RESUMO
Indirect laryngoscopy is one of the procedural methods used for achieving a histopathologic diagnosis of cancer of the larynx. A chronologic historical summary of the development of mirror laryngoscopy is presented. The details of the procedure employed for obtaining a biopsy with the aid of topical anesthesia is discussed.
Assuntos
Anestesia Intravenosa , Anestesia Local , Cocaína , História do Século XIX , História do Século XX , Humanos , Neoplasias Laríngeas/história , Neoplasias Laríngeas/cirurgia , Laringoscopia/história , Lidocaína , Medicação Pré-AnestésicaRESUMO
The usefulness of radionuclear scanning in the treatment of 18 patients with necrotizing progressive "malignant" external otitis is discussed. A Tc 99-m bone scan, a valuable test since results are positive in early cases of osteomyelitis of the temporal bone and base of skull, showed increased uptake in all 18 patients. In 6 patients, Ga-67 citrate scans were obtained at the start of therapy and at 5-6 week intervals thereafter. The serial gallium scans were useful in evaluating the effectiveness of therapy since the uptake decrease with control of infection.
Assuntos
Osteomielite/diagnóstico por imagem , Otite Externa/diagnóstico por imagem , Infecções por Pseudomonas/diagnóstico por imagem , Idoso , Complicações do Diabetes , Difosfonatos , Feminino , Radioisótopos de Gálio , Humanos , Masculino , Pessoa de Meia-Idade , Necrose , Osteomielite/tratamento farmacológico , Osteomielite/etiologia , Otite Externa/complicações , Otite Externa/tratamento farmacológico , Infecções por Pseudomonas/tratamento farmacológico , Cintilografia , Crânio/diagnóstico por imagem , Tecnécio , Medronato de Tecnécio Tc 99m , Osso Temporal/diagnóstico por imagemAssuntos
Carcinoma de Células Escamosas/radioterapia , Neoplasias Laríngeas/radioterapia , Neoplasias Faríngeas/radioterapia , Dosagem Radioterapêutica , Adulto , Idoso , Carcinoma de Células Escamosas/cirurgia , Feminino , Humanos , Neoplasias Laríngeas/cirurgia , Masculino , Pessoa de Meia-Idade , Recidiva Local de Neoplasia , Neoplasias Faríngeas/cirurgia , Complicações Pós-Operatórias , Cuidados Pré-OperatóriosAssuntos
Carcinoma/terapia , Neoplasias Laríngeas/terapia , Neoplasias Faríngeas/terapia , Carcinoma/patologia , Carcinoma/radioterapia , Carcinoma/cirurgia , Isótopos do Cobalto , Humanos , Neoplasias Laríngeas/patologia , Neoplasias Laríngeas/radioterapia , Neoplasias Laríngeas/cirurgia , Laringectomia , Laringe/patologia , Linfonodos/patologia , Esvaziamento Cervical , Metástase Neoplásica , Recidiva Local de Neoplasia , Neoplasias Faríngeas/patologia , Neoplasias Faríngeas/radioterapia , Neoplasias Faríngeas/cirurgia , Teleterapia por Radioisótopo , Dosagem RadioterapêuticaRESUMO
A carefully planned clinical program of combined pre-operative radiation and surgery has been conducted by the Department of Otolaryngology at The Mount Sinai Hospital for 14 years in an effort to improve the survival rate for advanced cancer of the larynx and laryngopharynx. An extensive histopathological study of resected larynges and radical neck specimens was undertaken in 1961 in order to determine the effects of pre-operative radiation. A very careful statistical analysis has been made of the survival experience of this series of cases. The three and five year survival rates have been computed by the actuarial method. The histopathological study entailed a serial section study of 26 larynges and 21 radical neck dissection specimens. These studies have been most informative as to the nature of the radiobiologic process involved in the destruction of laryngeal cancer. In addition, the study has been revealing as to the ability of radiation to sterilize cancer in the neck specimens. The clinical correlate of this histologic finding has been the observation of reduced cervical recurrences in patients treated with combined therapy. In conclusion, our statistics seem to indicate that our combined therapy method has improved the survival rates of patients with advanced cancer of the larynx and laryngopharynx.