RESUMO
BACKGROUND: Silver nanoparticles are widely used in various fields such as industry, medicine, biotechnology, and agriculture. However, the inevitable release of these nanoparticles into the environment poses potential risks to ecosystems and may affect plant productivity. Coronatine is one of the newly identified compounds known for its beneficial influence on enhancing plant resilience against various stress factors. To evaluate the effectiveness of coronatine pretreatment in mitigating the stress induced by silver nanoparticles on cress plants, the present study was carried out. RESULTS: Our findings indicated a decrease in multiple growth parameters, proline content, chlorophyll a, chlorophyll b, total chlorophyll, and carotenoids in cress plants exposed to silver nanoparticle treatment. This decline could be attributed to the oxidative stress induced by the presence of silver nanoparticles in the plants. Conversely, when coronatine treatment was applied, it effectively mitigated the reduction in growth parameters and pigments induced by the silver nanoparticles. Furthermore, we observed an increase in silver content in both the roots and shoot portions, along with elevated levels of malondialdehyde (MDA) content, hydrogen peroxide (H2O2), anthocyanins, glutathione (GSH), and antioxidant enzyme activities in plants exposed to silver nanoparticles. Concurrently, there was a decrease in total phenolic compounds, ascorbate, anthocyanins, and proline content. Pre-treatment of cress seeds with coronatine resulted in increased levels of GSH, total phenolic compounds, and proline content while reducing the silver content in both the root and shoot parts of the plant. CONCLUSIONS: Coronatine pre-treatment appeared to enhance both enzymatic and non-enzymatic antioxidant activities, thereby alleviating oxidative stress and improving the response to stress induced by silver nanoparticles.
RESUMO
BACKGROUND: Injury is a leading cause of morbidity and mortality worldwide, and even more so in low and middle-income countries (LMICs). Iran is a LMIC and lacks information regarding injury for program and policy purposes. This study aimed to describe the incidence and patterns of injury in one province in South Eastern Iran. METHODS: A hospital-based, retrospective case review using a routinely collected registry in all Emergency Departments in Sistan and Baluchistan province, Iran for 12 months in 2007-2008. RESULTS: In total 18,155 injuries were recorded during the study period. The majority of injuries in South Eastern Iran were due to road traffic crashes. Individuals living in urban areas sustained more injuries compared to individuals from rural areas. Males typically experienced more injuries than females. Males were most likely to be injured in a street/alley or village whereas females were most likely to be injured in or around the home. In urban areas, road traffic related injuries were observed to affect older age groups more than younger age groups. Poisoning was most common in the youngest age group, 0 to 4 years. CONCLUSIONS: This study provides data on incidence and patterns of injury in South Eastern Iran. Knowledge of injury burden, such as this paper, is likely to help policy makers and planners with health service planning and injury prevention.