Developing a Comprehensive Cardio-Oncology Program at a Cancer Institute: The Moffitt Cancer Center Experience.

Cardio-oncology is a multidisciplinary field focusing on the management and prevention of cardiovascular complications in cancer patients and survivors. While the initial focus of this specialty was on heart failure associated with anthracycline use, novel anticancer agents are increasingly utilized and are associated with many other cardiotoxicities including hypertension, arrhythmias and vascular disease. Since its inception, the field has developed at a rapid pace with the establishment of programs at many major academic institutions and community practices. Given the complexities of this patient population, it is important for providers to possess knowledge of not only cardiovascular disease but also cancer subtypes and their specific therapeutics. Developing a cardio-oncology program at a stand-alone cancer center can present unique opportunities and challenges when compared to those affiliated with other institutions including resource allocation, cardiovascular testing availability and provider education. In this review, we present our experiences establishing the cardio-oncology program at Moffitt Cancer Center and provide guidance to those individuals interested in developing a program at a similar independent cancer institution.

Comparison of temporal artery, rectal and esophageal core temperatures in children: Results of a pilot study.

BACKGROUND: Rectal thermometry correlates with core temperature and represents the criterion standard of measuring temperatures in young children. However, it has numerous disadvantages, and thus, an alternative method of measuring temperature with similar agreement with the core temperature as rectal thermometry is desired. A new, noninvasive temporal artery (TA) thermometer synthesizes the skin surface and ambient temperatures to produce an arterial temperature. OBJECTIVE: To examine the agreement between the TA and esophageal core thermometers, and to compare it with that between rectal and esophageal temperatures. METHODS: In the present prospective, cross-sectional agreement study, intubated surgical outpatients younger than 18 years of age had temperatures measured with esophageal and rectal probes, and rectal electronic and TA thermometers. The agreement between esophageal versus rectal and TA thermometers was analyzed by intraclass correlation coefficients and by differences between esophageal versus TA and rectal temperatures with 95% CIs. The esophageal-rectal and esophageal-TA slopes were compared by Student's t test. RESULTS: In 80 enrolled children, the intraclass correlation coefficients for the esophageal probe versus rectal probe, rectal electronic thermometer and TA thermometer were 0.91, 0.95 and 0.88, respectively. The mean esophageal-rectal difference was 0.00+/-0.18 degrees C and esophageal-TA difference was 0.14+/-0.20 degrees C. Linear regression analysis of the relation between esophageal probe versus rectal probe, rectal thermometer and TA thermometer yielded slopes of 0.93, 0.94 and 0.89, respectively. The slopes were neither different from each other (P=0.70) nor from the value of 1. CONCLUSION: The TA and esophageal thermometers agree well, and the esophageal-TA and esophageal-rectal temperature agreements are not significantly different.