Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 39
Filtrar
1.
J Soc Pers Relat ; 39(11): 3204-3227, 2022 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-36349312

RESUMO

The COVID-19 pandemic has touched many aspects of people's lives around the world, including their romantic relationships. While media outlets have reported that the pandemic is difficult for couples, empirical evidence is needed to test these claims and understand why this may be. In two highly powered studies (N = 3271) using repeated measure and longitudinal approaches, we found that people who experienced COVID-19 related challenges (i.e., lockdown, reduced face-to-face interactions, boredom, or worry) also reported greater self and partner phone use (Study 1) and time spent on social media (Study 2), and subsequently experienced more conflict and less satisfaction in their romantic relationship. The findings provide insight into the struggles people faced in their relationships during the pandemic and suggest that the increase in screen time - a rising phenomenon due to the migration of many parts of life online - may be a challenge for couples.

2.
Pediatr Res ; 86(5): 646-650, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-31291643

RESUMO

BACKGROUND: The aim of this study is to investigate free carnitine (C0) and total acylcarnitine levels (AC) in preterm infants with BW < 1800 g and the relationship with neonatal and perinatal factors. METHODS: Ninety-three thousand two hundred and ninety-three newborns were screened between 2011 and 2013. Dried blood samples (DBS) were collected at 48-72 h, 14, and 30 days of age. We studied 92 consecutive preterm (BW < 1800 g) infants with low carnitine levels at 30 days of life (Group 1). As controls, we included the first 92 cases (BW < 1800 g) with normal carnitine levels (Group 2) and another 92 at or near-term newborns with BW > 1800 g (Group 3). RESULTS: Compared to 48-72 h levels, C0 and AC decreased at 14 and 30 days of life in Groups 1 and 2 (p < 0.001). In Group 2, the percentage of children with carnitine-free parenteral nutrition (PN) and BW < 1000 g was lower than in Group 1 (p < 0.001). Only in Group 2 did C0 increase at 30 days (p < 0.001). The multivariate regression analysis confirmed the influence of body weight and type of nutrition on C0 and AC. CONCLUSION: Body weight and type of nutrition influenced the carnitine longitudinal pattern.


Assuntos
Peso ao Nascer , Carnitina/sangue , Recém-Nascido Prematuro/sangue , Estudos de Casos e Controles , Teste em Amostras de Sangue Seco , Humanos , Recém-Nascido , Estudos Longitudinais
3.
Psychol Sci ; 29(11): 1731-1741, 2018 11.
Artigo em Inglês | MEDLINE | ID: mdl-30226792

RESUMO

Growing evidence suggests that the seeds of relationship decay can be detected via implicit partner evaluations even when explicit evaluations fail to do so. However, little is known about the concrete daily relational processes that explain why these gut feelings are such important determinants of relationships' long-term outcomes. The present integrative multimethod research yielded a novel finding: that participants with more positive implicit partner evaluations exhibited more constructive nonverbal (but not verbal) behavior toward their partner in a videotaped dyadic interaction. In turn, this behavior was associated with greater satisfaction with the conversation and with the relationship in the following 8-day diary portion of the study. These findings represent a significant step forward in understanding the crucial role of automatic processes in romantic relationships. Together, they provide novel evidence that relationship success appears to be highly dependent on how people spontaneously behave in their relationship, which may be ultimately rooted in their implicit partner evaluations.


Assuntos
Relações Interpessoais , Comunicação não Verbal , Cônjuges/psicologia , Adolescente , Adulto , Feminino , Humanos , Masculino , Casamento/psicologia , Satisfação Pessoal , Autoimagem , Adulto Jovem
4.
Psychol Sci ; 28(3): 297-306, 2017 03.
Artigo em Inglês | MEDLINE | ID: mdl-28080302

RESUMO

Major forms of corruption constitute a strong threat to the functioning of societies. The most frequent explanation of how severe corruption emerges is the slippery-slope metaphor-the notion that corruption occurs gradually. While having widespread theoretical and intuitive appeal, this notion has barely been tested empirically. We used a recently developed paradigm to test whether severely corrupt acts happen gradually or abruptly. The results of four experimental studies revealed a higher likelihood of severe corruption when participants were directly given the opportunity to engage in it (abrupt) compared with when they had previously engaged in minor forms of corruption (gradual). Neither the size of the payoffs, which we kept constant, nor evaluations of the actions could account for these differences. Contrary to widely shared beliefs, sometimes the route to corruption leads over a steep cliff rather than a slippery slope.


Assuntos
Tomada de Decisões , Princípios Morais , Comportamento Social , Normas Sociais , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
5.
J Clin Microbiol ; 52(8): 2963-70, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24899036

RESUMO

The aim of this study was to assess the diagnostic value of IgM Western blotting (WB), IgA enzyme immunoassay (EIA), and DNA amplification by real-time PCR on Guthrie cards to retrospectively establish the diagnosis of congenital toxoplasmosis (CT). To this purpose, Guthrie cards were collected from 18 infants born to mothers with primary Toxoplasma gondii infection during pregnancy. Moreover, the analytical sensitivity of T. gondii PCR was assessed by testing mock dried blood specimens set up with several known DNA dilutions. IgM WB was demonstrated to be the most sensitive method. When the results of T. gondii DNA detection and specific IgM recovery were combined, retrospective CT diagnosis by using Guthrie cards was established in 3 out of 6 infected infants (sensitivity, 50%; 95% confidence interval, 26.8% to 73.2%). No positive PCR or serologic results were found in the group of 12 uninfected infants, demonstrating the excellent specificity of the three methods (95% confidence interval, 78.1% to 99.5%). The findings of the present study suggest that, in cases of missed diagnosis of CT at birth, analysis of Guthrie cards for children with compatible clinical findings after the perinatal period, in particular the combination of recovery of specific IgM antibodies and T. gondii DNA amplification, could be helpful. Nevertheless, since suboptimal conditions of storage of dried blood specimens can seriously affect sensitivity, negative results cannot rule out CT diagnosis. In contrast, because of the excellent specificity shown by IgM serologic testing and T. gondii DNA amplification on Guthrie cards, positive results obtained by either of the two methods should be considered diagnostic.


Assuntos
Técnicas de Diagnóstico Molecular/métodos , Toxoplasma/isolamento & purificação , Toxoplasmose Congênita/diagnóstico , Anticorpos Antiprotozoários/análise , Western Blotting , DNA de Protozoário/análise , Ensaio de Imunoadsorção Enzimática , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Reação em Cadeia da Polimerase , Gravidez , Sensibilidade e Especificidade , Testes Sorológicos , Toxoplasmose Congênita/parasitologia
6.
Emotion ; 24(5): 1190-1205, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-38300552

RESUMO

People often feel mixed and conflicting feelings (i.e., ambivalence) toward their romantic partner. So far, research has primarily shown that ambivalence is linked to negative outcomes in relationships, but is this always true? Building off the affect, behavior, cognition model of ambivalence, the present work tests the idea that, when ambivalent, individuals can experience both positive and negative cognitive and behavioral responses toward their partner. This idea was tested in three different studies with people in romantic relationships: a cross-sectional international study (n = 665), a 10-day daily diary study (n = 171), and a 12-day daily diary study with two follow-ups (n = 176 couples and nine individuals). Across studies, when people experienced greater subjective ambivalence (i.e., explicitly reported feeling mixed and conflicted) toward their partner, they spent more time thinking about the difficulties they faced in their relationship but also about ways in which they can make it better and, in turn, engaged in both constructive (e.g., wanting to spend more time with the partner) and destructive (e.g., ignoring or criticizing the partner) behaviors toward their partner. Ambivalence was also associated with greater fluctuations in both constructive and destructive behaviors daily and over time. This work advances the current knowledge about ambivalence in romantic relationships and further demonstrates that individuals can experience both positive and negative cognitions and behaviors toward a partner when ambivalent. (PsycInfo Database Record (c) 2024 APA, all rights reserved).


Assuntos
Emoções , Relações Interpessoais , Parceiros Sexuais , Humanos , Masculino , Feminino , Adulto , Parceiros Sexuais/psicologia , Estudos Transversais , Adulto Jovem , Pessoa de Meia-Idade , Adolescente , Conflito Psicológico
7.
J Clin Endocrinol Metab ; 109(2): e495-e507, 2024 Jan 18.
Artigo em Inglês | MEDLINE | ID: mdl-37820735

RESUMO

CONTEXT: In 2005, a nationwide program of iodine prophylaxis on a voluntary basis was implemented in Italy by law. However, recent data on iodine status are lacking. OBJECTIVE: The aim of this study was to evaluate efficiency, effectiveness, and possible adverse effects (increased occurrence of thyroid autoimmunity and hyperthyroidism) of the Italian iodine prophylaxis program. METHODS: From 2015 to 2019, a nationwide survey was performed. The use of iodized salt was evaluated in a sample of 164 593 adults and in 998 school canteens. A sample of 4233 schoolchildren (aged 11-13 years) was recruited to assess urinary iodine concentration, prevalence of goiter, and thyroid hypoechogenicity on ultrasound, with the latter being an indirect indicator of thyroid autoimmunity. Neonatal TSH values of 197 677 infants screened in regions representative of Northern, Central, and Southern Italy were analyzed to investigate the percentage of TSH values >5.0 mIU/L. Data on methimazole prescriptions were analyzed as indirect indicators of new cases of hyperthyroidism. RESULTS: The prevalence of the use of iodized salt was 71.5% in adult population and 78% in school canteens. A median urinary iodine concentration of 124 µg/L, a prevalence of goiter of 2.2%, and a prevalence of thyroid hypoechogenicity of 5.7% were observed in schoolchildren. The percentage of neonatal TSH values >5.0 mIU/L resulted still higher (5.1%) than the World Health Organization threshold of 3.0%, whereas the prescriptions of methimazole showed a reduction of 13.5%. CONCLUSION: Fifteen years of iodine prophylaxis have led to iodine sufficiency in Italy, although there still is concern about iodine nutritional status during pregnancy.


Assuntos
Bócio , Hipertireoidismo , Iodo , Adulto , Feminino , Lactente , Gravidez , Recém-Nascido , Humanos , Criança , Metimazol , Bócio/epidemiologia , Bócio/prevenção & controle , Cloreto de Sódio na Dieta , Itália/epidemiologia , Prevalência , Tireotropina
8.
Psychol Sci ; 24(8): 1533-40, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-23780725

RESUMO

Although previous theories and research have suggested that human behavior is automatically driven by selfish impulses (e.g., vengeance rather than forgiveness), the present research tested the hypothesis that in close relationships, people's impulsive inclination is to be prosocial and to sacrifice for their partner-to pursue the interests of the partner or of the relationship at some costs for the self. Results from four studies demonstrated that people with low self-control, relative to those with high self-control, reported greater willingness to sacrifice for their close others. Furthermore, Study 4 demonstrated that communal orientation was more strongly associated with sacrifice among participants with low self-control than participants with high self-control. This moderational pattern supports the hypothesis that communal orientation functions as a default approach to sacrifice in the context of close relationships. Taken together, these findings suggest that under certain crucial conditions in close relationships, gut-level impulses are more likely than deliberative considerations to promote prorelationship behavior.


Assuntos
Tomada de Decisões , Comportamento Impulsivo , Relações Interpessoais , Comportamento Social , Adolescente , Adulto , Feminino , Humanos , Masculino , Motivação , Adulto Jovem
9.
Children (Basel) ; 10(2)2023 Feb 17.
Artigo em Inglês | MEDLINE | ID: mdl-36832525

RESUMO

Cysthiatonine beta-synthase (CBS) deficiency (CBSD) is an autosomal recessive rare disorder caused by variations on CBS that leads to impaired conversion of homocysteine (Hcy) to cystathionine. Marked hyperhomocysteinemia is the hallmark of the disease. The administration of pyridoxine, the natural cofactor of CBS, may reduce total plasma Hcy. Patient phenotype is classified on pyridoxine responsivity in two groups: pyridoxine-responsive and non-responsive patients. Ectopia lentis, bone deformities, developmental delay, and thromboembolism are the classic signs and symptoms of the disease. Early diagnosis and treatment impact patients' natural history. Therapy aims to lower promptly and maintain Hcy concentrations below 100 µmol/L. Depending on the patient's phenotype, the treatment goals could be obtained by the administration of pyridoxine and/or betaine associated with a methionine-restricted diet. CBSD could be diagnosed in the early days of life by expanded newborn screening (ENS), however, the risk of false negative results is not negligible. In Emilia-Romagna (Italy), during the first 10 years of screening experience, only three cases of CBSD identified have been diagnosed, all in the last two years (incidence 1:118,000 live births). We present the cases and a comprehensive review of the literature to emphasize the role of ENS for early diagnosis of CBSD and its potential pitfalls, reiterating the need for a more effective method to screen for CBSD.

10.
Bioengineering (Basel) ; 10(6)2023 Jun 04.
Artigo em Inglês | MEDLINE | ID: mdl-37370617

RESUMO

The occupational risk of operators using display screen equipment (DSE) is usually evaluated according to the extent of time spent in active operator-DSE interactions. Risk assessment is based on activity data collected through questionnaires. We evaluated an original and innovative system that can objectively assess active operator-DSE interactions by collecting electrical impulses generated by the activation of mouse, keyboard and a camera that collects attentive eye-screen fixation. The main aim of this study was to evaluate the system's performance on an employee sample involved in the task of active reading and copying at a DSE workstation connected to the system. In the context of mandatory health surveillance at work, we enrolled 38 DSE operators with normal neuropsychological and eye assessments who were required to complete two predefined reading and writing tasks. The obtained results show that the system is able to collect activity data derived from operator-DSE interactions through screen fixation, keyboard tapping and mouse handling. In the copying task, the session duration as recorded by the system was highly related to the screen fixation time. In the copying task, mouse and keyboard activities were more strongly related to session duration than screen fixation. For the copying task, it was also possible to obtain individual profiles of operator-DSE interactions while performing the same standardized tasks. Collected data can allow an objective evaluation of active time spent by DSE operators at their workstations, thus allowing a more accurate occupational health risk assessment and management. Prospective analysis of individual operator-DSE interaction profiles can favor the setup of targeted preventive and organizational interventions from an of even wider worker wellbeing perspective.

11.
J Pers Soc Psychol ; 125(2): 367-396, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-36848105

RESUMO

Feeling loved (loved, cared for, accepted, valued, understood) is inherently dyadic, yet most prior theoretical perspectives and investigations have focused on how actors feeling (un)loved shapes actors' outcomes. Adopting a dyadic perspective, the present research tested whether the established links between actors feeling unloved and destructive (critical, hostile) behavior depended on partners' feelings of being loved. Does feeling loved need to be mutual to reduce destructive behavior, or can partners feeling loved compensate for actors feeling unloved? In five dyadic observational studies, couples were recorded discussing conflicts, diverging preferences or relationship strengths, or interacting with their child (total N = 842 couples; 1,965 interactions). Participants reported how much they felt loved during each interaction and independent coders rated how much each person exhibited destructive behavior. Significant Actors' × Partners' Felt-Loved interactions revealed a strong-link/mutual felt-unloved pattern: partners' high felt-loved buffered the damaging effect of actors' low felt-loved on destructive behavior, resulting in actors' destructive behavior mostly occurring when both actors' and partners' felt-loved was low. This dyadic pattern also emerged in three supplemental daily sampling studies. Providing directional support for the strong-link/mutual felt-unloved pattern, in Studies 4 and 5 involving two or more sequential interactions, Actors' × Partners' Felt-Loved in one interaction predicted actors' destructive behavior within couples' subsequent conflict interactions. The results illustrate the dyadic nature of feeling loved: Partners feeling loved can protect against actors feeling unloved in challenging interactions. Assessing Actor × Partner effects should be equally valuable for advancing understanding of other fundamentally dyadic relationship processes. (PsycInfo Database Record (c) 2023 APA, all rights reserved).


Assuntos
Emoções , Relações Interpessoais , Criança , Humanos , Hostilidade , Parceiros Sexuais
12.
J Exp Psychol Gen ; 151(10): 2511-2533, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-35298231

RESUMO

Evidence suggesting that implicit partner evaluations (IPEs), but not explicit evaluations (EPEs), can predict later changes in satisfaction and relationship status has led researchers to postulate that IPEs must be especially sensitive to relational reward and costs. However, supporting evidence for this assumption remains scarce, and very little is known regarding how IPEs versus EPEs actually update in everyday life. Two studies (one in-lab dyadic interaction study, N = 255, and one 14-day dyadic diary study, N = 348) investigated updating in IPEs and EPEs in the context of real-life relationship experiences. Study 1 revealed that the level of positive and negative experiences that a couple encountered while discussing a divergence of interests in their relationship predicted pre-to-post changes in EPEs, but not in IPEs. Study 2 revealed that IPEs showed less sensitivity to everyday relationship experiences across multiple metrics over the course of 14 days. Specifically, compared with EPEs, IPEs fluctuated less at the within- (vs. between-) person level, showed less-abrupt changes from day-to-day, and had a substantially weaker relationship with same-day positive and negative experiences. Rather than covarying with same-day experiences, IPEs appeared sensitive to relationship experiences aggregated across multiple prior days as well as to highly diagnostic relationship experiences, such as breakup. Consistent with recent advances in social-cognitive research, these findings support a modified account of IPE sensitivity, according to which IPEs show only gradual shifts under everyday circumstances, but more-dramatic shifts under highly diagnostic circumstances. Implications of these findings for close relationships and implicit social cognition research are discussed. (PsycInfo Database Record (c) 2022 APA, all rights reserved).


Assuntos
Relações Interpessoais , Satisfação Pessoal , Humanos , Acontecimentos que Mudam a Vida
13.
Curr Opin Psychol ; 44: 74-79, 2022 04.
Artigo em Inglês | MEDLINE | ID: mdl-34571369

RESUMO

Although previous research has found that prosocial behavior increases personal and relationship well-being, a particularly costly type of prosocial behavior - sacrifice - can sometimes have aversive effects and is the focus of the current review. We consider effects for both the individual who enacts the sacrifice and the recipient. Sacrifice, can take a toll on the giver's well-being, is a mixed blessing for the recipient (when they perceive the sacrifice), and may have some harmful consequences for relationships in the long-run. We discuss the importance of finding the right strategies (e.g. alternative solutions, comparison of costs and rewards between partners, reappraisals) to navigate these complex interpersonal situations in which partners' goals and preferences conflict.


Assuntos
Altruísmo , Relações Interpessoais , Afeto , Humanos
14.
Emotion ; 22(1): 81-99, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34990192

RESUMO

People in romantic relationships tend to have positive feelings toward their partner and want their relationship to last. However, maintaining a romantic relationship over time is challenging, and people can often experience mixed and conflicting feelings (i.e., ambivalence) toward their significant other. While research has identified the serious consequences that ambivalence can have for personal and relational well-being, very little is known about the factors that can lead people to experience ambivalence in relationships. The present work examines how extradyadic desire (i.e., desire for someone other than the partner), a common difficulty people face in the context of monogamy, is a situation in which people feel more ambivalent toward their partner. In three studies (N = 1,178) using experimental, daily diary, and longitudinal approaches, we find that feelings of desire for an attractive alternative increase ambivalence toward the current partner, above and beyond how much people actually value their partner, and that this has short- and long-term negative consequences for personal and relational well-being. Furthermore, while most people could identify an attractive alternative in their life, desire for the alternative-rather than just their presence-seems to play a stronger role in increasing ambivalence. This work highlights the emotional processes through which attractive alternatives pose a threat to romantic relationships and the role that ambivalence plays in daily life and over time. (PsycInfo Database Record (c) 2022 APA, all rights reserved).


Assuntos
Afeto , Emoções , Gerenciamento de Dados , Humanos , Relações Interpessoais
15.
J Pers Soc Psychol ; 123(4): 788-810, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34968138

RESUMO

Romantic partners regularly sacrifice their own self-interest when partners' needs and preferences diverge. The present work examines the role of perceived partner responsiveness (PPR)-impressions that one's partner is understanding, caring, and validating-in positively shaping people's appraisals of their relational sacrifices. In Study 1, a preregistered experiment of romantically involved individuals (N = 548), we manipulated PPR (high, low, or control) in a hypothetical sacrifice scenario. In Study 2, we tracked romantic couples' (N = 126) in-lab conversations about a sacrifice (Study 2a), and their sacrifices in daily life (Study 2b). In Study 3, romantic couples (N = 111) engaged in lab conversations about a sacrifice that entailed making a change that one partner desired from the other, and reported on their progress 2 weeks later. In Study 4, we surveyed romantically involved individuals (N = 230) who recently made a life-changing sacrifice by relocating to a new city or country to support their partner's career. Across studies, results showed that higher PPR fostered more positive sacrifice appraisals (i.e., lower costs and viewing the act as less of a sacrifice, greater satisfaction, greater personal and relational benefits, lower regret) and greater sacrifice behavior (Study 3)-in part due to greater closeness with and lower negative affect toward the partner. Additionally, Study 4 suggested that PPR partly originated from the partner's efforts to fulfill fundamental psychological needs (i.e., autonomy, competence, relatedness). Thus, PPR can play a critical role in lightening the load of daily and even life-changing sacrifices. (PsycInfo Database Record (c) 2022 APA, all rights reserved).


Assuntos
Emoções , Relações Interpessoais , Comunicação , Humanos , Satisfação Pessoal , Parceiros Sexuais/psicologia , Inquéritos e Questionários
16.
J Neurol Sci ; 432: 120061, 2022 01 15.
Artigo em Inglês | MEDLINE | ID: mdl-34894422

RESUMO

The exact incidence of neurological and cognitive sequelae of COVID-19 in the long term is yet unknown. The aim of this research is to investigate the type of neurological and cognitive impairment in COVID-19 cases of different severity. Two hundred fifteen patients, who had developed COVID-19, were examined 4 months after the diagnosis by means of neurological exam and extensive cognitive evaluation, investigating general cognition, memory, verbal fluency, visuospatial abilities and executive functions. Fifty-two of them were treated in intensive care unit (ICU patients), whereas 163 were not hospitalized (non-ICU patients). Neurological deficits were found in 2/163 (1.2%) of non-ICU and in 7/52 (13.5%) of the ICU cases, all involving the peripheral nervous system. ICU patients performed significantly worse in all the neuropsychological tests and showed a worse age- and education-corrected cognitive impairment: Cognitive Impairment Index (CII) was higher in ICU than in non-ICU patients (median ICU 3 vs 2, p = .001). CII significantly correlated with age in both groups, was unrelated to length of follow- up, diabetes and hypertension and - only for ICU patients- to PaO2/FiO2 at ICU admission. Obtained results support the greater susceptibility of COVID-19 patients, treated in ICU, to develop neurological deficits and cognitive impairment at a four-month follow up, as compared to cases with mild/moderate symptoms.


Assuntos
COVID-19 , RNA Viral , Cognição , Humanos , Unidades de Terapia Intensiva , SARS-CoV-2
17.
Int J Neonatal Screen ; 8(3)2022 Aug 09.
Artigo em Inglês | MEDLINE | ID: mdl-35997437

RESUMO

Newborn screening (NBS) for inborn errors of metabolism is one of the most advanced tools for secondary prevention in medicine, as it allows early diagnosis and prompt treatment initiation. The expanded newborn screening was introduced in Italy between 2016 and 2017 (Law 167/2016; DM 13 October 2016; DPCM 12-1-2017). A total of 1,586,578 infants born in Italy were screened between January 2017 and December 2020. For this survey, we collected data from 15 Italian screening laboratories, focusing on the metabolic disorders identified by tandem mass spectrometry (MS/MS) based analysis between January 2019 and December 2020. Aminoacidemias were the most common inborn errors in Italy, and an equal percentage was observed in detecting organic acidemias and mitochondrial fatty acids beta-oxidation defects. Second-tier tests are widely used in most laboratories to reduce false positives. For example, second-tier tests for methylmalonic acid and homocysteine considerably improved the screening of CblC without increasing unnecessary recalls. Finally, the newborn screening allowed us to identify conditions that are mainly secondary to a maternal deficiency. We describe the goals reached since the introduction of the screening in Italy by exchanging knowledge and experiences among the laboratories.

18.
Prenat Diagn ; 31(12): 1141-6, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22034048

RESUMO

OBJECTIVE: To determine the performance of screening for late pre-eclampsia (PE) by maternal characteristics, uterine artery Doppler and a set of biochemical markers at 11 + 0 to 13 + 6 weeks' gestation. METHODS: Prospectively enrolled women at 11 + 0 to 13 + 6 weeks. Maternal characteristics, highest UtA pulsatility index and serum placental biomarkers including pregnancy-associated plasma protein-A, placental growth factor, soluble fms-like tyrosine kinase 1, P-selectin and neutrophil gelatinase-associated lipocalin were recorded. RESULTS: The rate of PE was 2.5% (13/528). Four (0.8%) had severe PE. A combined screening model that included placental growth factor, soluble fms-like tyrosine kinase 1 and neutrophil gelatinase-associated lipocalin could detect 77% of PE at a 10% false-positive rate. Mean risk for mild PE was 8.8% ± 6.4, mean risk for severe PE was 38.6% ± 4.3. Mean risk for controls was 2% ± 4.1. CONCLUSION: This combination of maternal biochemical variables in the first trimester can detect a consistent number of late PE. Further studies on a new and independent series of data could confirm the presented results.


Assuntos
Biomarcadores/sangue , Pré-Eclâmpsia/diagnóstico por imagem , Proteínas de Fase Aguda , Adulto , Feminino , Previsões , Humanos , Lipocalina-2 , Lipocalinas/sangue , Programas de Rastreamento , Proteínas de Membrana/sangue , Selectina-P/sangue , Pré-Eclâmpsia/sangue , Valor Preditivo dos Testes , Gravidez , Primeiro Trimestre da Gravidez , Terceiro Trimestre da Gravidez , Proteína Plasmática A Associada à Gravidez/metabolismo , Estudos Prospectivos , Proteínas Proto-Oncogênicas/sangue , Ultrassonografia Doppler de Pulso , Artéria Uterina/diagnóstico por imagem , Receptor 1 de Fatores de Crescimento do Endotélio Vascular/sangue
19.
J Pers Soc Psychol ; 120(3): 626-650, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-32584097

RESUMO

Philosophers and scientists have long debated the nature of human social interactions and the prevalence of mutual dependence, conflict of interests, and power asymmetry in social situations. Yet, there is surprisingly little empirical work documenting the patterns of interdependence that people experience in daily life. We use experience sampling to study how people think about 3 dimensions of interdependence in daily life and how these dimensions relate to cooperation. In Study 1, 139 romantic couples (n = 278) reported on situations experienced with their partner (k = 6,766); in Study 2, individuals (n = 284) reported on situations experienced with any other person (k = 7,248), over the course of 1 week. Across both samples, we found that most social interactions were perceived as containing moderate mutual dependence, equal power, and corresponding interests. When couples reported on the same situation (Study 1), they largely agreed on their experienced interdependence and cooperation, suggesting that their reports reflect an underlying shared reality. In daily interactions across both samples, higher mutual dependence and lower conflict of interests were associated with more cooperation, whereas relative power was not directly related to cooperation. These associations replicated in laboratory experiments (Study 2). In daily life, high mutual dependence and high relative power exacerbated the negative relation between conflict of interests and cooperation. Finally, prevalent patterns of interdependence and the experience of specific interdependent situations affected multiple relationship outcomes. Our findings stress the importance of studying a diverse array of interdependent situations-and especially situations with corresponding interests-to better understand cooperation in daily life. (PsycInfo Database Record (c) 2021 APA, all rights reserved).


Assuntos
Atividades Cotidianas/psicologia , Conflito de Interesses , Comportamento Cooperativo , Dependência Psicológica , Relações Interpessoais , Poder Psicológico , Interação Social , Adulto , Idoso , Avaliação Momentânea Ecológica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Países Baixos , Adulto Jovem
20.
J Pers Soc Psychol ; 120(2): 335-369, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-32718166

RESUMO

Do people realize the evaluative feelings that are spontaneously activated by their partner? If so, do they use those evaluations when judging their romantic relationships? To answer these questions, we investigated the association between automatic partner attitudes and judgments of relationship satisfaction in 7 studies. Study 1 was a meta-analysis of 86 correlations that revealed a very weak association between implicitly and explicitly assessed relationship evaluations, and Studies 2a-2c revealed that people failed to accurately report their automatic partner attitudes even when specifically asked to do so. Consistent with the idea that such inaccuracy emerged in part because motivational factors led people to override their automatic attitudes, Studies 3 and 4 demonstrated that automatic partner attitudes better aligned with relationship judgments when people were incentivized with money (Study 3) and had dissolved their relationship (Study 4). Nevertheless, consistent with the idea that overriding automatic attitudes requires the opportunity to deliberate, Studies 4 and 5 demonstrated that automatic partner attitudes better aligned with relationship judgments when people experienced more stress at the daily level (Study 4) and yearly for two years (Study 5). In Study 5, the interaction between stress and automatic attitudes emerged controlling indicators of negativity and was further moderated by relationship enhancing motivations among wives. These studies (a) help explain why automatic partner attitudes predict self-reported relationship satisfaction over time and (b) provide support for theories of social cognition suggesting that people have access to implicitly assessed attitudes that is obscured by motivations and opportunities to deliberate. (PsycInfo Database Record (c) 2021 APA, all rights reserved).


Assuntos
Relações Interpessoais , Motivação , Satisfação Pessoal , Cônjuges/psicologia , Estresse Psicológico/psicologia , Adulto , Atitude , Emoções , Feminino , Humanos , Julgamento , Masculino , Pessoa de Meia-Idade , Autorrelato
SELEÇÃO DE REFERÊNCIAS
Detalhe da pesquisa