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1.
Mali méd. (En ligne) ; 39(1): 34-39, 2024. tables
Artigo em Inglês | AIM | ID: biblio-1554268

RESUMO

Introduction : La vaccination de routine est une stratégie clé dans la prévention des maladies évitables par la vaccination. L'objectif de l'étude est d'apprécier les connaissances, attitudes des mères vis-à-vis de la pratique de la vaccination en milieu rural et urbain. Méthodes : Il s'agit d'une étude transversale descriptive comparative qui a eu lieu dans deux aires de santé (urbaine et rurale) sur une période de trois (3) mois d'octobre à décembre 2022. Elle a concerné les mères ou gardiennes d'enfants venus pour la vaccination de routine. Résultats : La moyenne d'âge des femmes était de 28, 76±6,85 ans en milieu urbain et 26,51±7,37 ans en milieu rural. Environ72, 00% et 43,00% des femmes respectivement en milieu urbain et rural avaient donné une bonne définition de la vaccination. 88,00% des femmes en milieu urbain connaissaient au moins une maladie cible du PEV contre 55,00% en milieu rural. Le calendrier vaccinal n'était connu que par 31,00% des femmes en milieu urbain contre 12,00% en milieu rural. La majorité des femmes en milieu urbain (97,00%) et rural (67,00%) trouvaient nécessaire de rattraper un rendez-vous de vaccination manqué les séances prochaines. Elles jugeaient majoritairement d'envoyer les enfants au centre de santé en cas de manifestations post- vaccinale (urbain : 80,00%, rural : 53,00%). Conclusion : Une bonne connaissance et pratique de la vaccination permettrait ainsi de protéger les enfants contre les maladies évitables par la vaccination


Background: Routine immunization is a key strategy in the prevention of vaccine-preventable diseases. The objective of the study was to assess the knowledge and attitudes of mothers regarding the practice of vaccination in rural and urban areas. Methods: This is a comparative descriptive cross-sectional study that took place in two health areas (urban and rural) over a period of three (3) months from October to December 2022. It involved mothers or guardians of children who came for routine vaccination. Results: The mean age of the women was 28.76±6.85 years in urban areas and 26.51±7.37 years in rural areas. About 72.00% and 43.00% of the women in urban and rural areas, respectively, had given a good definition of vaccination. 88.00% of women in urban areas knew at least one EPI target disease, compared to 55.00% in rural areas. Only 31.00% of women in urban areas knew the vaccination schedule, compared to 12.00% in urban areas. Majority of women in urban (97.00%) and rural (67.00%) areas found it necessary to make up for missed immunization appointments in next sessions. Majority of them considered it necessary to send their children to the health center in the event of postimmunization symptoms (urban: 80.00%, rural: 53.00%). Conclusion: A good knowledge and practice of vaccination would allow to protect children against vaccine preventable diseases


Assuntos
Humanos , Feminino
2.
Mali Med ; 30(4): 21-25, 2015.
Artigo em Francês | MEDLINE | ID: mdl-29927130

RESUMO

This work was aimed to describe the epidemiological, clinical, biological and electrical aspects of orthostatic low blood pressure (LBP) within patients with high blood pressure (HBP) in the cardiology department of the Kati University Hospital. This was a prospective cross-sectional study conducted between June 1st, 2012 and May 31st, 2013. It included all the patients with HBP regularly assessed for at least a month, following their treatment and having no other treatments which can induce a orthostatic LBP. RESULTS: With a total of 300 subjects with high blood pressure, 42 subjects presented an orthostatic LBP with or without suggestive clinical demonstrations, among which 16 men and 26 women, with an average age of 55 year. In the HBP population, the orthostatic LBP had a 14% frequency (42/300), the sex ratio was 0.61. Most of the patients were 55 years old or more. The HBP was not controlled in 66.7% of cases. Twelve percent of the patients with orthostatic LBP were diabetics. The number of antihypertensive drug used did not appear to influence the appearance of an orthostatic LBP. Monotherapy was associated with an orthostatic LBP in 47.6% of cases and this monotherapy used the calcic inhibitors in 62% of the cases. Orthostatic low blood pressure is frequent within patient with HBP undergoing treatment. It must be systematically looked for, especially in the uncontrolled HBP, among older subjects, the diabetics, and those with a personal history of neurological disease.


OBJECTIF: Ce travail visait à décrire les aspects épidémiologiques, cliniques, biologiques et électriques de l'hypotension orthostatique chez l'hypertendu dans le service de cardiologie du CHU de Kati. PATIENTS ET MÉTHODES: L'étude était transversale et prospective allant du 1er Juin 2012 au 31 Mai 2013 dans le service de cardiologie du CHU de Kati. Il s'agissait de l'ensemble des patients hypertendus régulièrement suivis depuis un mois et plus, bien observant et n'ayant pas d'autres traitements pouvant favorisés l'hypotension orthostatique. RÉSULTATS: Au total 42 sujets présentant une hypotension orthostatique avec ou sans manifestations cliniques évocatrices ont étés inclus, dont 16 hommes et 26 femmes, en moyenne âgés de 55 ans. Dans la population d'hypertendus, l'hypotension orthostatique avait une fréquence de 14% (42/300), le sex ratio était de 0,61. Les patients âgés de plus de 55 ans étaient plus nombreux. L'hypertension artérielle n'était pas contrôlée dans 66,7%. 11,9% des patients hypotendus orthostatiques étaient diabétiques. Le nombre d'antihypertenseur utilisé ne paraissait pas influencer l'apparition d'une hypotension orthostatique. La monothérapie était associée à une hypotension orthostatique dans 47,6% et cette monothérapie utilisait les inhibiteurs calciques dans 62% des cas. CONCLUSION: L'hypotension orthostatique est fréquente chez les hypertendus traités. Elle doit être recherchée systématiquement, en particulier dans l'HTA non contrôlée, chez les sujets âgés, les diabétiques, et chez ceux ayant un antécédent neurologique.

3.
Mali Med ; 30(1): 3-6, 2015.
Artigo em Francês | MEDLINE | ID: mdl-29927149

RESUMO

OBJECTIVE: Determine the frequency of thrombosis of the upper and lower limbs in the cardiology specialist unit. Describe the clinical and paraclinical signs observed. Identify etiological factors. Evaluate the response to treatment. MATERIAL AND METHODS: This longitudinal prospective study was conducted from the 1st January 2007 to 31st May 2008 in the service of cardiology of the Gabriel Touré Teaching Hospital of Bamako. Included in the study were all the patients diagnosed with deep vein thrombosis confirmed by venous ultrasound imaging. The data was analyzed with the software Ear-information-6.04d. RESULTS: 12 cases of deep vein thrombosis confirmed for a total of 1171 hospitalizations, either of 1,88% with a high frequency between 30 and 44 years old (40,9%) without any preference of sex (sex ratio=1). 63,6% had no known cardiovascular antecedent. The clinical signs were evocative in 90 cases, 9%. Prolonged confinement was present in 59.09% of cases, and was associated with HIV infection in 18.1% of cases. The attack of the left lower limb was recorded the most (72.7%), only one case of the left upper limb (4.5%). The attack of the major network preferentially prevailed (86.3%) with preferably proximal seat (72.7%). The femoral vein was reached (50%). 86.3% of the patients received HBPM +AVK with 68.18% of cure without after-effect. The evolution was complicated by pulmonary embolism in 13.6% of cases and death in 4.5%. CONCLUSION: Deep vein thrombosis of the limbs occupies a significant place among cardiovascular pathologies in Bamako and HIV seems to increase its frequency.


OBJECTIF: Déterminer la fréquence des thromboses veineuses profondes des membres supérieurs et inferieurs dans le milieu spécialisé cardiologique. Décrire les signes cliniques et para cliniques. Identifier les facteurs étiologiques. Evaluer l'évolution sous traitement. MATÉRIEL ET MÉTHODES: Il s'agissait d'une étude prospective et longitudinale qui s'est déroulée du 1er janvier 2007 au 31 mai 2008 dans le service de cardiologie du Centre Hospitalier Universitaire Gabriel Touré de Bamako. Etaient inclus tous les patients qui présentaient une thrombose veineuse profonde des membres confirmée échographiquement. Les données ont été analysées avec le logiciel Epi-info-6.04d. RÉSULTATS: 22 cas de thrombophlébite confirmée pour un total de 1171 hospitalisations, soit une fréquence de 1,88% avec un âge de survenue entre 30 et 44ans (40,9%) sans aucune préférence de sexe (sex ratio=1). Soixante et trois virgule six pour cent n'avaient aucun antécédent cardiovasculaire connu. Les signes cliniques étaient évocateurs dans 90,9%. L'alitement prolongé était présent dans 59,09% des cas, associé à l'infection au VIH dans 18,1%. L'atteinte du membre inférieur gauche prédominait (72,7%), un seul cas du membre supérieur gauche (4,5%). L'atteinte du réseau profond prédominait (86,3%) avec un siège préférentiellement proximal (72,7%). La veine fémorale a été la plus thrombosée (50%). Quatre-vingt et six virgule trois pour cent des patients ont reçu les Héparines de Bas Poids Moléculaire (HBPM) + Anti Vitamine K (AVK) avec 68,18% de guérison sans séquelle. L'évolution s'est compliquée d'embolie pulmonaire dans 13,6% et de décès dans 4,5%. CONCLUSION: La thrombose veineuse profonde des membres occupe une place importante parmi les pathologies cardiovasculaires en milieu spécialisé cardiologique à Bamako et l'infection au VIH semble augmenter sa prévalence.

4.
Mali Med ; 30(1): 7-10, 2015.
Artigo em Francês | MEDLINE | ID: mdl-29927150

RESUMO

OBJECTIVE: This study aimed to describe epidemiological, clinical, and biological aspects of proteinuria in hypertensive patients in the cardiology department of the Gabriel Touré University Hospital in Bamako. PATIENTS AND METHODS: A cross-sectional descriptive study conducted from January to December 2007 in the cardiology department of the Gabriel Touré University Hospital. RESULTS: A total of 114 subjects were included (60 men and 54 women) with a mean age of 57 years, the sex ratio was 1.11. In the hypertensive population, stage 1 to 2 chronic renal failure was found in 12.9% (114/880). Patients under 60 years of age were more frequently affected with 61.5%. Proteinuria was found in 37 among 114 patients in chronic renal failure (32.5%). Proteinuria frequency in the general hypertensive population was 4.2% (37/880). Microalbuminuria was predominant compared to macro-albuminuria: 25.5% versus 7%. Dyspnea (38.6%) and headache (36.8%) were the main symptoms of hypertension. Renal ultrasound was abnormal in 14.1% with a predominance of stage 0 (76%), stages 1 and 2 each accounted for 7%. CONCLUSION: Proteinuria is a biological anomaly frequently associated with hypertension. His research is required when renal impairment is associated with hypertension. Its discovery in hypertension significantly changes the management strategy of this affection.


OBJECTIF: Ce travail visait à décrire les aspects épidémiologiques, cliniques et biologiques de la protéinurie chez l'hypertendu avec une augmentation de la créatininémie dans le service de cardiologie du CHU Gabriel TOURE de Bamako. PATIENTS ET MÉTHODES: L'étude était transversale et descriptive allant du 1er Janvier au 31 Décembre 2007 dans le service de cardiologie du CHU Gabriel TOURE. RÉSULTATS: Au total 114 sujets ont étés inclus, dont 60 hommes et 54 femmes, en moyenne âgés de 57 ans, le sex ratio était de 1,11. Dans la population d'hypertendus, l'IRC débutante à modérée avait une fréquence de 12,9% (114/880). Les patients âgés de moins de 60 ans étaient plus nombreux avec une fréquence de 61,5%. La protéinurie était retrouvée chez 37/114 patients en insuffisance rénale chronique soit 32,5%. La fréquence de la protéinurie dans la population générale d'hypertendus était de 4,2 % (37/880).L'atteinte rénale marquée par la micro-albuminurie était prédominante par rapport à la macro-albuminurie : 25,5% contre 7%. La dyspnée (38,6%) et les céphalées (36,8%) étaient les principales manifestations de l'HTA. L'échographie rénale était anormale dans 14,1% avec une prédominance du stade 0 (76 %), les stades 1 et 2 représentaient chacun 7%. CONCLUSION: La protéinurie est une anomalie biologique fréquemment associée à l'HTA. Sa recherche s'impose lorsqu'une atteinte rénale est associée à l'HTA. Sa découverte au cours de l'HTA change considérablement la stratégie de prise en charge de cette affection.

5.
Med Trop (Mars) ; 64(2): 151-4, 2004.
Artigo em Francês | MEDLINE | ID: mdl-15460143

RESUMO

Peripartum heart failure due to unexplained dilated cardiomyopathy is a common disorder as Savannak-Sahelian Africa. One of the many suspected risk factors identified is selenium deficiency. The purpose of this study was to measure plasma selenium levels in patients with peripartum heart failure due to cardiomyopathy in Bamako, Republic of Mali and compare data with healthy Sahalian women with the same obstetrical status. Plasma selenium was measured in a patient group consisting of 28 Malian women presenting peripartum heart failure and in a control group of 28 healthy breast-feeding Nigerien women of comparable age. The criteria for matching the two groups was parity (similar number of deliveries) since multiparity is a risk factor for peripartum cardiomyopathy. The Wilcoxon test (nonparametric) was used to compare the 2 groups considering up value < 0.05 as significant. Plasma selenium was significantly lower in patients from Mali than in controls from Niger (65 +/- 17 ng/ml vs. 78 +/- 17 ng/ml, p = 0.01). The results of this study showing lower plasma selenium in Bamako patients with peripartum cardiomyopathy than in a matching healthy control population confirms the previous data from the Niamey study.


Assuntos
Insuficiência Cardíaca/sangue , Complicações Cardiovasculares na Gravidez/sangue , Transtornos Puerperais/sangue , Selênio/sangue , Feminino , Humanos , Mali , Gravidez
6.
Mali Med ; 29(4): 34-37, 2014.
Artigo em Francês | MEDLINE | ID: mdl-30049113

RESUMO

AIM: To specify indications and main anomalies of the 24 hours electrocardiogram in Bamako. METHODOLOGY: The study was retrospective and conducted from 1st January 2008 to 31st July 2013, on patients whose file comprised a readable recording holter. The Holter recordings were analyzed by the software synetec (syneview 2) of ELA medical. Patients data were analyzed by SPSS 18 and redaction made using Word 2010. RESULTS: 90.2% of the recordings were retained. Mean Age of the sample was of 44,02 ± 16,95 years, the sex-ratio H: F 1,18 with 79.3% of patients coming from the services of cardiology. The indications were: palpitations (32.6%), suspicions of disorder of the rate/rhythm (27.2%), loss of consciousness, cerebral vascular accidents ischemic each one 15.2% and seeks of cause of faintness in (9.8%). An anomaly was found for the indications of disorder of the cardiac rhythm, palpitations, the cerebral vascular accidents ischemic, fainting and the losses of consciousness in resp. 80%, 66.6%, 28.5%, 22.2% and 14.2%. CONCLUSION: The 24 hours electrocardiographic recording is an examination of a great value in looking for cardiac rhythm disorders field of the disorders of the cardiac rhythm. Its provision will have to be effective in the university structures and the evolution towards the forms at longer duration quickly undertaken in Mali.


BUT: Préciser les indications et les principales anomalies du Holter électrocardiographique à Bamako. MÉTHODOLOGIE: L'étude était retrospective allant du 1er janvier 2008 au 31 juillet 2013 et portait sur des patients dont le dossier comportait un enregistrement holter bien lisible. Les enregistrements Holter étaient analysés par le logiciel synetec (syneview 2) de la société ELA médical. Les données des patients ont été analysées par SPSS 18 et saisies sur Word 2010. RÉSULTATS: 90,2% des examens holter effectués ont été retenus. L'âge moyen de l'échantillon était de 44,02 ± 16,95 ans, le sex-ratio H:F 1,18 avec 79,3% de patients provenant des services de cardiologie.Les indications étaient: palpitations ( 32,6%), suspicions de trouble du rythme (27,2 %), perte de connaissance, accidents vasculaires cérébraux ischémiques chacun 15,2% et recherche de cause de malaise dans (9,8%). Une anomalie était retrouvée pour les indications de trouble du rythme cardiaque, les palpitations, les accidents vasculaires cérébraux ischémiques, les malaises et les pertes de connaissance dans resp. 80%, 66,6, 28,5%, 22,2% et 14,2%. CONCLUSION: L'enregistrement Holter électrocardiographique de 24 heures est un examen d'une grande valeur dans le domaine des troubles du rythme cardiaque. Sa mise à disposition devra être effective dans les structures universitaires et l'évolution vers les formes à durée plus longue rapidement entreprise au Mali.

7.
Mali Med ; 29(1): 29-33, 2014.
Artigo em Francês | MEDLINE | ID: mdl-30049138

RESUMO

OBJECTIVE: This work aimed to study the quality of diagnosis and management of high blood pressure (HBP) by the practitioners of the Gabriel TOURÉ and point G teaching hospitals of Bamako. MATERIALS AND METHODS: It was a descriptive and analytical, cross-sectional study during the study period from 1st March 2009 to 28 February 2010. It included all physicians and paramedics of the teaching hospital of the Point G and Gabriel TOURÉ in Bamako. RESULTS: A total of 283 practitioners (physicians and the paramedics) from both teaching hospitals have accepted our questionnaire, including 133 doctors and 185 paramedics. CHU Gabriel TOURÉ accounted for 55.1%, the majority came from the department of cardiology with 18.4%. Doctors accounted for the largest square with 47.0%. The majority of our practitioners (59%) say it takes at least one session during three medical consultations to diagnose the HBP. Only 29,60% define the HBP from 140/90 mm Hg. With a blood pressure goal of 58, 30% and 57.20% of practitioners claimed to retain 140/90 mm Hg, respectively for the diabetic and the renal-insufficient patients. A considerable number of our practitioners (27.9%) still used in pregnant women the triplet diuretic/IEC/diet without salt. The information of patients on some important aspects of the pathology prior to any therapeutic strategy had been conducted in 63.6. CONCLUSION: The high blood pressure must be a major concern for medical and paramedical staff today.


OBJECTIF: Ce travail visait à étudier la qualité du diagnostic et de la prise en charge de l'hypertension artérielle par les praticiens du CHU Gabriel TOURE et de point G de Bamako. MATÉRIELS ET MÉTHODES: Il s'agissait d'une étude transversale descriptive et analytique, pendant la période d'étude du 1er mars 2009 au 28 Février 2010. Elle a concerné l'ensemble des médecins et des paramédicaux des centres hospitalo ­ universitaires du Point G et Gabriel TOURE de Bamako. RÉSULTATS: Au total 283 praticiens (médecins et des paramédicaux) des deux centres hospitalo - universitaires ont accepté notre questionnaire, dont 133 médecins et 185 paramédicaux. Le CHU Gabriel TOURE représentait 55,1%, la majorité provenait du service de cardiologie avec 18,4%. Les médecins ont constitué la plus grande proportion avec 47,0%. La majorité de nos praticiens (59%) affirmaient qu'il faut au moins une séance de prise tensionnelle pendant trois consultations médicales pour diagnostiquer l'HTA. Seulement 29,60% définissent l'HTA à partir de 140/90 mm Hg. Comme objectif tensionnel 58, 30% et 57,20% des praticiens affirmaient retenir 140/90 mm Hg respectivement chez le diabétique et l'insuffisant rénal. Un nombre considérable de nos praticiens (27,9 %) utilisait encore chez la femme enceinte le triplet Diurétique/IEC/Régime sans sel. L'information des patients sur certains aspects importants de la pathologie avant toute stratégie thérapeutique avait été effectuée dans 63,6. CONCLUSION: L'hypertension artérielle doit être une préoccupation majeure pour tout personnel médical et paramédical de nos jours.

8.
Mali Med ; 28(4): 50-56, 2013.
Artigo em Francês | MEDLINE | ID: mdl-30049155

RESUMO

OBJECTIVE: This work aimed to describe the epidemiological, clinical, biological and ultrasound aspects of the subclinical renal failure in hypertensive patients in the department of cardiology of the Gabriel TOURÉ University Hospital of Bamako. PATIENTS AND METHODS: The study was cross-sectional and prospective from 1 January 2007 to 31 December 2007 in the cardiology department of the Gabriel Touré University Hospital. These were all patients who achieved at least the basic test for renal impairment such as serum creatinine, 24h proteinuria, renal ultrasound. RESULTS: Total of 114 patients with kidney failure without evocative clinical symptoms have been included, among them 60 men and 54 women, average age of 57 years. In the hypertensive population, the beginner to moderate chronic renal failure had a frequency of 12.9% (114/880), the sex ratio was 1.11 in favor of men. Patients aged less than 60 years were more numerous with a frequency of 61.5%. Dyspnea (38.6%), and headache (36.8%) were the main manifestations of the high blood pressure (HBP). Renal disease characterized by microalbuminuria was predominant compared to the macro-albuminuria: 25.5% versus 7%. Renal ultrasound was abnormal in 14.1% with a predominance of stage 0 (86%), stages 1 and 2 were each 7%, we have not found any stage 3. CONCLUSION: Chronic renal failure is a frequent complication of the hypertension. Some biological tests are necessary for the diagnosis. Renal ultrasound remains a useful test for its assessment. The optimal treatment of high blood pressure is essential, as it not only reduces the overall cardiovascular risk of patients, but also slows or even stabilizes the worsening of renal function.


OBJECTIF: Ce travail visait à décrire les aspects épidémiologiques, cliniques, biologiques et échographiques de l'insuffisance rénale infraclinique chez l'hypertendu dans le service de cardiologie du CHU Gabriel TOURE de Bamako. PATIENTS ET MÉTHODES: L'étude était transversale et prospective allant du 1er Janvier 2007 au 31 Décembre 2007 dans le service de cardiologie du CHU Gabriel TOURE. Il s'agissait de l'ensemble des patients ayant au moins réalisé le bilan minimum d'atteinte rénale à savoir la créatininémie, la protéinurie de 24h, l'échographie rénale. RÉSULTATS: Au total 114 sujets présentant une insuffisance rénale sans manifestations cliniques évocatrices ont étés inclus, dont 60 hommes et 54 femmes, en moyenne âgés de 57 ans. Dans la population d'hypertendus, l'IRC débutante à modérée avait une fréquence de 12,9% (114/880), le sex ratio était de 1,11 en faveur des hommes. Les patients âgés de moins de 60 ans étaient plus nombreux avec une fréquence de 61,5%. La dyspnée (38,6%) et les céphalées (36,8%) étaient les principales manifestations de l'HTA. L'atteinte rénale marquée par la micro- albuminurie était prédominante par rapport à la macro- albuminurie: 25,5% contre 7%. L'échographie rénale était anormale dans 14,1% avec une prédominance du stade 0 (86%), les stades 1 et 2 représentaient chacun 7%, nous n'avons pas trouvé de stade 3. CONCLUSION: L'insuffisance rénale chronique reste une complication fréquente de l' HTA. Certains examens biologiques sont nécessaires pour le diagnostic. L'échographie rénale reste un examen utile pour son évaluation. Le traitement optimal de l'hypertension artérielle est essentiel car cela permet non seulement de diminuer le risque cardiovasculaire global des patients, mais aussi de ralentir la péjoration de la fonction rénale, ou même de la stabiliser.

9.
Mali Med ; 26(1): 3-6, 2011.
Artigo em Francês | MEDLINE | ID: mdl-22766101

RESUMO

Authors studied 30 cases of pulmonary emboli in BAMAKO in the departments of Cardiology at Point G hospital. The purpose of this work was to determine the pulmonary emboli's frequency, their signs and symptoms and to observe their outcome. Was eligible to study every patient hospitalised for pulmonary emboli confirmed by clinical signs and D- dimere test, with ECG and echocardiogram in most cases. The pulmonary emboli' frequency was 1,7%, with an average age of 51 years ± 16,9. Among causes the most frequent were hypertension (50%), phlebitis (40%), chronic cor pulmonale (30%), and heart failure (40%). Signs were respiratory distress (80%), haemoptysis (43%), syncope (20%), and circulatory collapse (15%). ECG show mostly right ventricular hypertrophy (93,3%) and x ray sometimes a characteristic aspect. Cardiac echography show essentially ventricular and auricular dilatation with a thrombus in 6,7% of the cases. The treatment was by heparin, AVK and analgesic. Mortality in study was 11, 3 %. So pulmonary embolus is always at high risk and sometimes it's diagnostic is difficult.


Assuntos
Embolia Pulmonar/epidemiologia , Embolia Pulmonar/etiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Ecocardiografia , Eletrocardiografia , Feminino , Produtos de Degradação da Fibrina e do Fibrinogênio/análise , Humanos , Masculino , Mali/epidemiologia , Pessoa de Meia-Idade , Estudos Prospectivos , Embolia Pulmonar/diagnóstico , Embolia Pulmonar/terapia , Estudos Retrospectivos
10.
Acta Trop ; 117(3): 202-6, 2011 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-21167118

RESUMO

BACKGROUND: Approximately, 15-20 of 40 HPVs that infect the female genital tract confer a high-risk of invasive cancer, thus HPVs account for 95% of cervix cancers. The objectives of this study were to: (i) estimate the prevalence of HPV infection in women infected with HIV in Ouagadougou, (ii) identify potential carcinogenic HPV strains and (iii) determine whether existing HPV vaccines match the isolated strains. METHODS: From May 2009 to April 2010, 250 HIV-infected women were included in this study. Each woman was screened for the presence of HPV and for HPV genotype using PCR/hybridization technique. RESULTS: Of the 250 HIV-infected women, 59.6% were infected with at least one type of HPV. High-risk HPVs were identified with the following prevalence: HPV-18 (25.0%); HPV-50'S (25.5%); HPV-30'S (20.8%); HPV-16 (4.7%); HPV-45 (3.7%). Low-risk HPVs were represented by HPV-6 (5.7%) and HPV-11 (0.9%). CONCLUSION: The issue of the study showed that the existing vaccines: Gardasil and Cervarix may be used in the country although they match only HPV-16, HPV-18, HPV-6 and HPV-11. Further investigations should be continued for the establishment of vaccine that matches all genotypes circulating in the country.


Assuntos
Impressões Digitais de DNA , Papillomaviridae/classificação , Papillomaviridae/genética , Infecções por Papillomavirus/genética , Adulto , Burkina Faso/epidemiologia , DNA Viral/análise , Feminino , Genoma Viral , HIV , Infecções por HIV/epidemiologia , Infecções por HIV/genética , Soropositividade para HIV/epidemiologia , Soropositividade para HIV/genética , Humanos , Papillomaviridae/isolamento & purificação , Infecções por Papillomavirus/complicações , Infecções por Papillomavirus/diagnóstico , Infecções por Papillomavirus/epidemiologia , Infecções por Papillomavirus/terapia , Infecções por Papillomavirus/virologia , Vacinas contra Papillomavirus/administração & dosagem , Vacinas contra Papillomavirus/genética , Vacinas contra Papillomavirus/uso terapêutico , Reação em Cadeia da Polimerase , Prevalência , Neoplasias do Colo do Útero/epidemiologia , Neoplasias do Colo do Útero/etiologia , Neoplasias do Colo do Útero/genética , Neoplasias do Colo do Útero/prevenção & controle
11.
J Gynecol Obstet Biol Reprod (Paris) ; 40(7): 633-8, 2011 Nov.
Artigo em Francês | MEDLINE | ID: mdl-21737213

RESUMO

OBJECTIVES: This work was carried out in order to determine the prevalence of different HPV genotypes in a population of women attending gynecological consultation. MATERIAL AND METHODS: From May to June 2010, cervical samples were obtained from 300 women attending gynecological consultation in two health centers in Ouagadougou. The strains of HPV genotyping was done using the technique of polymerase chain reaction (PCR) followed by reverse hybridization on nitrocellulose strips. RESULTS: Among the 73 women(24.3%) infected with HPV, only 27.4% (20/73) of them were infected with a HPV low risk (BR), the 72.6% (53/73). Other women were infected with at least one high risk HPV (HR). By combining the HPV genotypes found without taking into account the number of infected women, we found a total of 84 HPV among whom we have high-risk HPV : HPV-50'S(26/84 or 31.0%), HPV-18 (12/84 or 14.3%), HPV-16 (9/84 or 10.7%), HPV-30'S (5/84 or 5.9%), HPV-HR (5/84 or 5.9%) and HPV-45 (3/84 or 3.6%) and low-risk HPV: HPV-6 (15/84 or 17.9%) and HPV-BR (9/84 or 10.7%). We have found no HPV-11. DISCUSSION AND CONCLUSION: The prevalence of HPV found in our series is comparable to that found in the world. To complete this study, it would be necessary to investigate the prevalence of HPV found in cervical lesions in Burkina Faso.


Assuntos
Papillomaviridae/genética , Infecções por Papillomavirus/epidemiologia , Infecções por Papillomavirus/virologia , Adolescente , Adulto , Burkina Faso/epidemiologia , Colo do Útero/virologia , Feminino , Humanos , Incidência , Pessoa de Meia-Idade , Prevalência , Adulto Jovem
12.
Mali méd. (En ligne) ; 30(1): 3-6, 2015.
Artigo em Francês | AIM | ID: biblio-1265682

RESUMO

Objectif: Determiner la frequence des thromboses veineuses profondes des membres superieurs et inferieurs dans le milieu specialise cardiologique. Decrire les signes cliniques et para cliniques. Identifier les facteurs etiologiques. Evaluer l'evolution sous traitement. Materiel et methodes: Il s'agissait d'une etude prospective et longitudinale qui s'est deroulee du 1erjanvier 2007 au 31 mai 2008 dans le service de cardiologie du Centre Hospitalier Universitaire Gabriel Toure de Bamako. Etaient inclus tous les patients qui presentaient une thrombose veineuse profonde des membres confirmee echographiquement. Les donnees ont ete analysees avec le logiciel Epi info 6.04d. Resultats: 22 cas de thrombophlebite confirmee pour un total de 1171 hospitalisations; soit une frequence de 1;88 avec un age de survenue entre 30 et 44ans (40;9) sans aucune preference de sexe (sex ratio=1). Soixante et trois virgule six pour cent n'avaient aucun antecedent cardiovasculaire connu. Les signes cliniques etaient evocateurs dans 90;9. L'alitement prolonge etait present dans 59;09 des cas; associe a l'infection au VIH dans 18;1. L'atteinte du membre inferieur gauche predominait (72;7); un seul cas du membre superieur gauche (4;5). L'atteinte du reseau profond predominait (86;3) avec un siege preferentiellement proximal (72;7). La veine femorale a ete la plus thrombosee (50). Quatre-vingt et six virgule trois pour cent des patients ont recu les Heparines de Bas Poids Moleculaire (HBPM) + Anti Vitamine K (AVK) avec 68;18 de guerison sans sequelle. L'evolution s'est compliquee d'embolie pulmonaire dans 13;6 et de deces dans 4;5. Conclusion: La thrombose veineuse profonde des membres occupe une place importante parmi les pathologies cardiovasculaires en milieu specialise cardiologique a Bamako et l'infection au VIH semble augmenter sa prevalence


Assuntos
Serviço Hospitalar de Cardiologia , Extremidades , Embolia Pulmonar , Tromboflebite/epidemiologia
13.
Mali méd. (En ligne) ; 30(1): 7-10, 2015.
Artigo em Francês | AIM | ID: biblio-1265683

RESUMO

Objectif. Ce travail visait a decrire les aspects epidemiologiques; cliniques et biologiques de la proteinurie chez l'hypertendu avec une augmentation de la creatininemie dans le service de cardiologie du CHU Gabriel TOURE de Bamako. Patients et methodes. L'etude etait transversale et descriptive allant du 1er Janvier au 31 Decembre 2007 dans le service de cardiologie du CHU Gabriel TOURE. Resultats. Au total 114 sujets ont etes inclus; dont 60 hommes et 54 femmes; en moyenne ages de 57 ans; le sex ratio etait de 1;11. Dans la population d'hypertendus; l'IRC debutante a moderee avait une frequence de 12;9 (114/880). Les patients ages de moins de 60 ans etaient plus nombreux avec une frequence de 61;5. La proteinurie etait retrouvee chez 37/114 patients en insuffisance renale chronique soit 32;5. La frequence de la proteinurie dans la population generale d'hypertendus etait 4;2 (37/880).L'atteinte renale marquee par la micro albuminurie etait predominante par rapport a la macro albuminurie : 25;5 contre 7. La dyspnee (38;6) et les cephalees (36;8) etaient les principales manifestations de l'HTA. L'echographie renale etait anormale dans 14;1 avec une predominance du stade 0 (76); les stades 1 et 2 representaient chacun 7. Conclusion. La proteinurie est une anomalie biologique frequemment associee a l'HTA. Sa recherche s'impose lorsqu'une atteinte renale est associee a l'HTA. Sa decouverte au cours de l'HTA change considerablement la strategie de prise en charge de cette affection


Assuntos
Serviço Hospitalar de Cardiologia , Hipertensão , Proteinúria , Insuficiência Renal Crônica
14.
Pak J Biol Sci ; 13(19): 951-5, 2010 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-21313918

RESUMO

The vaginal swabs among HIV-positive women in Africa often revealed opportunistic infections such as human Papillomavirus (HPV) and Mycoplasma that induce respectively cervix cancer and diseases such as vaginosis, abortions, infertility in through salpingitis. The purposes of this study were to: (1) seek for, the prevalence of pathogens such as HPV and Mycoplasma; (2) characterize the strains of HPV and estimate their prevalence; (3) identify among these women, those who were co-infected by these pathogens in order to cure them. From February 2009 to January 2010, 156 HIV-positive women attending our medical centers and aged from 19-45 years (mean age 33.65 +/- 5.75 years) had voluntarily accepted vaginal specimen's tests. PCR, ELISA and molecular hybridization were used for the identification and characterization of these pathogens. The results revealed the presence of Mycoplasma and HPV in 25.64 and 58.33% cases, respectively. The following HPV genotypes and the following prevalence were recorded: HPV-50'S (24.11%), HPV-18 (21.28%), HPV-30'S (18.44%) and HPV-16 (5.67%). The study also enable the identification of co-infections such as HPV-18 strains with HPV-30'S (5.67%) and HPV-30'S with HPV-50'S (3.55%). Other germs infecting the female genital tract including Candida albicans (20.51%), Escherichia coli (12.18%), Treponema pallidum (3.85%), Streptococcus agalactiae (3.21%) and Staphylococcus aureus (1.92%) were isolated. This preliminary research work showed the incidence of several genital pathogens, this could be a springboard for nationwide epidemiological study on HPV strains circulating in Burkina Faso.


Assuntos
Alphapapillomavirus/isolamento & purificação , Infecções por HIV/complicações , Infecções por Papillomavirus/epidemiologia , Burkina Faso/epidemiologia , Feminino , Humanos , Infecções por Papillomavirus/complicações , Prevalência
15.
Mali Med ; 25(1): 57-60, 2010.
Artigo em Francês | MEDLINE | ID: mdl-21435996

RESUMO

AIM: The study aims to describe cardiovascular risk factor according to gender in hospital. MATERIAL AND METHODS: Il was a prospective study from april 2007 to march 2008 including 146 highblood pressure patients from 2 medical centre in Bamako. Gathering and analysis were performed with SPSS 11. RESULTS: 67% were female, the mean age reached 48,82. the BMI was significantly higher in female (P <0,001). Female were mainly registered between 30 and 44 years, and male between 45-59 years. Overweight and obesity were more represented in female and obesity in 30-44 years old patients. Isolated highblood pressure was found in 58,90%, 7,53% of patients had the 3 major cardiovascular risk factor CONCLUSION: Isolated highblood pressure was by far the most frequent. Although the cardiovascular risk rises with the others associations, they were rare and don't significantly differ in each gender. The tendency to overweight and obesity in female should be confirmed by others studies.


Assuntos
Doenças Cardiovasculares/epidemiologia , Fatores Sexuais , Adulto , Idoso , Índice de Massa Corporal , Comorbidade , Complicações do Diabetes/epidemiologia , Feminino , Maternidades/estatística & dados numéricos , Hospitais Universitários/estatística & dados numéricos , Humanos , Hiperlipidemias/epidemiologia , Hipertensão/epidemiologia , Masculino , Mali/epidemiologia , Pessoa de Meia-Idade , Sobrepeso/epidemiologia , Estudos Prospectivos , Fatores de Risco , Adulto Jovem
16.
Mali Med ; 24(1): 44-7, 2009.
Artigo em Francês | MEDLINE | ID: mdl-19666380

RESUMO

AIM: To study epidemiological aspects of the high blood pressure in pregnancy in Bamako. MATERIAL AND METHODS: The study was prospective from january to december 2006 about 250 pregnant with arterial hypertension and without any other cardiovascular disorder. The study was performed in CHU Gabriel Touré and CSRef I and V in Bamako using SPSS v. 11 for collecting and analyzing data. RESULTS: Arterial hypertension prevalence was 6,5%, with 38% between 20-29 years. 36,8% of them were primigravida 32,4% and 32,4% had 1-3 gestations. 85,6% were married, 74% housewives. 57,6% of the pregnant were not send to school and 28% had primary school instruction 16,4% took contraceptives and 6% were obese. 57,2% didn't have the required minimal number of 3 prenatal consultations and 76,8% were seen in the third trimenon. High blood pressure stage 1 was seen in 40% and stage 2 in 42,4%. Pre-eclampsia and chronic Hypertension made resp. 50,4% and 22%. CONCLUSION: High blood pressure in pregnancy is characterized by an later occur, by housewives with predominance of stage 1 and 3. Prenatal care is characterized by difficulties in realizing investigations and consultations in quantitative insuffisant prenatal consultations.


Assuntos
Hipertensão Induzida pela Gravidez/epidemiologia , Adulto , Feminino , Humanos , Mali/epidemiologia , Gravidez , Cuidado Pré-Natal/estatística & dados numéricos , Estudos Prospectivos , Adulto Jovem
17.
Mali Med ; 23(4): 60-2, 2008.
Artigo em Francês | MEDLINE | ID: mdl-19617176

RESUMO

AIM: The study aims to describe pericarditis in HIV-infected patients in epidemiological, clinical and paraclinical aspects. MATERIAL AND METHODS: In a prospective study from april 2005 to march 2006, 49 patients from 2 medical centers, were recruited grounded on clinic, echocardiographic evaluation et and the positivity of the HIV-serology. Data were collected and analysed using SPSS v.11. 3) RESULTS: Pericardial involvement occurred in 5.97%, the ratio Male:Female was 1.7 and the mean age 40.5 years (28.6% between 21-30 years). 14.3% didn't show any general sign. Explanatory findings were cardiomegaly (67.5%), pericardial effusion (55%) and micro-voltage (28.5%). 20.4% of our patients showed cardiac tamponade, 15 patients (31%) healed and death occurred in 37% (18 patients). CONCLUSION: Pericarditis is not rare, especially in HIV-infection and is essentially tuberculous. We neither found relation between serotype and manifestations nor between manifestations and clinical stage.


Assuntos
Infecções por HIV/epidemiologia , HIV-1 , HIV-2 , Pericardite/epidemiologia , Adulto , Cardiomegalia/diagnóstico por imagem , Cardiomegalia/epidemiologia , Comorbidade , Feminino , Hospitais Universitários/estatística & dados numéricos , Humanos , Masculino , Mali/epidemiologia , Pessoa de Meia-Idade , Pericardite/diagnóstico por imagem , Pericardite Tuberculosa/diagnóstico por imagem , Pericardite Tuberculosa/epidemiologia , Estudos Prospectivos , Radiografia , Viés de Seleção , Ultrassonografia , Adulto Jovem
18.
Mali Med ; 22(4): 36-9, 2007.
Artigo em Francês | MEDLINE | ID: mdl-19434980

RESUMO

The determination of risk factors a low to prevent or to delay the apparition of certain diseases. Our study put out in Cardiology A of Hôpital du Point G. gold to determine the main risk factors of ischemic heart diseases between 162 patients. It appears that all classical risk factors (HBP, Diabetes, obesity, tobacco use, sedentary, menopause, contraceptives, dyslipidemia) were found among patients. It appears particularly that avoidable risk factors such tobacco use among young men, sedentary and obesity play important role in the beginning. So it is possible to deploy an efficient prevention politic.


Assuntos
Isquemia Miocárdica/epidemiologia , Isquemia Miocárdica/etiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Alcoolismo/epidemiologia , Estudos de Coortes , Diabetes Mellitus/epidemiologia , Dislipidemias/epidemiologia , Feminino , Humanos , Masculino , Mali/epidemiologia , Pessoa de Meia-Idade , Obesidade/epidemiologia , Pós-Menopausa , Fatores de Risco , Tabagismo/epidemiologia
20.
Mali méd. (En ligne) ; 25(1): 57-60, 2010. ilus
Artigo em Francês | AIM | ID: biblio-1265622

RESUMO

Le but est de décrire les facteurs de risque cardiovasculaire selon le sexe en milieu hospitalier. Matériel et méthodes : L'étude prospective d'avril 2007 à mars 2008 a porté sur 146 patients hypertendus de 2 structures sanitaires à Bamako. La collecte et l'analyse des données ont été réalisées avec SPSS v.11 Résultats : 67% de l'échantillon était de sexe féminin, la moyenne d'âge de 48,82. L'IMC était significativement supérieur dans le sexe féminin ( p< 0,001 ) La répartition par tranche d'âge laissait reconnaître un pic à 30-44 ans dans le sexe féminin contre 45-59 ans dans le sexe masculin. Le surpoids et l'obésité étaient prédominants dans le sexe féminin et la tranche d'âge la plus représentée dans l'obésité est celle des 30-44 ans. L'HTA isolée était la plus fréquente avec 58,90%. 7,53% présentaient les 3 facteurs de risque majeurs. Conclusion : La présence de l'HTA isolée est de loin la plus fréquente. Les autres associations bien qu'augmentant le risque global sont rares et ne diffèrent pas fondamentalement selon le sexe. La tendance au surpoids et à l'obésité dans le sexe féminin mérite d'être confirmée par d'autres études


Assuntos
Pressão Arterial , Doenças Cardiovasculares , Hipercolesterolemia , Mali
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