RESUMO
Women with absolute uterine factor infertility cannot get pregnant. The current experience in uterine transplantation is limited and the use of a deceased donor uterus in this area is incipient after some initial unsuccessful attempts. The birth of healthy babies through this modality in four different centers has given a new impetus to the use of this transplantation technique. We aimed to develop a technique for uterus procurement and preparation for transplantation from a brain dead donor. Fifteen uteri were retrieved from multi-organ donor patients, 10 of these were used in bench surgeries with the proposed technique. All procedures were performed after obtaining family's consent. This study allowed the clinical use of two of the 15 organs that were procured for transplantation. One of these organs resulted in the first live birth worldwide using a uterus transplanted from a deceased donor, a landmark in reproductive medicine. Another outcome was the optimization of the surgical technique involving less manipulation of the uterine vascular pedicles. The success of this novel technique suggests that the proposed model can be replicated and optimized further to facilitate the transplantation of uterus from deceased donors.
Assuntos
Infertilidade Feminina , Morte Encefálica , Seleção do Doador , Feminino , Humanos , Gravidez , Doadores de Tecidos , ÚteroRESUMO
The bronze bug, Thaumastocoris peregrinus, an Australian native insect, has become a nearly worldwide invasive pest in the last 16 years and has been causing significant damage to eucalypts (Myrtaceae), including Eucalyptus spp. and Corymbia spp. Its rapid expansion leads to new questions about pathways and routes that T. peregrinus used to invade other continents and countries. We used mtDNA to characterize specimens of T. peregrinus collected from 10 countries where this species has become established, including six recently invaded countries: Chile, Israel, Mexico, Paraguay, Portugal, and the United States of America. We then combined our mtDNA data with previous data available from South Africa, Australia, and Europe to construct a world mtDNA network of haplotypes. Haplotype A was the most common present in all specimens of sites sampled in the New World, Europe, and Israel, however from Australia second more frequently. Haplotype D was the most common one from native populations in Australia. Haplotype A differs from the two major haplotypes found in South Africa (D and G), confirming that at least two independent invasions occurred, one from Australia to South Africa, and the other one from Australia to South America (A). In conclusion, Haplotype A has an invasion success over many countries in the World. Additionally, analyzing data from our work and previous reports, it is possible to suggest some invasive routes of T. peregrinus to predict such events and support preventive control measures.
Assuntos
Heterópteros/genética , Animais , Ásia , Austrália , DNA Mitocondrial/genética , Complexo IV da Cadeia de Transporte de Elétrons/química , Complexo IV da Cadeia de Transporte de Elétrons/genética , Europa (Continente) , Variação Genética , Haplótipos , Proteínas de Insetos/química , Proteínas de Insetos/genética , América do Norte , América do SulRESUMO
El alargamiento coronal es un procedimiento ampliamente usado en periodoncia, tanto para procedimientos estéticos como para procedimientos preprotésicos, y es una situación que se presenta con gran frecuenciaen la consulta diaria de periodoncia, por lo que es de vital importancia el conocimiento de las estructuras anatómicas del periodonto para realizar un buen procedimiento quirúrgico, precedido a un exhaustivo examen clínico y radiográfico y un acertado plan de tratamiento protésico. También es indispensable que el clínico conozca todas las técnicas quirúrgicas debido a que no todos los procedimientos requieren del mismo manejo y hay ciertas características anatómicas y quirúrgicas que se deben tener en cuenta al momento de planear una cirugía de alargamiento coronal. En este artículo presentamos un caso clínico en el que se integran la parte periodontal y la parte protésica...(AU)
used in periodontal practice, for esthetic procedures and also for pre-prosthetic ones; situation that is present with great frequency in the daily practice in periodontics. It is very important the knowledge of the anatomic structures of the periodontal anatomy in order to do a proper surgical procedure, preceded by a deep clinical and radiological exam and a pertinent treatment prosthetic plan. It is also important that the clinician knows all the surgical techniques, because not all the procedures need the same approach and there are certain anatomic and surgical characteristics that must be taken in concern at the moment of planning a surgical crown lengthening. In this article we present a clinical case where it is integrated the periodontal and prosthetic discipline...(AU)