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1.
Artigo em Inglês | MEDLINE | ID: mdl-38708438

RESUMO

Computed tomography (CT) is commonly used in the staging of hepatic masses and for liver lobectomy planning. Mass location is an important factor in determining the feasibility of resection, including surgical technique and the likelihood of surgical complications. The objectives of this retrospective descriptive cross-sectional, observer agreement, method comparison study were to assess the reliability of CT in correctly determining the hepatic division and lobar site of origin of feline primary nonhematopoietic hepatic masses, compared with surgically confirmed locations. Furthermore, it provides an overview of the types and locations of liver masses found in a cohort of cats. Pre- and postcontrast CT images of 21 cats were independently and simultaneously reviewed by two observers. Intra- and interobserver agreements and descriptive statistics on demographic and histological diagnoses were calculated. Based on surgical assessment, it was found that masses most frequently originated from the left hepatic division (13/24, 54%). The most frequent lobar origins were the left lateral (8/24, 33%), left medial (5/24, 21%), and right medial lobes (5/24, 21%). No masses were found originating from the right lateral lobe. CT correctly determined hepatic division and lobar origin in 76% of cases, with good-to-excellent intra- and interobserver agreement. The hepatic division had higher agreements overall for both observers. Most of the masses were benign (17/21, 81%), and the most prevalent histological diagnoses were biliary cystadenoma (11/21, 52%) and hepatocellular adenoma (6/21, 29%). Findings suggest that postcontrast CT is a reliable method for correctly determining hepatic mass division and lobar origin in cats.

2.
Vet Surg ; 52(3): 370-378, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36647241

RESUMO

OBJECTIVE: The objective of this study was to describe the clinical features, prognostic factors, and outcomes in dogs with surgically treated salivary gland carcinoma. STUDY DESIGN: Multi-institutional retrospective case series. ANIMALS: Seventy-two client-owned dogs from 16 institutions with surgically excised salivary gland carcinoma. METHODS: Medical records of dogs undergoing sialoadenectomy from January 1, 2000 to January 1, 2020 were reviewed for signalment, clinical signs, preoperative staging results, preoperative mass evaluation, complications, histopathologic diagnosis, local recurrence, metastatic disease, and survival times. Survival functions were estimated using the Kaplan-Meier estimator. Factors related to survival were individually tested using the log-rank test. RESULTS: The overall median survival time (MST) associated with salivary carcinoma was 1886 days. Local recurrence occurred in 29/69 (42%) dogs with an overall disease-free interval (DFI) of 191 days. Metastatic disease occurred in 22/69 (31.9%) dogs, with an overall DFI of 299 days. Lymph node metastasis was present at the time of surgery in 11/38 (28.9%) dogs in which lymphadenectomy was performed at the time of surgery; these dogs had a shorter DFI at 98 days (P = .03) and MST at 248 days (P < .001). CONCLUSION: The prognosis for dogs with salivary gland carcinoma treated surgically was more favorable than previously reported. Nodal metastasis was a negative prognostic factor for canine salivary gland carcinoma. CLINICAL SIGNIFICANCE: Surgical intervention should be considered for dogs with salivary carcinoma.


Assuntos
Carcinoma , Doenças do Cão , Oncologia Cirúrgica , Cães , Animais , Estudos Retrospectivos , Resultado do Tratamento , Sociedades Veterinárias , Prognóstico , Carcinoma/cirurgia , Carcinoma/veterinária , Doenças do Cão/diagnóstico
3.
Vet Surg ; 51(1): 109-116, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34669214

RESUMO

OBJECTIVE: To describe the clinical presentation, treatments, and long-term outcomes following cholecystectomy in cats. STUDY DESIGN: Clinical retrospective study. ANIMALS: Twenty-three client-owned cats. METHODS: Medical records of all cats undergoing cholecystectomy between 2005 and 2021 at a single referral hospital were retrospectively reviewed. No cats were excluded. An owner questionnaire assessed long-term outcomes. RESULTS: Vomiting, jaundice, and abdominal pain were the most common clinical signs; median duration of signs was 4 days (range 1-21). Cholelithiasis was the major indication for cholecystectomy followed by cholecystitis. Intraoperative hypotension and postoperative anemia were commonly encountered. Nine cats required a postoperative blood product transfusion. Cardiopulmonary arrest and death occurred in five cats. Eighteen cats (78.3%) survived to discharge. Long-term follow up (>60 days) was available for 16 cats at a median of 1003 days (range 81-4995). Fifteen cats survived over 6 months with eight cats (44.4%) surviving over 3 years. The most common short-term and long-term postoperative complication was vomiting. Owners assessed postoperative outcome as excellent in all cats and quality of life as excellent or good. CONCLUSION: The most common indication for cholecystectomy was cholelithiasis. Perioperative complications were commonly encountered. Perioperative mortality rate was 21.7%. Long-term owner evaluation of clinical outcome was considered excellent. CLINICAL SIGNIFICANCE: Cats undergoing cholecystectomy for non-neoplastic causes can have a favorable prognosis for recovery and quality of life. Concurrent extrahepatic biliary duct obstruction is not a contraindication for cholecystectomy provided that patency of the common bile duct is restored.


Assuntos
Doenças do Gato , Colecistectomia Laparoscópica , Colestase Extra-Hepática , Animais , Doenças do Gato/cirurgia , Gatos , Colecistectomia/veterinária , Colecistectomia Laparoscópica/veterinária , Colestase Extra-Hepática/cirurgia , Colestase Extra-Hepática/veterinária , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/veterinária , Qualidade de Vida , Estudos Retrospectivos , Resultado do Tratamento
4.
Vet Surg ; 51(3): 397-408, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-34997760

RESUMO

OBJECTIVE: To report complications and long-term outcomes after submucosal resections of benign and malignant epithelial rectal masses. STUDY DESIGN: Retrospective multicentric study. SAMPLE POPULATION: Medical records of 93 dogs at 7 referral hospitals. METHODS: Records were reviewed for surgical time, diagnosis, margins, complications, and recurrences. Survival of dogs was evaluated based on tumor types, categorized as benign, carcinoma in situ, and carcinoma. The Kaplan-Meier survival curve and Cox proportional hazards analysis were used to determine the association of a range of variables with recurrence and survival time. RESULTS: Duration of follow up was 708 days (range, 25-4383). Twenty-seven dogs (29%) developed complications. Recurrence was identified in 20/93 (21%), with 12/20 recurrent masses treated with repeat submucosal resection. Median survival was not reached in any group. The 1-,2-, 5-year survival rates for carcinomas were 95%, 89%, and 73% respectively. However, overall survival was longer for benign tumors than carcinomas (P = .001). Recurrence was more likely when complications (P = .032) or incomplete margins (P = .023) were present. Recurrence was associated with an increased risk of death (P = .046). CONCLUSION: Submucosal resection of both benign and malignant rectal masses was associated with a low rate of severe complications and prolonged survival in the 93 dogs described here. CLINICAL SIGNIFICANCE: Submucosal resection is a suitable technique for resection of selected rectal masses.


Assuntos
Carcinoma , Doenças do Cão , Recidiva Local de Neoplasia , Neoplasias Retais , Animais , Carcinoma/cirurgia , Carcinoma/veterinária , Doenças do Cão/cirurgia , Cães , Recidiva Local de Neoplasia/cirurgia , Recidiva Local de Neoplasia/veterinária , Neoplasias Retais/cirurgia , Neoplasias Retais/veterinária , Reto/patologia , Estudos Retrospectivos , Resultado do Tratamento
5.
Vet Surg ; 51(6): 990-1001, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35765719

RESUMO

OBJECTIVE: To determine and compare median sternotomy (MS) closure-related complication rates using orthopedic wire or suture in dogs. STUDY DESIGN: Multi-institutional, retrospective observational study with treatment effect analysis. ANIMALS: 331 client-owned dogs, of which 68 were excluded. METHODS: Medical records of dogs with MS were examined across nine referral centers (2004-2020). Signalment, weight, clinical presentation, surgical details, complications, and outcomes were recorded. Follow-up was performed using patient records and email/telephone contact. Descriptive statistics, treatment effect analysis and logistic regression were performed. RESULTS: Median sternotomy closure was performed with wire in 115 dogs and suture in 148. Thirty-seven dogs experienced closure-related complications (14.1%), 20 in the wire group and 17 in the suture group. Twenty-three were listed as mild, four as moderate and 10 as severe. Treatment effect analysis showed a mean of 2.3% reduction in closure-related complications associated with using suture versus wire (95% CI: -9.1% to +4.5%). In multivariable logistic regression, the only factor associated with increased risk of closure-related complications was dog size (p = .01). This effect was not modified by the type of closure used (interaction term: OR = 0.99 [95% CI: 0.96/1.01]). CONCLUSION: The incidence of closure-related complication after MS was low compared to previous reports. The likelihood of developing a closure-related complication was equivalent between sutures and wires, independent of dog size, despite a higher proportion of complications seen in larger dogs (≥20 kg). CLINICAL SIGNIFICANCE: Use of either orthopedic wire or suture appear to be an appropriate closure method for sternotomy in dogs of any size.


Assuntos
Esternotomia , Técnicas de Sutura , Animais , Fios Ortopédicos/veterinária , Cães , Estudos Retrospectivos , Esternotomia/efeitos adversos , Esternotomia/veterinária , Técnicas de Sutura/efeitos adversos , Técnicas de Sutura/veterinária , Suturas/efeitos adversos , Suturas/veterinária , Técnicas de Fechamento de Ferimentos/efeitos adversos , Técnicas de Fechamento de Ferimentos/veterinária
6.
Vet Surg ; 50(2): 402-409, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33331095

RESUMO

OBJECTIVE: To describe and report the outcomes after closure of median sternotomies with crimped monofilament nylon leader (MNL) in dogs. STUDY DESIGN: Retrospective observational study. ANIMALS: Dogs (n = 10) that underwent intrathoracic surgery through a median sternotomy approach. METHODS: The median sternotomy was closed in a peristernal figure eight pattern with crimped MNL. Medical records were reviewed for clinical and histopathological findings and complications. Owners or veterinarians were contacted to collect long-term follow-up information. RESULTS: The technique was simple, with no intraoperative complications. Postoperative infection was documented in one dog, requiring removal of a single MNL and associated crimp clamp. Delayed healing of the surgical incision in one dog was managed conservatively. No other complications were documented throughout long-term follow-up at a median of 488 days (range, 199-608). CONCLUSION: Median sternotomies were successfully closed with crimped MNL and were associated with a low complication rate. CLINICAL SIGNIFICANCE: Crimped MNL represents an alternative method to close median sternotomies in dogs.


Assuntos
Cães/cirurgia , Nylons , Complicações Pós-Operatórias/veterinária , Esternotomia/veterinária , Animais , Feminino , Masculino , Complicações Pós-Operatórias/etiologia , Estudos Retrospectivos , Esternotomia/instrumentação , Procedimentos Cirúrgicos Torácicos/veterinária , Cicatrização
7.
Vet Surg ; 50(5): 1023-1031, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-33480061

RESUMO

OBJECTIVE: To describe the technique and outcomes after placement of sutures around the sacrotuberous ligament during perineal hernia (PH) repair in dogs. STUDY DESIGN: Retrospective single-center study. ANIMALS: Dogs (n = 47) with PH. METHODS: Medical records of dogs treated for PH between 2002 and 2020 were reviewed. Dogs were included when sutures had been placed around the sacrotuberous ligament. Short-term outcomes and intraoperative and postoperative complications were recorded. Long-term outcome was assessed with a questionnaire completed by owners. RESULTS: Twenty-eight of 47 dogs were medium or large breeds. The primary clinical sign was tenesmus in 43 dogs and dysuria-stranguria in four dogs. Bilateral hernias were detected in 17 dogs. No intraoperative complications occurred. Median surgical time was 50 minutes for unilateral PH and 120 minutes for bilateral PH. Minor postoperative complications consisting of surgical wound swelling (9), wound dehiscence (4), and temporary tenesmus (2) occurred in 10 dogs. No major complications or recurrence were reported. The only factors associated with an increased risk of complications included increasing age (P = .019) and surgical treatment of a recurrent PH (P = .043). Owners consistently reported good long-term outcomes. CONCLUSION: The PH repair described in this study resulted in good long-term outcomes without major complications. CLINICAL SIGNIFICANCE: Placement of sutures around the sacrotuberous ligament represents an alternative during PH, but anatomical knowledge of the sciatic nerve and caudal gluteal vessels is required.


Assuntos
Doenças do Cão/cirurgia , Hérnia/veterinária , Herniorrafia/veterinária , Ligamentos Articulares/cirurgia , Períneo , Animais , Cães , Herniorrafia/métodos , Complicações Intraoperatórias/veterinária , Masculino , Complicações Pós-Operatórias/veterinária , Reto/lesões , Estudos Retrospectivos , Nervo Isquiático/lesões , Técnicas de Sutura/veterinária
8.
Vet Surg ; 50(3): 579-587, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33638933

RESUMO

OBJECTIVE: To compare complications of dogs treated with mandibular and sublingual sialoadenectomy for sialocele using a lateral (LAT) or ventral paramedian (VPM) approach. STUDY DESIGN: Retrospective multicenter study. ANIMALS: Dogs (140) with mandibular and sublingual sialocele. METHODS: Medical records of dogs that underwent mandibular and sublingual sialoadenectomy through a LAT or VPM approach from 2004 to 2020 were reviewed. Clinical and histopathological findings were analyzed to compare the groups. RESULTS: Seventy dogs were included in each group. The most represented breed was crossbreed (26%), and males (99/140 [71%], intact/neutered) were overrepresented. Dogs in the VPM approach group were more likely to undergo digastricus tunnelization and placement of a drain or a bandage. Dogs in the LAT approach group were heavier and more likely to undergo excision of an inflammatory pseudocapsule. No difference was detected in complication rates between groups (LAT [20%], VPM [31%], P = .116). Recurrences were more likely after LAT approach (5/70 vs 0/70, respectively; P = .029), whereas wound-related complications were more likely after VPM approach (20/70 vs 9/70, respectively; P = .018). Prolonged duration of surgery was associated with an increased risk of recurrence, and none of the other variables affected the complication rate. CONCLUSION: Ventral paramedian approach for mandibular and sublingual sialoadenectomy was associated with a lower risk of recurrence but a higher risk of wound-related complications compared with LAT approach. CLINICAL SIGNIFICANCE: Ventral paramedian approach for mandibular and sublingual sialoadenectomy may be preferred to reduce recurrence in dogs with sialoceles, but wound-related complications are common.


Assuntos
Cistos/veterinária , Doenças do Cão/cirurgia , Mucocele/veterinária , Complicações Pós-Operatórias/veterinária , Doenças da Glândula Submandibular/veterinária , Animais , Cistos/cirurgia , Cães , Feminino , Masculino , Mucocele/cirurgia , Complicações Pós-Operatórias/epidemiologia , Estudos Retrospectivos , Doenças da Glândula Submandibular/patologia , Doenças da Glândula Submandibular/cirurgia
9.
J Am Anim Hosp Assoc ; 57(3): 133-138, 2021 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-33770172

RESUMO

An 11 yr old female neutered domestic shorthair presented for an 8 mo history of an asymptomatic abdominal mass. Computed tomography described an irregular, cystic structure closely associated with the duodenum, and focal ultrasonography confirmed the mass shared outer layers with the intestinal wall. Coeliotomy revealed the mass was originating from, and firmly adhered to, the antimesenteric border of the duodenum but was not communicating with the intestinal lumen. En bloc mass resection with omentalization was performed without small intestinal resection. Histopathology confirmed an enteric duplication cyst. The cat made a full recovery and remained asymptomatic postoperatively with no evidence of recurrence. A review of the literature confirms the duodenum to be the most common location of enteric duplication cysts in felines and that subtotal excision is curative in most cases. This differential should be considered in cases of cystic gastrointestinal structures in juvenile and adult felines, with or without associated clinical signs. In cases of luminal involvement or malignant transformation, intestinal resection and anastomosis is more appropriate. This report describes the presentation, investigations, and treatment of an asymptomatic duodenal duplication cyst in an adult feline and summarizes and compares current knowledge of the condition between veterinary and human literature.


Assuntos
Doenças do Gato/diagnóstico , Cistos/veterinária , Duodenopatias/veterinária , Animais , Doenças do Gato/diagnóstico por imagem , Doenças do Gato/cirurgia , Gatos , Cistos/diagnóstico , Diagnóstico Diferencial , Duodenopatias/diagnóstico , Feminino , Tomografia Computadorizada por Raios X/veterinária , Ultrassonografia/veterinária
10.
Vet Surg ; 49(4): 659-667, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-32170778

RESUMO

OBJECTIVE: To report outcomes of dogs treated for lung lobe torsion (LLT) and to determine prognostic factors for survival. STUDY DESIGN: Retrospective multicenter study from four veterinary teaching hospitals. ANIMALS: Dogs (n = 80) with LLT. METHODS: Medical records were reviewed for clinical and histopathological findings. Long-term outcome was assessed with an owner questionnaire. Lung lobe torsion was classified as idiopathic or secondary on the basis of the etiology. RESULTS: The most represented breeds were pugs (47.5%) and sighthounds (16.2%). The cause of the LLT was considered primary in 77%, secondary in 21%, and unknown in 2% of dogs. Postoperative complications were recorded in 14% of dogs. Overall, 95% of dogs survived to discharge, and median follow-up was 1095 days (range, 7-3809). Owners assessed outcomes and quality of life as excellent in 93% and 89% of dogs, respectively. Primary LLT was associated with a longer survival (median not reached in the study) compared with secondary LLT (921 days; range, 7-2073; P = .001). CONCLUSION: Overall long-term survival after lung lobectomy for LLT was excellent. Primary LLT was associated with longer survival compared with secondary LLT. Long-term owner evaluation of clinical outcome for dogs undergoing lung lobectomy for LLT was considered excellent. CLINICAL IMPACT: Dogs with primary LLT undergoing lung lobectomy have a longer survival time compared with dogs with secondary LLT and have an excellent postoperative outcome.


Assuntos
Doenças do Cão/cirurgia , Pneumopatias/veterinária , Complicações Pós-Operatórias/veterinária , Anormalidade Torcional/veterinária , Animais , Cães , Feminino , Longevidade , Pneumopatias/cirurgia , Masculino , Qualidade de Vida , Estudos Retrospectivos , Anormalidade Torcional/etiologia , Anormalidade Torcional/cirurgia , Resultado do Tratamento
11.
J Am Anim Hosp Assoc ; 56(3): 185, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32182111

RESUMO

Intravascular lymphoma (IVL) is a rare, high-grade, extranodal lymphoma characterized by selective proliferation of neoplastic lymphocytes within the lumen of small vessels. A 10 yr old female intact mixed-breed dog was presented with a 7 mo history of vomiting and anorexia. Physical examination revealed abdominal discomfort. Ultrasonography and endoscopy identified a submucosal gastric mass. Excision was performed by partial gastrectomy and histopathology and immunohistochemistry confirmed a T-cell IVL. The owner declined chemotherapy, and the dog was instead treated palliatively with prednisolone. Two months after surgery, vomiting recurred and abdominal ultrasonography revealed a large gastric ulcer with focal peritonitis. The dog was euthanized 4 mo after initial presentation and postmortem examination confirmed IVL recurrence in the stomach and an isolated nodule of neoplastic cells in the omentum. No involvement of other organs was found following histopathological examination. This is the first description of primary gastric intravascular lymphoma causing chronic vomiting in a dog.


Assuntos
Doenças do Cão/diagnóstico , Linfoma/veterinária , Estômago , Neoplasias Vasculares/veterinária , Animais , Diagnóstico Diferencial , Doenças do Cão/diagnóstico por imagem , Cães , Eutanásia Animal , Feminino , Gastrectomia/veterinária , Linfoma/diagnóstico , Ultrassonografia/veterinária , Neoplasias Vasculares/diagnóstico
12.
Vet Surg ; 43(8): 1009-13, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24617928

RESUMO

OBJECTIVE: To evaluate the efficacy of steam and ethylene oxide (EtO) sterilization of Vetrap™ bandages. STUDY DESIGN: Prospective experimental study. SAMPLE POPULATION: Vetrap™ bandages (n = 70; 35 as supplied by the manufacturer, 35 unwound and tightly rewound). METHODS: Vetrap™ bandage rolls (n = 60) marked with a 1 cm square were inoculated with 0.1 mL Geobacillus stearothermophilus spores, packaged in a pouch together with independent sterilization indicators and assigned into 3 sub-groups for sterilizer type: dynamic air removal, gravity displacement, and bench-top pre-vacuum and further sub-divided into 2 sterilization temperatures. Vetrap™ bandages rolls (n = 10) were inoculated with 0.1 mL Bacillus atrophaeus spores in the same manner and underwent EtO sterilization. After sterilization, the 1 cm marked square was aseptically resected to the level of the cardboard tube and enriched in a flask containing 10 mL tryptic soy broth for 24 hours at 60°C for G. stearothermophilus and 37°C for B. atrophaeus. Aliquots were subsequently plated on a Petri dish of tryptic soy agar and incubated at 60°C for G. stearothermophilus and 37°C for B. atrophaeus for 24 hours. Samples were scored positive if colonies of indicator organism were present on the nutrient agar after 24 hours. RESULTS: Three Vetrap™ bandages yielded post-sterilization growth of G. stearothermophilus: 2 from the dynamic air removal sterilizer at 134°C for 3.5 minutes, and 1 from the bench-top pre-vacuum sterilizer at 121°C for 15 minutes. After EtO sterilization, no positive samples were detected. CONCLUSIONS: Steam sterilization may be incomplete for Vetrap™ bandages whereas EtO showed complete destruction of resistant bacterial spores.


Assuntos
Vapor , Esterilização/métodos , Animais , Bacillus/efeitos dos fármacos , Bacillus/crescimento & desenvolvimento , Bandagens , Óxido de Etileno/farmacologia , Geobacillus stearothermophilus/efeitos dos fármacos , Geobacillus stearothermophilus/crescimento & desenvolvimento , Látex , Estudos Prospectivos , Esporos Bacterianos/efeitos dos fármacos , Esporos Bacterianos/crescimento & desenvolvimento
13.
J Am Vet Med Assoc ; : 1-10, 2024 Jun 19.
Artigo em Inglês | MEDLINE | ID: mdl-38901451

RESUMO

OBJECTIVE: To describe complications and outcomes in dogs undergoing epicardial pacemaker (EP) implantation, identify factors associated with survival, and investigate improvement in clinical signs and health-related quality of life (HRQoL) following surgery. ANIMALS: 52 client-owned dogs that underwent EP placement. METHODS: Medical records of 4 UK-based referral hospitals were searched and data reviewed retrospectively between July 2010 and December 2022. Factors contributing to outcomes after EP placement were assessed. RESULTS: The primary reasons for referral included collapsing/syncopal episodes (n = 36), exercise intolerance (15), and significant bradycardia (46). Third-degree atrioventricular block (39/52 [75%]) was the predominant indication for pacemaker placement, and common reasons for EP placement included previous transvenous pacemaker dislodgment/loss of capture (n = 12) and small body size (10). Intra- and postoperative complications were documented in 11% and 23% of dogs, respectively. Overall, 96% of dogs survived to discharge, and median follow-up time was 462 days (range, 31 to 3,139 days). Presence of coexistent myocardial or valvular disease at the time of EP implantation was associated with a reduced survival. Owners reported decreased clinical signs, increased activity levels, and improved HRQoL. CLINICAL RELEVANCE: Epicardial pacemaker implantation is a valuable option for dogs requiring artificial cardiac pacing. Complications were common but did not impact the overall outcome. Dogs with a coexisting cardiac pathology had a shorter life expectancy after EP placement, but their HRQoL appeared to be good, with an improvement in clinical signs and increased activity levels.

14.
J Vet Intern Med ; 37(4): 1488-1492, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37381579

RESUMO

Visceral hemangiosarcomas (HSA) are rare in cats and typically associated with aggressive biologic behavior and poor prognosis. A 4-year-old male neutered domestic shorthair cat was presented with a 3-month history of hematuria and stranguria; ultrasonography identified a large bladder mass. Complete excision was achieved by partial cystectomy. Histopathology and immunohistochemistry for von Willebrand factor confirmed HSA. The cat was treated using adjuvant cyclophosphamide, thalidomide, and meloxicam for 8 months. Abdominal ultrasonography repeated at 2 months and computed tomography repeated at 5 and 19 months after diagnosis showed no evidence of local recurrence or metastasis. The cat was alive at last follow-up (896 days). Although the cat described in this report experienced a more favorable prognosis compared to other visceral HSA locations, additional cases are needed to further understand the biological behavior of bladder HSAs and guide treatment decisions.


Assuntos
Doenças do Gato , Hemangiossarcoma , Neoplasias da Bexiga Urinária , Masculino , Gatos , Animais , Bexiga Urinária/cirurgia , Bexiga Urinária/patologia , Cistectomia/veterinária , Hemangiossarcoma/veterinária , Talidomida , Ciclofosfamida/uso terapêutico , Adjuvantes Imunológicos , Doenças do Gato/tratamento farmacológico , Doenças do Gato/cirurgia , Neoplasias da Bexiga Urinária/tratamento farmacológico , Neoplasias da Bexiga Urinária/cirurgia , Neoplasias da Bexiga Urinária/veterinária
15.
J Am Vet Med Assoc ; 261(11): 1646-1652, 2023 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-37582488

RESUMO

OBJECTIVE: To determine the prevalence of splenic malignancy in cats undergoing splenectomy and to investigate possible factors associated with post-operative outcome. ANIMALS: 62 client-owned cats that underwent splenectomy. METHODS: Medical records of 4 UK-based referral hospitals were searched and data reviewed retrospectively over 17 years. Factors associated with outcomes post-splenectomy were analyzed. RESULTS: 50 out of 62 cats (81%) were diagnosed with splenic neoplasia. Mast cell tumor ([MCT], 42%), hemangiosarcoma ([HSA], 40%), lymphoma and histiocytic sarcoma (6% each) were the most common tumor types. Fifteen cats (24%) presented with spontaneous hemoabdomen and were all diagnosed with splenic neoplasia. The diagnostic accuracy of cytology to detect splenic malignant lesions was 73% (100% for MCTs and 54% for mesenchymal tumors). Median survival time for cats with nonneoplastic splenic lesions was 715 days (IQR, 18 to 1,368) and 136 days for cats with splenic neoplasia (IQR, 35 to 348); median survival time was longer for cats with splenic MCT when compared to cats with HSA (348 vs 94 days; P < .001). Presence of metastatic disease and anemia (PCV < 24%) at diagnosis were associated with a poorer survival when considering all cats. Presence of anemia, a splenic mass on imaging or spontaneous hemoabdomen were associated with a diagnosis of HSA (P < .001). CLINICAL RELEVANCE: Benign splenic lesions were uncommon in this cohort of cats. Spontaneous hemoabdomen should prompt the clinician to suspect neoplasia in cats with splenic disease. Anemia and evidence of metastasis at diagnosis were poor prognostic factors regardless of the final diagnosis.


Assuntos
Anemia , Doenças do Gato , Doenças do Cão , Hemangiossarcoma , Neoplasias Esplênicas , Humanos , Gatos , Animais , Cães , Esplenectomia/efeitos adversos , Esplenectomia/veterinária , Estudos Retrospectivos , Prevalência , Neoplasias Esplênicas/epidemiologia , Neoplasias Esplênicas/cirurgia , Neoplasias Esplênicas/veterinária , Anemia/veterinária , Hemoperitônio/veterinária , Doenças do Cão/diagnóstico , Hemangiossarcoma/veterinária , Doenças do Gato/epidemiologia
16.
J Feline Med Surg ; 25(1): 1098612X221135124, 2023 01.
Artigo em Inglês | MEDLINE | ID: mdl-36706013

RESUMO

CASE SERIES SUMMARY: Twenty-nine cats from different institutions with confirmed or highly suspected primary hyperaldosteronism treated by unilateral adrenalectomy were retrospectively included in this study. The most frequent clinical signs were lethargy (n = 20; 69%) and neck ventroflexion (n = 17; 59%). Hypokalaemia was present in all cats, creatinine kinase was elevated in 15 and hyperaldosteronism was documented in 24. Hypertension was frequently encountered (n = 24; 89%). Preoperative treatment included potassium supplementation (n = 19; 66%), spironolactone (n = 16; 55%) and amlodipine (n = 11; 38%). There were 13 adrenal masses on the right side, 15 on the left and, in one cat, no side was reported. The median adrenal mass size was 2 × 1.5 cm (range 1-4.6 × 0.4-3.8); vascular invasion was present in five cats, involving the caudal vena cava in four cats and the renal vein in one. Median duration of surgery was 57 mins. One major intraoperative complication (3%) was reported and consisted of haemorrhage during the removal of a neoplastic thrombus from the caudal vena cava. In 4/29 cats (14%), minor postoperative complications occurred and were treated medically. One fatal complication (3%) was observed, likely due to disseminated intravascular coagulation. The median duration of hospitalisation was 4 days; 97% of cats survived to discharge. The potassium level normalised in 24 cats within 3 months of surgery; hypertension resolved in 21/23 cats. Follow-up was available for 25 cats with a median survival of 1082 days. Death in the long-term follow-up was mainly related to worsening of comorbidities. RELEVANCE AND NOVEL INFORMATION: Adrenalectomy appears to be a safe and effective treatment with a high rate of survival and a low rate of major complications. Long-term medical treatment was not required.


Assuntos
Neoplasias das Glândulas Suprarrenais , Doenças do Gato , Hiperaldosteronismo , Hipertensão , Gatos , Animais , Adrenalectomia/veterinária , Adrenalectomia/efeitos adversos , Estudos Retrospectivos , Hiperaldosteronismo/cirurgia , Hiperaldosteronismo/veterinária , Hiperaldosteronismo/complicações , Resultado do Tratamento , Hipertensão/veterinária , Potássio , Neoplasias das Glândulas Suprarrenais/complicações , Neoplasias das Glândulas Suprarrenais/cirurgia , Neoplasias das Glândulas Suprarrenais/veterinária , Doenças do Gato/cirurgia
17.
J Feline Med Surg ; 25(9): 1098612X231193534, 2023 09.
Artigo em Inglês | MEDLINE | ID: mdl-37713178

RESUMO

OBJECTIVES: The present study aimed to document the use of the wound infusion catheter (WIC) following a variety of surgical procedures in cats, investigating complications and risk factors associated with catheter placement or local anaesthetic (LA) administration. METHODS: A retrospective, multicentric study was performed. Medical databases of eight veterinary referral hospitals from 2010 to 2021 were searched to identify records of cats where WICs were used. Information regarding signalment, type of surgery, size and type of WIC placed, and LA protocol used, as well as postoperative complications, were retrieved. RESULTS: One hundred and sixty-six cases fulfilled the inclusion criteria. Feline injection site sarcoma resection was the most common surgery. Overall complications were identified in 22/166 cats (13.2%). Thirteen cats (7.8%) experienced wound-related complications, whereas nine cats (5.4%) experienced drug-delivery complications. The only factor associated with an increased risk of complications was the amount of a single dose of LA delivered through the catheter (P <0.001). An amount higher than 2.5 ml of LA delivered at each administration was associated with an increased risk of complications. All complications were minor and self-limiting. CONCLUSIONS AND RELEVANCE: WICs were used for a large variety of surgical procedures with different protocols of LA administration as part of a multimodal analgesic plan in cats. The risk of complications was relatively low and self-limiting, suggesting its safe use in cats. Further prospective studies are required to evaluate efficacy of postoperative analgesia and to determine the suitable protocol for WIC handling and maintenance.


Assuntos
Anestesia Local , Anestésicos Locais , Gatos , Animais , Estudos Retrospectivos , Anestesia Local/veterinária , Catéteres , Hospitais Veterinários
18.
Animals (Basel) ; 12(16)2022 Aug 17.
Artigo em Inglês | MEDLINE | ID: mdl-36009701

RESUMO

The aim of this study is to report outcomes of dogs undergoing cholecystectomy for gall bladder mucocele (GBM) without flushing and catheterization of the common bile duct (CBD). This is a retrospective multicentric study from three veterinary referral hospitals and included 82 dogs diagnosed with GBM. Medical records were reviewed for clinical and histopathological findings. Long-term outcome was assessed with an owner questionnaire. The common bile duct was considered normal (<4 mm), mildly dilated (5−6 mm) and moderately dilated (>7 mm) in 88%, 10% and 2.4% of dogs, respectively. Surgery was uncomplicated in 83% of dogs. Intraoperative complications were recorded in 21% of dogs, with hypotension being the most common, whereas postoperative complications were documented in 20% of dogs, with vomiting/regurgitation being the most common. Ninety-six percent of dogs that underwent cholecystectomy in this study survived to discharge. Follow-up ranged from 142 to 3930 days (median: 549 days). Eighty-five percent of dogs were alive at the time of follow-up. Dogs undergoing cholecystectomy for GBM without catheterization and flushing of the CBD have a favourable prognosis for recovery and quality of life.

19.
J Feline Med Surg ; 24(10): 1072-1080, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-34719995

RESUMO

CASE SERIES SUMMARY: Lung lobe torsion is rare in cats. The aim of this multi-institution retrospective study was to describe clinical and diagnostic findings, treatments and outcomes of lung lobe torsion (LLT) in 10 cats. Dyspnoea and tachypnoea were the most common clinical signs. Pleural effusion was present in nine cats at presentation. Fluid analysis confirmed chylothorax in three cats. Nine cats underwent CT and five cats had thoracic radiographs taken. A diagnosis was made preoperatively in six cats, while in the other four cats it was made at exploratory thoracotomy. Affected lung lobes were the right cranial (n = 4/11), left cranial (n = 4/11) and right middle (n = 3/11). One cat had a concurrent torsion of two lung lobes. Lung lobectomy was successfully performed in all cases. Based on clinical, diagnostic and lung histopathology findings, three cats had idiopathic and seven cats secondary LLT. Intraoperative complications included hypotension and hypothermia in four and five cats, respectively. Postoperative complications occurred in six cats and lead to euthanasia or death in four cats, whereas complications resolved in the other two cats. Three cats were euthanased within 5 weeks of discharge. For the three cats surviving long term, including one euthanased at 252 days postoperatively, owner-described outcomes and quality of life were considered good to excellent. RELEVANCE AND NOVEL INFORMATION: Secondary LLT associated with underlying thoracic pathology was associated with high complication rates and poor outcomes. Long-term outcomes of cats undergoing surgery for LLT and surviving the perioperative period were deemed good to excellent.


Assuntos
Doenças do Gato , Pneumopatias , Neoplasias Pulmonares , Animais , Doenças do Gato/diagnóstico , Doenças do Gato/patologia , Doenças do Gato/cirurgia , Gatos , Pulmão/diagnóstico por imagem , Pulmão/cirurgia , Pneumopatias/veterinária , Neoplasias Pulmonares/patologia , Neoplasias Pulmonares/veterinária , Qualidade de Vida , Estudos Retrospectivos , Anormalidade Torcional/etiologia , Anormalidade Torcional/cirurgia , Anormalidade Torcional/veterinária
20.
J Am Vet Med Assoc ; 261(1): 1-8, 2022 06 03.
Artigo em Inglês | MEDLINE | ID: mdl-35905164

RESUMO

OBJECTIVE: To assess the prevalence of bronchial wall thickening (BWT) and collapse in brachycephalic dogs with and without brachycephalic obstructive airway syndrome (BOAS) and in nonbrachycephalic dogs. ANIMALS: 85 dogs with no history of lower respiratory tract disease that underwent CT of the thorax. PROCEDURES: Electronical medical records for March 2011 through August 2019 were reviewed to identify brachycephalic dogs with BOAS (BOAS group) and brachycephalic dogs without BOAS (BDWB group) that did not have any evidence of lower respiratory tract disease and had undergone thoracic CT. A population of nonbrachycephalic dogs of similar weight (control dogs) was also retrospectively recruited. RESULTS: BWT was identified in 28 of 30 (93.3%; 95% CI, 80.3% to 98.6%) dogs in the BOAS group, 15 of 26 (57.7%; 95% CI, 38.7% to 75.0%) dogs in the BDWB group, and 10 of 28 (35.7%; 95% CI, 20.1% to 54.2%) control dogs. On multivariable analysis, only brachycephalic conformation (P < 0.01) and body weight (P = 0.02) were significantly associated with the presence of BWT. Bronchial collapse was identified in 17 of 30 (56.7%; 95% CI, 39.0% to 73.1%) dogs in the BOAS group, 17 of 26 (65.4%; 95% CI, 46.3% to 81.3%) dogs in the BDWB group, and 3 of 28 (10.7%; 95% CI, 3.1% to 25.9%) control dogs. On multivariable analysis, only brachycephalic conformation was significantly (P < 0.01) associated with the presence of bronchial collapse. CLINICAL RELEVANCE: A relationship between brachycephalic conformation and body weight with BWT was established, with heavier dogs having thicker bronchial walls. However, further studies are required to investigate the cause. Bronchial collapse was also more common in dogs with brachycephalic conformation, which is in agreement with the previously published literature.


Assuntos
Obstrução das Vias Respiratórias , Craniossinostoses , Doenças do Cão , Cães , Animais , Estudos Retrospectivos , Prevalência , Doenças do Cão/diagnóstico por imagem , Doenças do Cão/epidemiologia , Craniossinostoses/complicações , Craniossinostoses/epidemiologia , Craniossinostoses/veterinária , Obstrução das Vias Respiratórias/epidemiologia , Obstrução das Vias Respiratórias/veterinária , Síndrome , Peso Corporal
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