Detalhe da pesquisa
1.
A rare germline CDKN2A variant (47T>G; p16-L16R) predisposes carriers to pancreatic cancer by reducing cell cycle inhibition.
J Biol Chem
; 296: 100634, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33823155
2.
The extracellular sulfatase SULF2 promotes liver tumorigenesis by stimulating assembly of a promoter-looping GLI1-STAT3 transcriptional complex.
J Biol Chem
; 295(9): 2698-2712, 2020 02 28.
Artigo
Inglês
| MEDLINE | ID: mdl-31988246
3.
GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression.
Biochem J
; 477(17): 3131-3145, 2020 09 18.
Artigo
Inglês
| MEDLINE | ID: mdl-32766732
4.
Induction of Lysosome-associated Protein Transmembrane 4 Beta via Sulfatase 2 Enhances Autophagic Flux in Liver Cancer Cells.
Hepatol Commun
; 3(11): 1520-1543, 2019 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-31701075
5.
Molecular Modeling and Functional Analysis of Exome Sequencing-Derived Variants of Unknown Significance Identify a Novel, Constitutively Active FGFR2 Mutant in Cholangiocarcinoma.
JCO Precis Oncol
; 20172017.
Artigo
Inglês
| MEDLINE | ID: mdl-30761385