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1.
Microsurgery ; 44(5): e31189, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38798132

RESUMO

BACKGROUND: The pure skin perforator (PSP) flap is gaining popularity for its remarkable thinness. The subdermal dissection technique was recently introduced, allowing for a quicker elevation of a PSP flap. In this report, we present our two-year experience utilizing subdermal dissection for harvesting PSP flaps. METHODS: All patients who had undergone PSP flap reconstruction at our hospital from February 2021 to February 2023 were included. Demographic data, intraoperative variables, flap characteristics, and postoperative outcomes were collected. Surgical planning involved locating the perforator using ultrasound and harvesting the flap using the subdermal dissection technique. RESULTS: A total of 26 PSP flap reconstructions were conducted on 24 patients aged between 15 and 86 years. The flaps were based on perforators issuing from the superficial circumflex iliac artery in 24 cases, and from the descending branch of the lateral circumflex femoral artery in 2 cases. Flap sizes ranged from 3 × 1.5 cm to 19 × 6 cm, with a mean thickness of 3.48 mm. The average time for flap harvest was 131.92 min. Postoperatively, we observed four cases of partial necrosis, 1 total flap loss, and 2 instances of vascular thrombosis at the anastomosis site. The flaps exhibited good pliability without contracture, and no debulking procedures were required during the follow-up period (minimum 6 months, range 6-24; mean 9.4615). CONCLUSION: The subdermal dissection technique is a safe and efficient approach for elevating PSP flaps. Our initial experience with this technique has been encouraging, and it currently serves as our preferred reconstructive option for defects requiring thin reconstruction.


Assuntos
Queimaduras , Retalho Perfurante , Procedimentos de Cirurgia Plástica , Humanos , Retalho Perfurante/irrigação sanguínea , Retalho Perfurante/transplante , Adulto , Pessoa de Meia-Idade , Masculino , Feminino , Idoso , Adolescente , Procedimentos de Cirurgia Plástica/métodos , Idoso de 80 Anos ou mais , Adulto Jovem , Queimaduras/cirurgia , Estudos Retrospectivos , Dissecação/métodos , Resultado do Tratamento , Transplante de Pele/métodos
2.
Plast Reconstr Surg Glob Open ; 12(6): e5886, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38859806

RESUMO

Background: In deep burns, the gold standard of treatment is surgical debridement and coverage, but in hands, this may lead to poor aesthetic and functional results due to the complexity of this anatomical area. Enzymatic debridement (Nexobrid) allows for the preservation of the dermal remnant and reduces the number of skin grafts when compared with surgical excision. The study aimed to analyze the patients with intermediate second-degree or deeper burns in hands who required surgical treatment after Nexobrid and those who avoided it. Methods: A descriptive retrospective study of all patients who underwent Nexobrid following hand burns between May 2015 and April 2020 treated in Vall d'Hebrón University Hospital was conducted. After the enzymatic debridement, the burn unit team determined if the burn required conservative treatment or surgery, based on the characteristics of the wound bed. Results: A total of 202 hands were collected. Most hands included in this study had deep second-degree burns (122; 60.4%). Almost half of the hands underwent surgery (99; 49%), and most had deep second-degree burns (61; 61.62%). During follow-up, 24 hands required surgery for sequelae (11.88%) and 62 did not undergo follow-up (30.69%). In the group that needed sequelae surgery, 21 needed surgery after Nexobrid and three of them were healed with conservative treatment after Nexobrid (P < 0.001). Conclusions: Nexobrid decreases the number of surgical procedures in deep burns of the hand because more conservative attitudes are adopted. Also, it seems to reduce the need of surgery due to burn sequelae.

3.
Artigo em Inglês | MEDLINE | ID: mdl-35270365

RESUMO

The impact of assisted reproduction techniques (ART) when starting to breastfeed is an important issue that has been sparsely addressed in scientific literature and yet has contradictory results. This study aims to determine the relation between the mode of fertilization and breastfeeding by means of a retrospective longitudinal cohort study that included newborns and mothers who gave birth between 2012 and 2019 in a third-level regional hospital. Data were collected from a total of 11,285 women and newborns, of which 302 (2.6%) used ART. Logistic regression was used to establish models that determine the administration of exclusive breastfeeding (BF). Among the 1208 analyzed participants, 30% conceived using fertility treatment. In this group of participants, BF was less prevalent, both in the delivery room (25.8% versus 45.5%; p < 0.001) and when discharged from hospital (42.1% versus 57.9%; p < 0.001). Healthy newborns and BF in the delivery room were predictors of BF when discharged. On the other hand, the use of ART, an Apgar score lower than 7 at birth, the use of an epidural and a premature or underweight baby are considered negative predictors of exclusive BF when discharged. It is necessary to offer greater support for all mothers regarding BF, especially those who have conceived through ART, even more so in those cases that involve an epidural and/or caesarean section, starting throughout the dilation process.


Assuntos
Aleitamento Materno , Cesárea , Feminino , Humanos , Lactente , Recém-Nascido , Estudos Longitudinais , Mães , Gravidez , Reprodução , Estudos Retrospectivos
4.
Animals (Basel) ; 12(23)2022 Dec 05.
Artigo em Inglês | MEDLINE | ID: mdl-36496945

RESUMO

Europe calls for the end to fisheries discards, which means bringing all caught fish (subject to minimum sizes or quotas) to land. This decision is beneficial to the ecosystem, since it forces the selectivity of the fishing gears to improve. However, artisanal fishermen find themselves in a vulnerable situation where their subsistence depends on catches with small profit margins. An exemption to this landing obligation exists, as it is also ruled that those animals whose survival is scientifically guaranteed may be returned to the sea. Here we study the survival of Plectorhinchus mediterraneus captured by hookline and gillnet, as well as their physiological recovery. Survival exceeds 93% in both cases. The physiological assessment of primary (cortisol) and secondary (energy mobilization, acid-base and hydromineral balance, and immune system) stress responses indicates that surviving animals are able to recover after fishing. Thus, we propose the optimal size of capture of this species to achieve greater economic benefit. For this, we rely on the prices according to size in recent years, as well as on the growth curves of the species. In this way, by releasing fish of less than 1 kg, the current benefits could be multiplied between 2.3 and 9.6 times. This pilot study lays the groundwork for regulating artisanal fisheries through scientific data related to survival of discards along with information on the sale prices.

5.
Burns ; 48(3): 577-584, 2022 05.
Artigo em Inglês | MEDLINE | ID: mdl-34844816

RESUMO

BACKGROUND: Current scientific evidence on the effect of Extracorporeal Shock Wave Therapy (ESWT) as adjunctive treatment for burn scars is scarce. However preliminary evidence, indicates it might prove a useful tool. MATERIALS AND METHODS: A prospective, randomized, controlled study was conducted from February 2017 to February 2019. Patients with burn scars were divided into two groups with twenty patients per group. The control group received the standard treatment for burn scars. The ESWT group received the standard treatment and treatment of burn scars with ESWT 512 impulses of 0.15mJ/mm2 in each session, twice per week for 4 weeks. We assessed the appearance of scar with the Vancouver Scar Scale (VSS), pruritus and pain with Visual Analog Scale (VAS) before the start of the treatment and at 2 weeks and 5 months after the treatment. RESULTS: Both groups showed improvements in all variables through the study. However, these improvements were only statistically significant for the VSS at the 6th month for the control group and VSS and VAS pain and pruritus for the ESWT group. Nonetheless the results failed to show statistically significant differences between the ESWT and the control group neither at two weeks after treatment nor at 5 months after treatment. CONCLUSION: Our study questions the relevance of ESWT as adjunctive treatment for burn scars as far as outward appearance, pain and pruritus as end-results are concern. Nonetheless, further studies are required to accurately assess the potential benefits of ESWT as an adjunctive treatment for burn scars.


Assuntos
Queimaduras , Tratamento por Ondas de Choque Extracorpóreas , Queimaduras/complicações , Queimaduras/terapia , Cicatriz/etiologia , Cicatriz/terapia , Tratamento por Ondas de Choque Extracorpóreas/métodos , Humanos , Dor/etiologia , Estudos Prospectivos , Prurido/etiologia , Prurido/terapia , Resultado do Tratamento
6.
Burns ; 48(1): 228-233, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-33858713

RESUMO

BACKGROUND: The worldwide coronavirus disease 2019 (COVID-19) epidemic, caused by the SARS-CoV-2 coronavirus, is the defining global health crisis of our time. Spain has had one of the highest burdens of COVID-19 worldwide. During this period, Vall d'Hebron University Hospital Burn Center (Barcelona) has faced a unique challenge: supporting the hospital response against COVID whilst continued offering an optimal care to the burn patient. OBJECTIVE: The aim of this study is to characterize the clinical and epidemiological characteristics of acute burn patients who received urgent health care or admission to the our Burn Center during the mandatory confinement period in Spain forced by the COVID-19 epidemic. METHODS: We analyzed the medical records of burn patients who received urgent care and/or admission to our Burn Center during the mandatory confinement period in Spain (Period 1: from March 14th to May 9th, 2020) and during the same period of the last year (Period 2: from March 14th to May 9th, 2019). Both groups were compared in order to find differences in the epidemiologic profile of burned patients. RESULTS: A total of 350 burns cases were analyzed. A 36% reduction in the number of emergency department visits was identified during Period 1. However, we found an increase in the rate of hospital admissions in Period 1 (20% of the burn cases) compared with Period 2 (13% of the burn cases). Seventy-six burn-related primary admissions were analyzed: 37 patients were admitted during Period 1 and 39 patients during Period 2. No differences were found between the two periods in the proportion of patients that underwent surgical treatment: 59.5% of patients admitted during Period 1 and 61.5% of patients admitted during Period 2. A statistically significant increase was noted in the rate of paediatric (aged 0-16 years old) admissions during Period 1 (40.54%, n = 15) compared to Period 2 (20.5%, n = 8). Among paediatric patients, an increase in the rate of surgical procedures was noted in Period 1 (47% of children), compared with Period 2 (37% of children). Proportion of patients that were admitted to the Intensive Care Unit was higher among burn children admitted during period 1 (46.7%, n = 7) than those admitted during Period 2 (25%, n = 2). Among the 37 patients admitted during the lockdown period, two positive COVID-19 patients were confirmed. CONCLUSIONS: This study gives an overview of the clinical and epidemiologic profile of burned patients during the stringent lockdown in Spain forced by the COVID-19 epidemic. Our data shows a stable trend in the number of burn-related admissions and burn related-surgeries during the confinement period. A significant increase in the rate of burn children admitted and an increase in the severity of injuries in this population is noted. These data must be taken in account in the development of strategies to ensure the maintenance of Burn Centers function in extremely situations such as the current epidemic. A lack of effective burn prevention campaigns in our environment has been noted and the development of focused prevention strategies is a priority.


Assuntos
Queimaduras , COVID-19 , Quarentena , Adolescente , Unidades de Queimados , Queimaduras/epidemiologia , Queimaduras/terapia , COVID-19/epidemiologia , COVID-19/prevenção & controle , Criança , Pré-Escolar , Humanos , Lactente , Recém-Nascido , Espanha/epidemiologia
7.
Int J Burns Trauma ; 12(6): 224-231, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36660262

RESUMO

INTRODUCTION: Mass burn casualty disasters present with a big challenge due to the complex multidisciplinary management of severely burned patients and the limited capacity of the specialized centers. Literature is scarce, and so is the management of these disasters with enzymatic debridement (ED). METHODS: Retrospective observational analysis of nine patients admitted to the Vall d'Hebron University Hospital Burn Center (Barcelona, Spain), as a consequence of a bell tower explosion on December 30, 2019. The patients with intermediate-deep second-degree burns, either in circumferential or affecting highly functional areas as hands, feet or face, were included in the ED group. Continuous variables are expressed as mode and standard deviation and quantitative ones as percentages. RESULTS: Fourteen people were injured after the explosion of gunpowder-containing bags in a bell tower during a cultural celebration. Nine casualties (6 men and 3 women) suffered burn injuries that required assessment and admission in our Burn Center. The mean age was 44.33 years (range 19-61 years), with burns covering a mean total body surface area (TBSA) of 15% (range 5-48% TBSA). One patient required invasive mechanical ventilation and intensive care management. Seven patients required ED, with an average debrided TBSA of 6.1% (range 3-10% TBSA). Seven out of 9 patients required at least one surgery. The average hospital stay was 23.33 days (range 2-53 days). No escharotomy was required and no patient died. CONCLUSIONS: This experience brought out the weak and strong features of our center when facing a situation that implies an important care stress. It can be useful for other Burn Centers in similar situations in the future. We found that new tools, such as ED, can be advantageous in such situations.

8.
Breastfeed Med ; 16(1): 68-74, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33226838

RESUMO

Objective: The association between assisted conception and breastfeeding outcomes has been investigated, but the women's experiences have not been fully explored. This study aimed to describe and understand the breastfeeding experience of first-time mothers who conceived using assisted reproductive treatment. Methods: A qualitative study based on Gadamer's hermeneutic phenomenology was conducted with a sample of 27 women who conceived using assisted reproductive treatment during the last 10 years. Focus group and in-depth interviews were conducted using a semistructured interview guide. The interviews' transcriptions were coded and categorized into themes and subthemes. Results: Two main themes emerged from the data analysis: (1) "the transition from infertility to motherhood," with the subthemes "infertility and decision to breastfeed," "the impact of birth experience on breastfeeding," and "hospital factors influencing breastfeeding practice"; and (2) "the reality of becoming a breastfeeding mother after assisted reproductive technology," with the subthemes "I want to breastfeed my infant," "the need for supports from others," and "when breastfeeding lasts longer than expected." Conclusion: Women who conceive by using assisted reproductive treatment experience a strong desire to breastfeed and problems such as low milk supply. Early cessation of breastfeeding provokes feelings of guilt and failure as mothers. Positive family networks and professional assistance are necessary to support breastfeeding.


Assuntos
Aleitamento Materno , Mães , Feminino , Humanos , Lactente , Parto , Gravidez , Pesquisa Qualitativa , Técnicas de Reprodução Assistida
9.
Burns ; 46(7): 1525-1532, 2020 11.
Artigo em Inglês | MEDLINE | ID: mdl-31387804

RESUMO

INTRODUCTION: Extracorporeal shock wave therapy (ESWT), first described in the eighties for the treatment of urolithiasis, has also been applied in other fields such as orthopaedics and chronic wound care. Recently it has also been used in the treatment of burns and its sequelae since several studies suggest it could be an important tool in the conservative management of these conditions. The aim of this article is to review the literature for published evidence on the use of ESWT for the treatment of acute burn patients and its sequelae and to elaborate a brief report on the current state of the matter. MATERIAL AND METHODS: We carried on a search on PUBMED database and Cochrane database with the following terms: ('burns' [title/abstract] OR 'burn' [title/abstract]) AND "shock wave" ([title/abstract]). For an optimal reporting of the studies found we followed the PRISMA statement. RESULTS: This search found 34 articles from which only 15 were actually related to the use of ESWT in burn patients. From these 15 articles, 7 involved the use of ESWT in the treatment of acute burns, 6 related to its application in post-burn scars, 1 in the treatment of heterotopic ossification and 1 was about the use of ESWT in skin-graft donor site. Except for the latter, all of them were carefully reviewed. CONCLUSION: Scientific evidence on the use of ESWT for the treatment of burn patients is weak due to the paucity of studies and their low quality. However, ESWT seems to be a promising tool in this field and therefore more high-quality trials should be conducted.


Assuntos
Queimaduras , Tratamento por Ondas de Choque Extracorpóreas , Queimaduras/terapia , Cicatriz/terapia , Humanos , Pele , Resultado do Tratamento
10.
Int J Burns Trauma ; 10(5): 191-200, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33224606

RESUMO

Lower limb salvage in severely injured burned patients with bone or tendon exposure may be a reconstructive challenge. In this cases, local or regional flaps and other more conservative therapies such as dermal substitutes and negative-pressure wound therapy are usually not available or are not good enough to solve the problem. In such situations, microsurgical reconstruction with distant flaps seems to be the best option, even though the particularities of the severe burn patient may decrease free flaps' success rate. We report the case of a patient with severe electrical injuries affecting 70% of the total body surface area who had full-thickness burns to the lower extremity with wide bone exposure and extensively drug-resistant Pseudomonas aeruginosa infection. We achieved limb salvation using rectus femoris muscle free flap plus lateral and medial gastrocnemius muscle flaps and soleus muscle flap, after two failed microsurgical coverture attempts and a long not useful periplus with conservative therapies such us negative-pressure wound therapy and dermal substitutes. After 3 years of follow-up, the patient can walk without aid, and he has recovered his social and employment situation prior to the accident.

11.
Burns ; 46(8): 1729-1736, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-31526634

RESUMO

INTRODUCTION: Burned patients may present with different type and severity of sensory dysfunction. Regenerative mechanisms in the peripheral nervous system are diminished after burn injury and thus unable to accurately regenerate somatosensitive skin receptors. The pattern by which neuronal regeneration occurs to regain this sensitivity in burn patients is still unclear. PATIENTS AND METHOD: This observational retrospective study focuses on determining the patterns of heat, heat-pain, cold, cold-pain, sympathetic skin response and touch following severe burns. Twenty-six burn patients with different type of burns were included in the study. The survey methods used included the Quantitative Sensory Test for termoalgesic measurement, electrical SSR and the Von Frey filaments for quantitative measurements of touch/pressure. RESULTS: The results showed that patients present with hypoesthesia to heat, cold, and touch in postburn skin areas compared with the contralateral healthy areas. However, in the heat-pain sensation, no hypoesthesia was noted. CONCLUSIONS: Our results suggest that burn patients have a sensitivity dysfunction in postburned skin areas. The use of QST could be considered the technique to determine the sensitivity of burned patients. Although, more high-quality studies should to be done.


Assuntos
Queimaduras/complicações , Transtornos de Sensação/etiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Queimaduras/fisiopatologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Limiar da Dor/fisiologia , Qualidade de Vida/psicologia , Estudos Retrospectivos , Tato/fisiologia
12.
Front Endocrinol (Lausanne) ; 11: 560375, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33224105

RESUMO

Insulin plays a major neuroprotective and trophic function for cerebral cell population, thus countering apoptosis, beta-amyloid toxicity, and oxidative stress; favoring neuronal survival; and enhancing memory and learning processes. Insulin resistance and impaired cerebral glucose metabolism are invariantly reported in Alzheimer's disease (AD) and other neurodegenerative processes. AD is a fatal neurodegenerative disorder in which progressive glucose hypometabolism parallels to cognitive impairment. Although AD may appear and progress in virtue of multifactorial nosogenic ingredients, multiple interperpetuative and interconnected vicious circles appear to drive disease pathophysiology. The disease is primarily a metabolic/energetic disorder in which amyloid accumulation may appear as a by-product of more proximal events, especially in the late-onset form. As a bridge between AD and type 2 diabetes, activation of c-Jun N-terminal kinase (JNK) pathway with the ensued serine phosphorylation of the insulin response substrate (IRS)-1/2 may be at the crossroads of insulin resistance and its subsequent dysmetabolic consequences. Central insulin axis bankruptcy translates in neuronal vulnerability and demise. As a link in the chain of pathogenic vicious circles, mitochondrial dysfunction, oxidative stress, and peripheral/central immune-inflammation are increasingly advocated as major pathology drivers. Pharmacological interventions addressed to preserve insulin axis physiology, mitochondrial biogenesis-integral functionality, and mitophagy of diseased organelles may attenuate the adjacent spillover of free radicals that further perpetuate mitochondrial damages and catalyze inflammation. Central and/or peripheral inflammation may account for a local flood of proinflammatory cytokines that along with astrogliosis amplify insulin resistance, mitochondrial dysfunction, and oxidative stress. All these elements are endogenous stressor, pro-senescent factors that contribute to JNK activation. Taken together, these evidences incite to identify novel multi-mechanistic approaches to succeed in ameliorating this pandemic affliction.


Assuntos
Doença de Alzheimer/metabolismo , Doença de Alzheimer/patologia , Encéfalo/metabolismo , Encéfalo/patologia , Metabolismo Energético/fisiologia , Resistência à Insulina/fisiologia , Peptídeos beta-Amiloides/metabolismo , Animais , Humanos , Estresse Oxidativo/fisiologia
13.
Burns ; 46(7): 1668-1673, 2020 11.
Artigo em Inglês | MEDLINE | ID: mdl-32553443

RESUMO

OBJECTIVE: The objective of this study is to review our experience in the implementation of an innovative Telemedicine Platform (the Teleburns Project) for the acute care of burned patients. METHODS: We developed and implemented a Teleburns Platform by the creation of a new medical software and hardware for High Definition medical videoconference, in order to assist distant burned patients. After the establishment of the system and revision of technical requirements, an internal validation of the project was done: we managed 40 consecutive burned patients via telemedicine videoconference within our own Center. Following the internal validation, a pilot test with the Verge de la Cinta Hospital (VCH) - located in Tortosa, 180km away from Barcelona - was conducted. A prospective review of 43 burn patients participating in tele-encounters was performed. The data collected were: patient and injury demographics, need for transfer to our hospital, need for surgical treatment, complications, readmissions and technical problems. RESULTS: No discrepancies were found between remote and face-to-face diagnosis and treatment during internal validation, obtaining a 100% reliability. No technical errors were reported. Concerning the pilot test with the VCH, 43 patients were assessed via telemedicine during a 48-month period. Mean age of the participants was 36.7 (0-85 years). The mean total burn surface area was 3.1% (range 0.5-15%). The more frequently affected areas were head and neck (27 patients) and hands (16 patients). As a result of the 43 televisits, 8 patients (18.6%) were immediately transferred to our Burn Center in Barcelona and 12 patients (27.9%) were asked to come a few days later, to be visited in our Day Care Unit. Thus 23 patients (53.5%) could avoid being transferred to the Burn Center. 5 of them were followed via Teleburns without complications and 17 patients were discharged after the first tele-encounter. All patients discharged presented an uneventful evolution and did not receive further care from our Burn Unit. Technical problems were reported in eleven occasions during this phase, none of which prevented completion of the visits. CONCLUSIONS: The use of Telemedicine for burn assessment can improve the accuracy of burn patients triage, resulting in enhanced resource utilization, time and cost saving for the health system and increased quality of care.


Assuntos
Queimaduras , Telemedicina , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Unidades de Queimados , Queimaduras/terapia , Criança , Pré-Escolar , Estudos de Viabilidade , Humanos , Lactente , Recém-Nascido , Pessoa de Meia-Idade , Estudos Prospectivos , Reprodutibilidade dos Testes , Espanha , Adulto Jovem
14.
Front Endocrinol (Lausanne) ; 11: 573032, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33042026

RESUMO

Diabetes is constantly increasing at a rate that outpaces genetic variation and approaches to pandemic magnitude. Skin cells physiology and the cutaneous healing response are progressively undermined in diabetes which predisposes to lower limb ulceration, recidivism, and subsequent lower extremities amputation as a frightened complication. The molecular operators whereby diabetes reduces tissues resilience and hampers the repair mechanisms remain elusive. We have accrued the notion that diabetic environment embraces preconditioning factors that definitively propel premature cellular senescence, and that ulcer cells senescence impair the healing response. Hyperglycemia/oxidative stress/mitochondrial and DNA damage may act as major drivers sculpturing the senescent phenotype. We review here historical and recent evidences that substantiate the hypothesis that diabetic foot ulcers healing trajectory, is definitively impinged by a self-expanding and self-perpetuative senescent cells society that drives wound chronicity. This society may be fostered by a diabetic archetypal secretome that induces replicative senescence in dermal fibroblasts, endothelial cells, and keratinocytes. Mesenchymal stem cells are also susceptible to major diabetic senescence drivers, which accounts for the inability of these cells to appropriately assist in diabetics wound healing. Thus, the use of autologous stem cells has not translated in significant clinical outcomes. Novel and multifaceted therapeutic approaches are required to pharmacologically mitigate the diabetic cellular senescence operators and reduce the secondary multi-organs complications. The senescent cells society and its adjunctive secretome could be an ideal local target to manipulate diabetic ulcers and prevent wound chronification and acute recidivism. This futuristic goal demands harnessing the diabetic wound chronicity epigenomic signature.


Assuntos
Senescência Celular/fisiologia , Pé Diabético/fisiopatologia , Cicatrização/fisiologia , Dano ao DNA , Humanos , Células-Tronco Mesenquimais/fisiologia , Estresse Oxidativo
15.
Cir. plást. ibero-latinoam ; 46(supl.1): S121-S132, abr. 2020. tab, ilus
Artigo em Espanhol | IBECS (Espanha) | ID: ibc-193502

RESUMO

INTRODUCCIÓN Y OBJETIVO: La Microcirugía como técnica dentro de la Cirugía Plástica no puede faltar en cualquier unidad de quemados para garantizar el tratamiento completo de sus pacientes. Sobre todo en los quemados eléctricos que presentan lesiones muy graves con exposición de tejidos nobles en los que es la primera opción reconstructiva. El objetivo de este artículo es mostrar la experiencia de la Unidad de Quemados del Hospital Universitario Vall d'Hebron de Barcelona, España, en los últimos 10 años en el uso de la Microcirugía en el paciente quemado agudo de etiología eléctrica. MATERIAL Y MÉTODO: Revisión retrospectiva de 19 colgajos realizados entre enero de 2010 y agosto de 2019 en 15 pacientes con quemaduras eléctricas, recogiendo datos de sexo, edad, localización del defecto, superficie corporal quemada (SCQ), colgajo empleado, días hasta la cobertura, tipo de anastomosis arterial, número de venas usadas, supervivencia de los colgajos y complicaciones. RESULTADOS: Destaca que los 15 pacientes fueron varones, con edad media de 36.5 años; SCQ media del 19.5%; el colgajo más usado fue el ántero-lateral de muslo con 9 casos (47.37%), seguido por el de dorsal ancho con 4 casos (21.05%), el colgajo inguinal y el de músculo recto femoral con 2 casos cada uno (10.53% en cada caso) y el de perforante tóraco-dorsal y de fascia temporal superficial con 1 caso cada uno (5.26% en cada caso). La localización más frecuente fue en extremidades inferiores con 12 casos (63.16%), seguida por las extremidades superiores con 5 casos (26.31%) y la cabeza con 2 casos (10.53%). La cirugía de cobertura con el colgajo libre se realizó de media a los 24 días. La anastomosis arterial fue término-terminal en 15 casos (79%). La anastomosis venosa fue término-terminal siempre, anastomosando 2 venas en 5 casos (26.31%) y solo 1 en el resto (73.69%). Dos colgajos fracasaron por congestión venosa (10.53%) y 2 colgajos se complicaron por infección (10.53%). CONCLUSIONES: La reconstrucción de defectos complejos tras quemadura eléctrica es un reto por el escaso número de casos que se presentan y por la propia idiosincrasia de la injuria eléctrica y del paciente quemado. El desbridamiento correcto, la selección del vaso receptor y decidir el momento óptimo para la reconstrucción son los puntos más importantes a tener en cuenta. Por estos motivos consideramos que esta patología debe ser abordada en unidades de quemados multidisciplinares con personal altamente entrenado


BACKGROUND AND OBJECTIVE: Microsurgery as a technique in Plastic Surgery cannot miss any burn ut for complete treatmeent of their patientes. Especially in electric burns that have very serious lesions with exposure of noble tissues where Microsurgery is the first reconstructive option. The objective of this paper is to show the experience of the Burn Unit of the Vall d'Hebron University Hospital in Barcelona, Spain, over the last 10 years in the application of Microsurgery in the burned patient of electrical etiology. METHODS: A total of 19 flaps performed between January 2010 and August 2019 in patients with electrical burn injury were reviewed retrospectively. The data collected were sex, age, location of the defect, total burned surface area (TBSA), flap used, days until coverage, type of arterial anastomosis, number of veins used, flap survival and complications. RESULTS: It is noteworthy that all the 15 patients treated were male, with an average age of 36.5 years; average TBSA was 19.5%; the most frequently flap used was the antero-lateral thigh in 9 cases (47.37%), followed by the latissimus dorsi muscle in 4 cases (21.05%), the inguinal and the rectus femoris muscle in 2 cases each (10.53% in each case) and the thoraco-dorsal artery perforator and the superficial temporal fascia on 1 occasion each of them (5.26% in each case). The most frequent location was in the lower extremities in 12 cases (63.16%), followed by the upper extremities in 5 cases (26.31%) and the head in 2 cases (10.53%). On average, coverage surgery with the free flap was performed at 24 days. Arterial anastomosis was performed end-to-end in 15 cases (79%). The venous anastomosis was always end-to-end anastomosing 2 veins in 5 cases (26.31%) and only 1 in the rest (76.69%). Two flaps failed due to venous congestion (10.53%) and 2 flaps were complicated with infection (10.53%). CONCLUSIONS: The reconstruction of complex defects associated with an electrical burn has been, is a challenge for plastic surgeons because of the small number of cases that occur and, because of the idiosyncrasy of the electrical injury and the burned patient. A correct debridement, the selection of the recipient vessel and deciding the optimal time for reconstruction are the most important points to consider. For these reasons we believe that this pathology should be addressed in multidisciplinary burn units with highly trained personnel


Assuntos
Humanos , Masculino , Adulto , Pessoa de Meia-Idade , Queimaduras por Corrente Elétrica/cirurgia , Microcirurgia/instrumentação , Microcirurgia/métodos , Queimaduras por Corrente Elétrica/etiologia , Estudos Retrospectivos , Retalhos de Tecido Biológico , Cicatriz/cirurgia , Autoenxertos/cirurgia
16.
Gac Sanit ; 25(6): 483-9, 2011.
Artigo em Espanhol | MEDLINE | ID: mdl-21703729

RESUMO

OBJECTIVE: To analyze first-time mothers communication with health professionals, and to explore satisfaction, needs and expectation towards healthcare services. METHOD: Qualitative design using in-deep interviews and phenomenology was used. First-time mothers from Huercal-Overa (Almería) were intentionally selected in 2010 and were included in the study. A hermeneutic analysis was performed. RESULTS: Six meta-categories were obtained. Saturation of information was found with nine interviews. The meta-categories were the following: 1) Health professionals; 2) Pregnancy, partum and postpartum; 3) Communication; 4) Child nutrition; 5) Feelings; 6) Others. The mothers perceived as exciting this new experience and expressed feelings of fear, anguish and high sensitiveness. These feelings are increased by the information received from the family circle and the professionals which is referred low and contradictory. All professionals were positively considered, specially the midwife. The following negative experiences were identified: contractions, dilation and delivery. The end of the stay at the hospital was considered early and the time for consultation was short for the mothers. There is a demand about more information on breast feeding. Mothers wish health professionals to respect their decisions. CONCLUSIONS: The study found some areas for improvement in the communication between firs-time mothers and health professionals which could be taken into account in satisfaction promotion plans in regards to healthcare services.


Assuntos
Comunicação , Hospitais Públicos , Unidade Hospitalar de Ginecologia e Obstetrícia , Satisfação do Paciente , Assistência Perinatal , Período Pós-Parto/psicologia , Relações Profissional-Paciente , Aleitamento Materno , Emoções , Feminino , Humanos , Cuidado do Lactente , Recém-Nascido , Tempo de Internação , Paridade , Educação de Pacientes como Assunto , Assistência Perinatal/organização & administração , Cuidado Pós-Natal , Gravidez , Cuidado Pré-Natal , Pesquisa Qualitativa , Espanha
17.
Gac. sanit. (Barc., Ed. impr.) ; 25(6): 483-489, nov.-dic. 2011. tab
Artigo em Espanhol | IBECS (Espanha) | ID: ibc-104215

RESUMO

Objetivo Analizar cómo perciben las primíparas su comunicación con los profesionales de la salud y explorar la satisfacción, necesidades y expectativas hacia los servicios sanitarios. Método Este estudio siguió un diseño cualitativo usando entrevistas en profundidad con metodología fenomenológica. La muestra fue de carácter intencional y estuvo compuesta por mujeres puérperas-primíparas residentes en Huércal-Overa (Almería) en 2010.ResultadosSe obtuvieron seis metacategorías. La saturación de información se consiguió con un total de nueve entrevistas. Las metacategorías fueron: 1) Profesionales de la salud; 2) Embarazo, parto y puerperio; 3) Comunicación; 4) Alimentación del neonato; 5) Sentimientos; 6) Otros. Las participantes se encuentran expectantes ante una experiencia nueva, expresando sentimientos de miedo, angustia y alta sensibilidad hacia todo. La información del círculo familiar unida a la de los profesionales, que refieren como escasa y contradictoria, contribuye a aumentar estos sentimientos. Todos los profesionales sanitarios fueron valorados positivamente. Las contracciones, la dilatación y el parto fueron las experiencias más negativas del proceso. El alta hospitalaria se vivió como temprana y el tiempo dedicado a las consultas se consideró escaso. Se demanda información y apoyo a la lactancia materna, así como mayor respeto en sus decisiones sobre como alimentar a sus bebés. Conclusiones Existen posibles áreas de mejora en la comunicación entre las primíparas y el personal sanitario, las cuales deberían tomarse en cuenta en planes de mejora de la satisfacción de las nuevas madres en relación a los servicios sanitarios que se les ofrecen(AU)


Objective To analyze first-time mothers communication with health professionals, and to explore satisfaction, needs and expectation towards healthcare services. Method Qualitative design using in-deep interviews and phenomenology was used. First-time mothers from Huercal-Overa (Almería) were intentionally selected in 2010 and were included in the study. A hermeneutic analysis was performed. Results Six meta-categories were obtained. Saturation of information was found with nine interviews. The meta-categories were the following: 1) Health professionals; 2) Pregnancy, partum and postpartum; 3) Communication; 4) Child nutrition; 5) Feelings; 6) Others. The mothers perceived as exciting this new experience and expressed feelings of fear, anguish and high sensitiveness. These feelings are increased by the information received from the family circle and the professionals which is referred low and contradictory. All professionals were positively considered, specially the midwife. The following negative experiences were identified: contractions, dilation and delivery. The end of the stay at the hospital was considered early and the time for consultation was short for the mothers. There is a demand about more information on breast feeding. Mothers wish health professionals to respect their decisions. Conclusions The study found some areas for improvement in the communication between firs-time mothers and health professionals which could be taken into account in satisfaction promotion plans in regards to healthcare services(AU)


Assuntos
Humanos , Sistemas de Comunicação no Hospital/organização & administração , Gestantes/psicologia , Aleitamento Materno/estatística & dados numéricos , Satisfação do Paciente/estatística & dados numéricos , Relações Profissional-Paciente , Pesquisa Qualitativa
18.
Rev. otorrinolaringol. cir. cabeza cuello ; 52(2): 105-8, ago. 1992. ilus
Artigo em Espanhol | LILACS | ID: lil-112278

RESUMO

Se comparan los porcentajes de detección de lesiones vestibulares en 257 exámenes de 8- par dependiendo si en estos se ha usado o no la electronistagmografía (ENG) como método complementario de estudio. Del grupo de exámenes realizados con ENG, se obtienen al azar 33 pacientes con pruebas calóricas simétricas para los parámetros duración, amplitud y frecuencia del nistagmo post calórico, pero que al analizarles posteriormente su velocidad de la componente lenta (VCL), ésta sí demuestra asimetría. A este grupo se le realiza entonces una prueba calórica bilateral simultánea a 46-C que confirma en prácticamente todos los casos lo que demostraba la VCL en la electronistagmografía


Assuntos
Humanos , Masculino , Feminino , Doenças Vestibulares/diagnóstico , Vestíbulo do Labirinto/lesões , Eletronistagmografia/métodos
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