benchmarking.

The Cell Tracking Challenge is an ongoing benchmarking initiative that has become a reference in cell segmentation and tracking algorithm development. Here, we present a significant number of improvements introduced in the challenge since our 2017 report. These include the creation of a new segmentation-only benchmark, the enrichment of the dataset repository with new datasets that increase its diversity and complexity, and the creation of a silver standard reference corpus based on the most competitive results, which will be of particular interest for data-hungry deep learning-based strategies. Furthermore, we present the up-to-date cell segmentation and tracking leaderboards, an in-depth analysis of the relationship between the performance of the state-of-the-art methods and the properties of the datasets and annotations, and two novel, insightful studies about the generalizability and the reusability of top-performing methods. These studies provide critical practical conclusions for both developers and users of traditional and machine learning-based cell segmentation and tracking algorithms.

Entropic Out-of-Distribution Detection: Seamless Detection of Unknown Examples.

In this article, we argue that the unsatisfactory out-of-distribution (OOD) detection performance of neural networks is mainly due to the SoftMax loss anisotropy and propensity to produce low entropy probability distributions in disagreement with the principle of maximum entropy. On the one hand, current OOD detection approaches usually do not directly fix the SoftMax loss drawbacks, but rather build techniques to circumvent it. Unfortunately, those methods usually produce undesired side effects (e.g., classification accuracy drop, additional hyperparameters, slower inferences, and collecting extra data). On the other hand, we propose replacing SoftMax loss with a novel loss function that does not suffer from the mentioned weaknesses. The proposed IsoMax loss is isotropic (exclusively distance-based) and provides high entropy posterior probability distributions. Replacing the SoftMax loss by IsoMax loss requires no model or training changes. Additionally, the models trained with IsoMax loss produce as fast and energy-efficient inferences as those trained using SoftMax loss. Moreover, no classification accuracy drop is observed. The proposed method does not rely on outlier/background data, hyperparameter tuning, temperature calibration, feature extraction, metric learning, adversarial training, ensemble procedures, or generative models. Our experiments showed that IsoMax loss works as a seamless SoftMax loss drop-in replacement that significantly improves neural networks' OOD detection performance. Hence, it may be used as a baseline OOD detection approach to be combined with current or future OOD detection techniques to achieve even higher results.

Burst ranking for blind multi-image deblurring.

We propose a new incremental aggregation algorithm for multi-image deblurring with automatic image selection. The primary motivation is that current burst deblurring methods do not handle well situations in which misalignment or out-of-context frames are present in the burst. These real-life situations result in poor reconstructions or manual selection of the images that are used to deblur. Automatically selecting the best frames within the burst to improve the base reconstruction is challenging because the number of possible images fusions is equal to the power set cardinal. Here, we approach the multi-image deblurring problem as a two steps process. First, we successfully learn a comparison function to rank a burst of images using a deep convolutional neural network. Then, an incremental Fourier burst accumulation with a reconstruction degradation mechanism is applied fusing only less blurred images that are sufficient to maximize the reconstruction quality. Experiments with the proposed algorithm have shown superior results when compared to other similar approaches, outperforming other methods described in the literature in previously described situations. We validate our findings on several synthetic and real datasets.

Unsupervised Retinal Vessel Segmentation Using Combined Filters.

Image segmentation of retinal blood vessels is a process that can help to predict and diagnose cardiovascular related diseases, such as hypertension and diabetes, which are known to affect the retinal blood vessels' appearance. This work proposes an unsupervised method for the segmentation of retinal vessels images using a combined matched filter, Frangi's filter and Gabor Wavelet filter to enhance the images. The combination of these three filters in order to improve the segmentation is the main motivation of this work. We investigate two approaches to perform the filter combination: weighted mean and median ranking. Segmentation methods are tested after the vessel enhancement. Enhanced images with median ranking are segmented using a simple threshold criterion. Two segmentation procedures are applied when considering enhanced retinal images using the weighted mean approach. The first method is based on deformable models and the second uses fuzzy C-means for the image segmentation. The procedure is evaluated using two public image databases, Drive and Stare. The experimental results demonstrate that the proposed methods perform well for vessel segmentation in comparison with state-of-the-art methods.

Lateral inhibition pyramidal neural network for image classification.

The human visual system is one of the most fascinating and complex mechanisms of the central nervous system that enables our capacity to see. It is through the visual system that we are able to accomplish from the most simple task such as object recognition to the most complex visual interpretation, understanding and perception. Inspired by this sophisticated system, two models based on the properties of the human visual system are proposed. These models are designed based on the concepts of receptive and inhibitory fields. The first model is a pyramidal neural network with lateral inhibition, called lateral inhibition pyramidal neural network. The second proposed model is a supervised image segmentation system, called segmentation and classification based on receptive fields. This work shows that the combination of these two models is beneficial, and the results obtained are better than that of other state-of-the-art methods.

Computer-assisted coloring and illuminating based on a region-tree structure.

Colorization and illumination are key processes for creating animated cartoons. Computer assisted methods have been incorporated in animation/illustration systems to reduce the artists' workload. This paper presents a new method for illumination and colorization of 2D drawings based on a region- tree representation. Starting from a hand-drawn cartoon, the proposed method extracts geometric and topological information and builds a tree structure, ensuring independence among parts of the drawing, such as curves and regions. Based on this structure and its attributes, a colorization method that propagates through consecutive frames of animation is proposed, combined with an interpolation method that accurately computes a normal mapping for the illumination process. Different operators for curve and region attributes can be applied independently, obtaining different rendering effects.