Detalhe da pesquisa
1.
Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPß levels in cerebrospinal fluid and 2D/3D cell culture models.
Neurobiol Dis
; 182: 106140, 2023 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37120095
2.
Deficient neurotransmitter systems and synaptic function in frontotemporal lobar degeneration-Insights into disease mechanisms and current therapeutic approaches.
Mol Psychiatry
; 27(3): 1300-1309, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34799692
3.
C9orf72 hexanucleotide repeat expansion leads to altered neuronal and dendritic spine morphology and synaptic dysfunction.
Neurobiol Dis
; 162: 105584, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34915153
4.
GFAP as a biomarker in frontotemporal dementia and primary psychiatric disorders: diagnostic and prognostic performance.
J Neurol Neurosurg Psychiatry
; 92(12): 1305-1312, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34187866
5.
Expression of C9orf72 hexanucleotide repeat expansion leads to formation of RNA foci and dipeptide repeat proteins but does not influence autophagy or proteasomal function in neuronal cells.
Biochim Biophys Acta Mol Cell Res
; 1868(7): 119021, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33775797
6.
FTLD Patient-Derived Fibroblasts Show Defective Mitochondrial Function and Accumulation of p62.
Mol Neurobiol
; 58(11): 5438-5458, 2021 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-34328616
7.
A Novel Genetic Marker for the C9orf72 Repeat Expansion in the Finnish Population.
J Alzheimers Dis
; 83(3): 1325-1332, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34397416
8.
Frontotemporal dementia: a conference report from the 2nd FinFTD Symposium.
Neurodegener Dis Manag
; 10(3): 119-123, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32552461
9.
BV-2 Microglial Cells Overexpressing C9orf72 Hexanucleotide Repeat Expansion Produce DPR Proteins and Show Normal Functionality but No RNA Foci.
Front Neurol
; 11: 550140, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-33123074
10.
Extracellular prolyl oligopeptidase derived from activated microglia is a potential neuroprotection target.
Basic Clin Pharmacol Toxicol
; 124(1): 40-49, 2019 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-29998529
11.
C9orf72 Proteins Regulate Autophagy and Undergo Autophagosomal or Proteasomal Degradation in a Cell Type-Dependent Manner.
Cells
; 8(10)2019 10 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31658762
12.
Astrocytes and Microglia as Potential Contributors to the Pathogenesis of C9orf72 Repeat Expansion-Associated FTLD and ALS.
Front Neurosci
; 13: 486, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31156371