Detalhe da pesquisa
1.
An integrated disease/pharmacokinetic/pharmacodynamic model suggests improved interleukin-21 regimens validated prospectively for mouse solid cancers.
PLoS Comput Biol
; 7(9): e1002206, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-22022259
2.
Endogenous IL-21 restricts CD8+ T cell expansion and is not required for tumor immunity.
J Immunol
; 183(11): 7326-36, 2009 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19915059
3.
The combination of IL-21 and IFN-alpha boosts STAT3 activation, cytotoxicity and experimental tumor therapy.
Mol Immunol
; 46(5): 812-20, 2009 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-18947877
4.
Optimising streptozotocin dosing to minimise renal toxicity and impairment of stomach emptying in male 129/Sv mice.
Lab Anim
; 54(4): 341-352, 2020 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-31510860
5.
In vivo antitumor efficacy of interleukin-21 in combination with chemotherapeutics.
Cytokine
; 48(3): 231-8, 2009 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-19709902
6.
Nephropathy in diabetic db/db mice is accelerated by high protein diet and improved by the SGLT2 inhibitor dapagliflozin.
Eur J Pharmacol
; 860: 172537, 2019 Oct 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31310751
7.
Softened food reduces weight loss in the streptozotocin-induced male mouse model of diabetic nephropathy.
Lab Anim
; 52(4): 373-383, 2018 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-29301443
8.
Evaluating IL-21 as a Potential Therapeutic Target in Crohn's Disease.
Gastroenterol Res Pract
; 2018: 5962624, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29849593
9.
Antibody-mediated targeting of the Orai1 calcium channel inhibits T cell function.
PLoS One
; 8(12): e82944, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24376610
10.
Intratumoral interleukin-21 increases antitumor immunity, tumor-infiltrating CD8+ T-cell density and activity, and enlarges draining lymph nodes.
J Immunother
; 33(3): 236-49, 2010 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-20445344
11.
Interleukin 21 therapy increases the density of tumor infiltrating CD8+ T cells and inhibits the growth of syngeneic tumors.
Cancer Immunol Immunother
; 56(9): 1417-28, 2007 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-17285290