Detalhe da pesquisa
1.
Efficacy of SPR720 in murine models of non-tuberculous mycobacterial pulmonary infection.
J Antimicrob Chemother
; 79(4): 875-882, 2024 Apr 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38394463
2.
In Vitro and In Vivo Characterization of Tebipenem, an Oral Carbapenem.
Antimicrob Agents Chemother
; 64(8)2020 07 22.
Artigo
Inglês
| MEDLINE | ID: mdl-32423950
3.
In Vitro Activity of Tebipenem (SPR859) against Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30718255
4.
Antimicrobial Activity Evaluation of Tebipenem (SPR859), an Orally Available Carbapenem, against a Global Set of Enterobacteriaceae Isolates, Including a Challenge Set of Organisms.
Antimicrob Agents Chemother
; 63(6)2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30936096
5.
In Vitro Susceptibility Testing of a Novel Benzimidazole, SPR719, against Nontuberculous Mycobacteria.
Antimicrob Agents Chemother
; 62(11)2018 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30126964
6.
Dysregulation of mprF and dltABCD expression among daptomycin-non-susceptible MRSA clinical isolates.
J Antimicrob Chemother
; 71(8): 2100-4, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27121398
7.
Frequency and Distribution of Single-Nucleotide Polymorphisms within mprF in Methicillin-Resistant Staphylococcus aureus Clinical Isolates and Their Role in Cross-Resistance to Daptomycin and Host Defense Antimicrobial Peptides.
Antimicrob Agents Chemother
; 59(8): 4930-7, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-26055370
8.
Causal role of single nucleotide polymorphisms within the mprF gene of Staphylococcus aureus in daptomycin resistance.
Antimicrob Agents Chemother
; 57(11): 5658-64, 2013 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-24002096
9.
LC-MS/MS characterization of phospholipid content in daptomycin-susceptible and -resistant isolates of Staphylococcus aureus with mutations in mprF.
Mol Membr Biol
; 29(1): 1-8, 2012 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-22276671
10.
VraSR two-component regulatory system contributes to mprF-mediated decreased susceptibility to daptomycin in in vivo-selected clinical strains of methicillin-resistant Staphylococcus aureus.
Antimicrob Agents Chemother
; 56(1): 92-102, 2012 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-21986832
11.
Regulation of mprF by antisense RNA restores daptomycin susceptibility to daptomycin-resistant isolates of Staphylococcus aureus.
Antimicrob Agents Chemother
; 55(1): 364-7, 2011 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-20974866
12.
In vitro cross-resistance to daptomycin and host defense cationic antimicrobial peptides in clinical methicillin-resistant Staphylococcus aureus isolates.
Antimicrob Agents Chemother
; 55(9): 4012-8, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21709105
13.
Potentiation of Antibiotics against Gram-Negative Bacteria by Polymyxin B Analogue SPR741 from Unique Perturbation of the Outer Membrane.
ACS Infect Dis
; 6(6): 1405-1412, 2020 06 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31566948
14.
Evaluation of Antimicrobial Effects of a New Polymyxin Molecule (SPR741) When Tested in Combination with a Series of ß-Lactam Agents Against a Challenge Set of Gram-Negative Pathogens.
Microb Drug Resist
; 26(4): 319-328, 2020 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-31596663
15.
Analysis of cell membrane characteristics of in vitro-selected daptomycin-resistant strains of methicillin-resistant Staphylococcus aureus.
Antimicrob Agents Chemother
; 53(6): 2312-8, 2009 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-19332678
16.
Characterization of SPR994, an Orally Available Carbapenem, with Activity Comparable to Intravenously Administered Carbapenems.
ACS Infect Dis
; 4(10): 1436-1438, 2018 10 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30118209
17.
Shared Platform for Antibiotic Research and Knowledge: A Collaborative Tool to SPARK Antibiotic Discovery.
ACS Infect Dis
; 4(11): 1536-1539, 2018 11 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30240184
18.
Bioanalysis of Pseudomonas aeruginosa alkyl quinolone signalling molecules in infected mouse tissue using LC-MS/MS; and its application to a pharmacodynamic evaluation of MvfR inhibition.
J Pharm Biomed Anal
; 139: 44-53, 2017 May 30.
Artigo
Inglês
| MEDLINE | ID: mdl-28273650
19.
Impact of daptomycin resistance on Staphylococcus aureus virulence.
Virulence
; 6(2): 127-31, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25830650
20.
Additional routes to Staphylococcus aureus daptomycin resistance as revealed by comparative genome sequencing, transcriptional profiling, and phenotypic studies.
PLoS One
; 8(3): e58469, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23554895