Detalhe da pesquisa
1.
Identification of a Novel Keto Sugar Component in Streptococcus pneumoniae Serotype 12F Capsular Polysaccharide and Impact on Vaccine Immunogenicity.
J Immunol
; 210(6): 764-773, 2023 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36723033
2.
pH-dependent vesicle fusion induced by the ectodomain of the human immunodeficiency virus membrane fusion protein gp41: Two kinetically distinct processes and fully-membrane-associated gp41 with predominant ß sheet fusion peptide conformation.
Biochim Biophys Acta
; 1848(1 Pt B): 289-98, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25078440
3.
Flow-NMR as a Process-Monitoring Tool for mRNA IVT Reaction.
J Pharm Sci
; 113(4): 900-905, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38008177
4.
Comprehensive characterization of higher order structure changes in methionine oxidized monoclonal antibodies via NMR chemometric analysis and biophysical approaches.
MAbs
; 16(1): 2292688, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38117548
5.
HIV gp41 six-helix bundle constructs induce rapid vesicle fusion at pH 3.5 and little fusion at pH 7.0: understanding pH dependence of protein aggregation, membrane binding, and electrostatics, and implications for HIV-host cell fusion.
Eur Biophys J
; 40(4): 489-502, 2011 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-21222118
6.
Hairpin folding of HIV gp41 abrogates lipid mixing function at physiologic pH and inhibits lipid mixing by exposed gp41 constructs.
Biochemistry
; 48(12): 2714-22, 2009 Mar 31.
Artigo
Inglês
| MEDLINE | ID: mdl-19222185
7.
Functional and structural characterization of HIV-1 gp41 ectodomain regions in phospholipid membranes suggests that the fusion-active conformation is extended.
J Mol Biol
; 364(5): 1103-17, 2006 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-17045292
8.
The HIV fusion peptide adopts intermolecular parallel beta-sheet structure in membranes when stabilized by the adjacent N-terminal heptad repeat: a 13C FTIR study.
J Mol Biol
; 350(4): 790-805, 2005 Jul 22.
Artigo
Inglês
| MEDLINE | ID: mdl-15964015
9.
How structure correlates to function for membrane associated HIV-1 gp41 constructs corresponding to the N-terminal half of the ectodomain.
J Mol Biol
; 333(1): 47-58, 2003 Oct 10.
Artigo
Inglês
| MEDLINE | ID: mdl-14516742
10.
The stability of the intact envelope glycoproteins is a major determinant of sensitivity of HIV/SIV to peptidic fusion inhibitors.
J Mol Biol
; 340(1): 9-14, 2004 Jun 25.
Artigo
Inglês
| MEDLINE | ID: mdl-15184018
11.
REDOR solid-state NMR as a probe of the membrane locations of membrane-associated peptides and proteins.
J Magn Reson
; 253: 154-65, 2015 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-25797012
12.
Solid-state NMR spectroscopy of the HIV gp41 membrane fusion protein supports intermolecular antiparallel ß sheet fusion peptide structure in the final six-helix bundle state.
J Mol Biol
; 426(5): 1077-94, 2014 Mar 06.
Artigo
Inglês
| MEDLINE | ID: mdl-24246500
13.
Comparative analysis of membrane-associated fusion peptide secondary structure and lipid mixing function of HIV gp41 constructs that model the early pre-hairpin intermediate and final hairpin conformations.
J Mol Biol
; 397(1): 301-15, 2010 Mar 19.
Artigo
Inglês
| MEDLINE | ID: mdl-20080102
14.
Characterization of the HIV N-terminal fusion peptide-containing region in context of key gp41 fusion conformations.
J Biol Chem
; 281(31): 21755-21762, 2006 Aug 04.
Artigo
Inglês
| MEDLINE | ID: mdl-16751188
15.
The role of the N-terminal heptad repeat of HIV-1 in the actual lipid mixing step as revealed by its substitution with distant coiled coils.
Biochemistry
; 44(15): 5853-61, 2005 Apr 19.
Artigo
Inglês
| MEDLINE | ID: mdl-15823044
16.
The HIV-1 gp41 N-terminal heptad repeat plays an essential role in membrane fusion.
Biochemistry
; 41(14): 4678-85, 2002 Apr 09.
Artigo
Inglês
| MEDLINE | ID: mdl-11926830
17.
The C- and the N-terminal regions of glycoprotein 41 ectodomain fuse membranes enriched and not enriched with cholesterol, respectively.
J Biol Chem
; 279(18): 18526-34, 2004 Apr 30.
Artigo
Inglês
| MEDLINE | ID: mdl-14981088