1.
Bioorg Med Chem
; 3(12): 1693-8, 1995 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-8770394
RESUMO
The chiral synthesis of the potent and selective alpha-2A antagonist, BRL 48962, is described. Evaluation of BRL 48962 at cloned human alpha-adrenoceptors indicates that this antagonist has a selectivity in the order of 30-fold for the alpha-2A subtype.