Detalhe da pesquisa
1.
A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer.
Proc Natl Acad Sci U S A
; 121(4): e2318093121, 2024 Jan 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38232291
2.
p66ShcA functions as a contextual promoter of breast cancer metastasis.
Breast Cancer Res
; 22(1): 7, 2020 01 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31941526
3.
p66ShcA promotes malignant breast cancer phenotypes by alleviating energetic and oxidative stress.
Redox Biol
; 70: 103028, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38211442
4.
STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer.
Nat Commun
; 12(1): 3299, 2021 06 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34083537
5.
Integration of Distinct ShcA Signaling Complexes Promotes Breast Tumor Growth and Tyrosine Kinase Inhibitor Resistance.
Mol Cancer Res
; 16(5): 894-908, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29453318
6.
Interplay between ShcA Signaling and PGC-1α Triggers Targetable Metabolic Vulnerabilities in Breast Cancer.
Cancer Res
; 78(17): 4826-4838, 2018 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29930100
7.
The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression.
Nat Commun
; 8: 14638, 2017 03 09.
Artigo
Inglês
| MEDLINE | ID: mdl-28276425
8.
Tungsten targets the tumor microenvironment to enhance breast cancer metastasis.
Toxicol Sci
; 143(1): 165-77, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25324207
9.
p66ShcA promotes breast cancer plasticity by inducing an epithelial-to-mesenchymal transition.
Mol Cell Biol
; 34(19): 3689-701, 2014 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25071152
10.
The ShcA PTB domain functions as a biological sensor of phosphotyrosine signaling during breast cancer progression.
Cancer Res
; 73(14): 4521-32, 2013 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23695548