Detalhe da pesquisa
1.
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer.
Nat Immunol
; 23(10): 1495-1506, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36151395
2.
A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering.
Cell
; 179(5): 1222-1238.e17, 2019 11 14.
Artigo
Inglês
| MEDLINE | ID: mdl-31730859
3.
Defining a Cancer Dependency Map.
Cell
; 170(3): 564-576.e16, 2017 Jul 27.
Artigo
Inglês
| MEDLINE | ID: mdl-28753430
4.
Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma.
Mol Cell
; 84(2): 261-276.e18, 2024 Jan 18.
Artigo
Inglês
| MEDLINE | ID: mdl-38176414
5.
NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition.
Mol Cell
; 82(13): 2472-2489.e8, 2022 07 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35537449
6.
KRAS and YAP1 converge to regulate EMT and tumor survival.
Cell
; 158(1): 171-84, 2014 Jul 03.
Artigo
Inglês
| MEDLINE | ID: mdl-24954536
7.
Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex.
Nature
; 609(7926): 408-415, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35831509
8.
Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations.
Nat Methods
; 2024 Apr 09.
Artigo
Inglês
| MEDLINE | ID: mdl-38594452
9.
The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity.
Nat Immunol
; 16(5): 495-504, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25848864
10.
Cancer vulnerabilities unveiled by genomic loss.
Cell
; 150(4): 842-54, 2012 Aug 17.
Artigo
Inglês
| MEDLINE | ID: mdl-22901813
11.
ß-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.
Cell
; 151(7): 1457-73, 2012 Dec 21.
Artigo
Inglês
| MEDLINE | ID: mdl-23245941
12.
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.
Cell
; 150(3): 575-89, 2012 Aug 03.
Artigo
Inglês
| MEDLINE | ID: mdl-22863010
13.
Systematic discovery of TLR signaling components delineates viral-sensing circuits.
Cell
; 147(4): 853-67, 2011 Nov 11.
Artigo
Inglês
| MEDLINE | ID: mdl-22078882
14.
Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5.
Cell
; 143(1): 122-33, 2010 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20887897
15.
WRN helicase is a synthetic lethal target in microsatellite unstable cancers.
Nature
; 568(7753): 551-556, 2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30971823
16.
Acquired Resistance to KRASG12C Inhibition in Cancer.
N Engl J Med
; 384(25): 2382-2393, 2021 06 24.
Artigo
Inglês
| MEDLINE | ID: mdl-34161704
17.
Systematic identification of biomarker-driven drug combinations to overcome resistance.
Nat Chem Biol
; 18(6): 615-624, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35332332
18.
A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection.
Cell
; 139(7): 1255-67, 2009 Dec 24.
Artigo
Inglês
| MEDLINE | ID: mdl-20064372
19.
Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells.
Cell
; 137(5): 821-34, 2009 May 29.
Artigo
Inglês
| MEDLINE | ID: mdl-19490892
20.
DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells.
Nature
; 563(7732): 522-526, 2018 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30464262