Detalhe da pesquisa
1.
Quantification of clesrovimab, an investigational, half-life extended, anti-respiratory syncytial virus protein F human monoclonal antibody in the nasal epithelial lining fluid of healthy adults.
Biomed Pharmacother
; 169: 115851, 2023 Dec 31.
Artigo
Inglês
| MEDLINE | ID: mdl-37976891
2.
An Investigation of Instability in Dried Blood Spot Samples for Pharmacokinetic Sampling in Phase 3 Trials of Verubecestat.
AAPS J
; 24(3): 52, 2022 04 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35384529
3.
Neutralization Activity of Anti-drug Antibodies Against a Biotherapeutic Can Be Predicted from a Comprehensive Pharmacokinetics, Pharmacodynamics, and Anti-drug Antibody Data Analysis.
AAPS J
; 24(6): 102, 2022 09 27.
Artigo
Inglês
| MEDLINE | ID: mdl-36167856
4.
A Phase 1 Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Safety, Tolerability, and Pharmacokinetics of a Respiratory Syncytial Virus Neutralizing Monoclonal Antibody MK-1654 in Healthy Adults.
Clin Pharmacol Drug Dev
; 10(5): 556-566, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33125189
5.
Forward and reverse translational approaches to predict efficacy of neutralizing respiratory syncytial virus (RSV) antibody prophylaxis.
EBioMedicine
; 73: 103651, 2021 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-34775220
6.
Clinical application of volumetric absorptive microsampling to the gefapixant development program.
Bioanalysis
; 12(13): 893-904, 2020 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-32648772
7.
Assessment of the CYP3A-mediated drug interaction potential of anacetrapib, a potent cholesteryl ester transfer protein (CETP) inhibitor, in healthy volunteers.
J Clin Pharmacol
; 49(1): 80-7, 2009 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-19004846
8.
Determination of doravirine in human plasma using liquid-liquid extraction and HPLC-MS/MS.
Bioanalysis
; 11(16): 1495-1508, 2019 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-31502859
9.
Use of minipig skin biopsy model as an innovative tool to design topical formulation to achieve desired pharmacokinetics in humans.
J Pharm Sci
; 104(5): 1701-8, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25691117
10.
Effect of sitagliptin on the pharmacokinetics of simvastatin.
J Clin Pharmacol
; 49(4): 483-8, 2009 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19204138
11.
Sensitive method for the quantitative determination of gemfibrozil in dog plasma by liquid-liquid cartridge extraction and liquid chromatography-tandem mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci
; 791(1-2): 161-70, 2003 Jul 05.
Artigo
Inglês
| MEDLINE | ID: mdl-12798176
12.
Mechanistic studies on metabolic interactions between gemfibrozil and statins.
J Pharmacol Exp Ther
; 301(3): 1042-51, 2002 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-12023536