Detalhe da pesquisa
1.
A Drug Discovery Approach to a Reveal Novel Antioxidant Natural Source: The Case of Chestnut Burr Biomass.
Int J Mol Sci
; 25(5)2024 Feb 21.
Artigo
Inglês
| MEDLINE | ID: mdl-38473765
2.
Machine learning application for patient stratification and phenotype/genotype investigation in a rare disease.
Brief Bioinform
; 22(5)2021 09 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33538294
3.
Pharmacological Chaperones and Protein Conformational Diseases: Approaches of Computational Structural Biology.
Int J Mol Sci
; 24(6)2023 Mar 18.
Artigo
Inglês
| MEDLINE | ID: mdl-36982893
4.
Homogentisic acid induces autophagy alterations leading to chondroptosis in human chondrocytes: Implications in Alkaptonuria.
Arch Biochem Biophys
; 717: 109137, 2022 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35090868
5.
Untargeted NMR Metabolomics Reveals Alternative Biomarkers and Pathways in Alkaptonuria.
Int J Mol Sci
; 23(24)2022 Dec 13.
Artigo
Inglês
| MEDLINE | ID: mdl-36555443
6.
Homogentisic acid induces cytoskeleton and extracellular matrix alteration in alkaptonuric cartilage.
J Cell Physiol
; 236(8): 6011-6024, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33469937
7.
Leveraging proteomics in orphan disease research: pitfalls and potential.
Expert Rev Proteomics
; 18(4): 315-327, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33861161
8.
Protein thiolation index in microvolumes of plasma.
Anal Biochem
; 618: 114125, 2021 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33524411
9.
Biochemical Characterization of Cassiopea andromeda (Forsskål, 1775), Another Red Sea Jellyfish in the Western Mediterranean Sea.
Mar Drugs
; 19(9)2021 Aug 31.
Artigo
Inglês
| MEDLINE | ID: mdl-34564160
10.
CD93 Signaling via Rho Proteins Drives Cytoskeletal Remodeling in Spreading Endothelial Cells.
Int J Mol Sci
; 22(22)2021 Nov 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34830297
11.
Towards a Precision Medicine Approach Based on Machine Learning for Tailoring Medical Treatment in Alkaptonuria.
Int J Mol Sci
; 22(3)2021 Jan 26.
Artigo
Inglês
| MEDLINE | ID: mdl-33530326
12.
Homogentisic acid affects human osteoblastic functionality by oxidative stress and alteration of the Wnt/ß-catenin signaling pathway.
J Cell Physiol
; 235(10): 6808-6816, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31989660
13.
Mechanisms involved in the unbalanced redox homeostasis in osteoblastic cellular model of Alkaptonuria.
Arch Biochem Biophys
; 690: 108416, 2020 09 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32502471
14.
Interactive alkaptonuria database: investigating clinical data to improve patient care in a rare disease.
FASEB J
; 33(11): 12696-12703, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31462106
15.
Homogentisic acid is not only eliminated by glomerular filtration and tubular secretion but also produced in the kidney in alkaptonuria.
J Inherit Metab Dis
; 43(4): 737-747, 2020 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31609457
16.
Tumor-Associated Macrophages in Osteosarcoma: From Mechanisms to Therapy.
Int J Mol Sci
; 21(15)2020 Jul 23.
Artigo
Inglês
| MEDLINE | ID: mdl-32717819
17.
Homogentisic acid induces morphological and mechanical aberration of ochronotic cartilage in alkaptonuria.
J Cell Physiol
; 234(5): 6696-6708, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30341892
18.
Membrane Skeletal Protein S-Glutathionylation in Human Red Blood Cells as Index of Oxidative Stress.
Chem Res Toxicol
; 32(6): 1096-1102, 2019 06 17.
Artigo
Inglês
| MEDLINE | ID: mdl-30945548
19.
The small GTPase Rab5c is a key regulator of trafficking of the CD93/Multimerin-2/ß1 integrin complex in endothelial cell adhesion and migration.
Cell Commun Signal
; 17(1): 55, 2019 05 28.
Artigo
Inglês
| MEDLINE | ID: mdl-31138217
20.
Inhibiting PNP for the therapy of hyperuricemia in Lesch-Nyhan disease: Preliminary in vitro studies with analogues of immucillin-G.
J Inherit Metab Dis
; 42(1): 178-185, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30740729