Detalhe da pesquisa
1.
Evaluation of the drug-drug interaction potential of treosulfan using a physiologically-based pharmacokinetic modelling approach.
Br J Clin Pharmacol
; 88(4): 1722-1734, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34519068
2.
Assessing consistency in clinical trials with two subgroups and binary endpoints: A new test within the logistic regression model.
Stat Med
; 39(30): 4551-4573, 2020 12 30.
Artigo
Inglês
| MEDLINE | ID: mdl-33105519
3.
The potential of the estimands framework for clinical pharmacology trials: Some discussion points.
Br J Clin Pharmacol
; 86(7): 1240-1247, 2020 07.
Artigo
Inglês
| MEDLINE | ID: mdl-32030776
4.
Statistical reporting of clinical pharmacology research.
Br J Clin Pharmacol
; 83(6): 1159-1162, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28321897
5.
A Phase I study to determine the pharmacokinetic profile, safety and tolerability of sildenafil (Revatio® ) in cardiac surgery: the REVAKI-1 study.
Br J Clin Pharmacol
; 83(4): 709-720, 2017 04.
Artigo
Inglês
| MEDLINE | ID: mdl-27779776
6.
Infarct size following complete revascularization in patients presenting with STEMI: a comparison of immediate and staged in-hospital non-infarct related artery PCI subgroups in the CvLPRIT study.
J Cardiovasc Magn Reson
; 18(1): 85, 2016 Nov 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27842548
7.
Linagliptin fixed-dose combination with metformin is bioequivalent to co-administration of linagliptin and metformin as individual tablets.
Int J Clin Pharmacol Ther
; 52(7): 537-48, 2014 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-24755123
8.
Effect of food and tablet-dissolution characteristics on the bioavailability of linagliptin fixed-dose combination with metformin: evidence from two randomized trials.
Int J Clin Pharmacol Ther
; 52(7): 549-63, 2014 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-24755124
9.
Group-by-Treatment Interaction Effects in Comparative Bioavailability Studies.
AAPS J
; 26(3): 50, 2024 Apr 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38632178
10.
Rationale, design, and organization of a randomized, controlled Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS) in patients with type 2 diabetes and established cardiovascular disease.
Am Heart J
; 166(6): 983-989.e7, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24268212
11.
The sodium glucose cotransporter 2 inhibitor empagliflozin does not prolong QT interval in a thorough QT (TQT) study.
Cardiovasc Diabetol
; 12: 70, 2013 Apr 24.
Artigo
Inglês
| MEDLINE | ID: mdl-23617452
12.
How publication guidelines for clinical pharmacology trials may help to accelerate knowledge transfer.
Br J Clin Pharmacol
; 84(4): 611-614, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29427380
13.
Pharmacokinetics of linagliptin in subjects with hepatic impairment.
Br J Clin Pharmacol
; 74(1): 75-85, 2012 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-22242621
14.
Pharmacokinetics of single and multiple oral doses of 5 mg linagliptin in healthy Chinese volunteers.
Int J Clin Pharmacol Ther
; 50(12): 889-95, 2012 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-23073142
15.
Delayed effects in the exposure-response analysis of clinical QTc trials.
J Biopharm Stat
; 22(2): 387-400, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22251181
16.
The DPP-4 inhibitor linagliptin does not prolong the QT interval at therapeutic and supratherapeutic doses.
Br J Clin Pharmacol
; 72(1): 39-50, 2011 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-21306414
17.
Mixed models for data from thorough QT studies: part 1. assessment of marginal QT prolongation.
Pharm Stat
; 10(3): 265-76, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-21574242
18.
Statistical models for heart rate correction of the QT interval.
Stat Med
; 29(7-8): 786-96, 2010 Mar 30.
Artigo
Inglês
| MEDLINE | ID: mdl-20213712
19.
Statistical characterization of QT prolongation.
J Biopharm Stat
; 20(3): 543-62, 2010 May.
Artigo
Inglês
| MEDLINE | ID: mdl-20358435
20.
Residuals and outliers in replicate design crossover studies.
J Biopharm Stat
; 20(4): 835-49, 2010 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-20496209