Die oralen Auswirkungen von Morbus Crohn: Beschreibung von neun Fällen.

Crohn’s disease (CD) is a chronic inflammatory bowel disease whose oral features remain underrated at clinical examination. The aim of the study was to report forerunner orofacial presentations leading to diagnosis of CD among nine patients of mean age 23 between 2008 and 2015. Linear ulcerative buccal lesions, cobblestoning, mucosal tags and perioral erythema are highly evocative and might precede intestinal signs for several years. Oral biopsies revealed highly suggestive lesions of CD for 45% of patients before any intestinal symptom or digestive investigation. Mean time to diagnosis was 14 months. Immunomodulatory therapy (azathioprine, infliximab, adalimumab) was introduced alone or in association for 89% of patients. Early diagnosis could lead to specific therapy, often necessary to reduce severity of lesions and improve quality of life.

Orthopedic treatment of Class III malocclusions using skeletal anchorage: A bibliographical review.

AIM: To summarize scientific articles relating to orthopedic treatment using skeletal anchorage for Class III malocclusions in 2016. MATERIALS AND METHODS: Exhaustive bibliographical research on PubMed with the following keywords "bone OR skeletal-anchored maxillary protraction". RESULTS: Twenty-one articles were noted between March 2008 and August 2015. Eleven were original articles with clinical series. Two reviews of the literature, two technical, two focus articles, three clinical cases and one animal study were also published. DISCUSSION: This is the first genuinely orthopedic technique for this indication, and it may in the medium term avoid recourse to a surgical-orthodontic protocol. However, its use is compromised by the ignorance of practitioners and operators, patient refusal to accept general anesthesia and less-than-perfect materials.