Detalhe da pesquisa
1.
The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals.
Nat Immunol
; 15(9): 875-883, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-25108421
2.
Unleashing T cell responses to cancer through removal of intracellular checkpoints.
Immunol Cell Biol
; 100(1): 18-20, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34936141
3.
Anti-PD-1/anti-CTLA-4 efficacy in melanoma brain metastases depends on extracranial disease and augmentation of CD8+ T cell trafficking.
Proc Natl Acad Sci U S A
; 115(7): E1540-E1549, 2018 02 13.
Artigo
Inglês
| MEDLINE | ID: mdl-29386395
4.
Targeting the tumor microenvironment and T cell metabolism for effective cancer immunotherapy.
Eur J Immunol
; 49(8): 1147-1152, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31270810
5.
Regulation of autoimmune and anti-tumour T-cell responses by PTPN22.
Immunology
; 154(3): 377-382, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29512901
6.
Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice.
J Immunol
; 197(2): 429-40, 2016 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27288531
7.
Mechanistic Target of Rapamycin Complex 1/S6 Kinase 1 Signals Influence T Cell Activation Independently of Ribosomal Protein S6 Phosphorylation.
J Immunol
; 195(10): 4615-22, 2015 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26453749
8.
Type 2 innate lymphoid cells drive CD4+ Th2 cell responses.
J Immunol
; 192(5): 2442-8, 2014 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24470502
9.
Interleukin-33 and the function of innate lymphoid cells.
Trends Immunol
; 33(8): 389-96, 2012 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-22609147
10.
Targeting Protein Tyrosine Phosphatases to Improve Cancer Immunotherapies.
Cells
; 13(3)2024 Jan 25.
Artigo
Inglês
| MEDLINE | ID: mdl-38334623
11.
OT-I TCR Transgenic Mice to Study the Role of PTPN22 in Anti-cancer Immunity.
Methods Mol Biol
; 2743: 81-92, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38147209
12.
Systemic inflammation, the peripheral blood transcriptome and primary melanoma.
J Invest Dermatol
; 2024 Apr 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38583742
13.
Mislocalization of Lck impairs thymocyte differentiation and can promote development of thymomas.
Blood
; 117(1): 108-17, 2011 Jan 06.
Artigo
Inglês
| MEDLINE | ID: mdl-20876849
14.
IL-33 induces innate lymphoid cell-mediated airway inflammation by activating mammalian target of rapamycin.
J Allergy Clin Immunol
; 130(5): 1159-1166.e6, 2012 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-22738676
15.
T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance.
Immunol Rev
; 228(1): 9-22, 2009 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-19290918
16.
Regulation of T Cell Activation and Metabolism by Transforming Growth Factor-Beta.
Biology (Basel)
; 12(2)2023 Feb 13.
Artigo
Inglês
| MEDLINE | ID: mdl-36829573
17.
Deletion of the protein tyrosine phosphatase PTPN22 for adoptive T cell therapy facilitates CTL effector function but promotes T cell exhaustion.
J Immunother Cancer
; 11(12)2023 12 06.
Artigo
Inglês
| MEDLINE | ID: mdl-38056892
18.
The influence of mTOR on T helper cell differentiation and dendritic cell function.
Eur J Immunol
; 41(8): 2137-41, 2011 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21725971
19.
TGFß limits Myc-dependent TCR-induced metabolic reprogramming in CD8+ T cells.
Front Immunol
; 13: 913184, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35958566
20.
MAPK, phosphatidylinositol 3-kinase, and mammalian target of rapamycin pathways converge at the level of ribosomal protein S6 phosphorylation to control metabolic signaling in CD8 T cells.
J Immunol
; 183(11): 7388-97, 2009 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19917692