RESUMO
Nine diabetic and 7 nondiabetic (post-trauma) patients 24 to 63 years of age (mean, 49) were scanned following amputation below the knee, which was bilateral in 4. A three-phase scanning technique (flow, blood pool, and delayed equilibrium images) was employed, using Tc-99m-etidronate. Duration of the arterial and capillary phases was estimated during flow. Activity at the tip of the stump was plotted as a function of (a) time since amputation and (b) flow measurements. Activity was found to diminish over a period of nearly 50 months, usually becoming minimal or undetectable after 18 months. The stump demonstrated relative stasis compared to the intact limb, particularly in diabetics and patients with long-standing amputation.
Assuntos
Cotos de Amputação , Perna (Membro)/diagnóstico por imagem , Adulto , Osso e Ossos/diagnóstico por imagem , Complicações do Diabetes , Diabetes Mellitus/fisiopatologia , Humanos , Perna (Membro)/irrigação sanguínea , Perna (Membro)/cirurgia , Pessoa de Meia-Idade , Cintilografia , Fluxo Sanguíneo RegionalRESUMO
A new technique for the study of cardiac hemodynamics is described which utilizes single-breath inhalation of C15O2 (T 1/2 = 124 sec.) and the recording of activity vs. time curves with scintillation counters placed externally over the left ventricle and right lung. The results from 10 normal volunteers and 28 patients with acquired or congenital heart disease have been compared to the findings at cardiac catheterization. The technique is safe, rapid, and nontraumatic, and yielded no false positives or negatives in this series.