Pesquisa | Secretaria de Estado da Saúde

1.

Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS Mutations.

Niaki, Amirhossein Ghanbari; Sarkar, Jaya; Cai, Xinyi; Rhine, Kevin; Vidaurre, Velinda; Guy, Brian; Hurst, Miranda; Lee, Jong Chan; Koh, Hye Ran; Guo, Lin; Fare, Charlotte M; Shorter, James; Myong, Sua.

Mol Cell ; 77(1): 82-94.e4, 2020 01 02.

Artigo Inglês | MEDLINE | ID: mdl-31630970

2.

Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.

Alexander, Elizabeth J; Ghanbari Niaki, Amirhossein; Zhang, Tao; Sarkar, Jaya; Liu, Yang; Nirujogi, Raja Sekhar; Pandey, Akhilesh; Myong, Sua; Wang, Jiou.

Proc Natl Acad Sci U S A ; 115(49): E11485-E11494, 2018 12 04.

Artigo Inglês | MEDLINE | ID: mdl-30442662

3.

Dimerization of SLX4 contributes to functioning of the SLX4-nuclease complex.

Yin, Jinhu; Wan, Bingbing; Sarkar, Jaya; Horvath, Kent; Wu, Jian; Chen, Yong; Cheng, Guangjuan; Wan, Ke; Chin, Peiju; Lei, Ming; Liu, Yie.

Nucleic Acids Res ; 44(10): 4871-80, 2016 06 02.

Artigo Inglês | MEDLINE | ID: mdl-27131364

4.

SLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediates.

Sarkar, Jaya; Wan, Bingbing; Yin, Jinhu; Vallabhaneni, Haritha; Horvath, Kent; Kulikowicz, Tomasz; Bohr, Vilhelm A; Zhang, Yanbin; Lei, Ming; Liu, Yie.

Nucleic Acids Res ; 43(12): 5912-23, 2015 Jul 13.

Artigo Inglês | MEDLINE | ID: mdl-25990736

5.

Defective repair of uracil causes telomere defects in mouse hematopoietic cells.

Vallabhaneni, Haritha; Zhou, Fang; Maul, Robert W; Sarkar, Jaya; Yin, Jinhu; Lei, Ming; Harrington, Lea; Gearhart, Patricia J; Liu, Yie.

J Biol Chem ; 290(9): 5502-11, 2015 Feb 27.

Artigo Inglês | MEDLINE | ID: mdl-25572391

6.

Yeast mitochondrial leucyl-tRNA synthetase CP1 domain has functionally diverged to accommodate RNA splicing at expense of hydrolytic editing.

Sarkar, Jaya; Poruri, Kiranmai; Boniecki, Michal T; McTavish, Katherine K; Martinis, Susan A.

J Biol Chem ; 287(18): 14772-81, 2012 Apr 27.

Artigo Inglês | MEDLINE | ID: mdl-22383526

7.

Amino-acid-dependent shift in tRNA synthetase editing mechanisms.

Sarkar, Jaya; Martinis, Susan A.

J Am Chem Soc ; 133(46): 18510-3, 2011 Nov 23.

Artigo Inglês | MEDLINE | ID: mdl-22017352

8.

The microscopic origin of self-organized nanostripe pattern formation on an electropolished aluminium surface.

Sarkar, Jaya; Khan, Gobinda Gopal; Basumallick, A.

Nanotechnology ; 20(9): 095604, 2009 Mar 04.

Artigo Inglês | MEDLINE | ID: mdl-19417495

9.

Single-Molecule and Ensemble Methods to Probe Initial Stages of RNP Granule Assembly.

Sarkar, Jaya; Myong, Sua.

Methods Mol Biol ; 1814: 325-338, 2018.

Artigo Inglês | MEDLINE | ID: mdl-29956241

10.

Fanconi anemia proteins in telomere maintenance.

Sarkar, Jaya; Liu, Yie.

DNA Repair (Amst) ; 43: 107-12, 2016 07.

Artigo Inglês | MEDLINE | ID: mdl-27118469

11.

SLX4 assembles a telomere maintenance toolkit by bridging multiple endonucleases with telomeres.

Wan, Bingbing; Yin, Jinhu; Horvath, Kent; Sarkar, Jaya; Chen, Yong; Wu, Jian; Wan, Ke; Lu, Jian; Gu, Peili; Yu, Eun Young; Lue, Neal F; Chang, Sandy; Liu, Yie; Lei, Ming.

Cell Rep ; 4(5): 861-9, 2013 Sep 12.

Artigo Inglês | MEDLINE | ID: mdl-24012755

12.

The origin of oxidized guanine resolves the puzzle of oxidation-induced telomere-length alterations.

Sarkar, Jaya; Liu, Yie.

Nat Struct Mol Biol ; 23(12): 1070-1071, 2016 12 06.

Artigo Inglês | MEDLINE | ID: mdl-27922610

13.

Characterization of benzoxaborole-based antifungal resistance mutations demonstrates that editing depends on electrostatic stabilization of the leucyl-tRNA synthetase editing cap.

Sarkar, Jaya; Mao, Weimin; Lincecum, Tommie L; Alley, M R K; Martinis, Susan A.

FEBS Lett ; 585(19): 2986-91, 2011 Oct 03.

Artigo Inglês | MEDLINE | ID: mdl-21856301

14.

La estrategia de los niños sanos: experiencias de la implementación de AIEPI comunitario en Bolivia / Es

Sarkar, Jaya.

La Paz; PLAN; ene. 2005. 78 p. ilus, tab.

Monografia Espanhol | LIBOCS, LIBOSP | ID: biblio-1304850

15.

La estrategia de los niños sanos: experiencias de la implementación de AIEPI comunitario en Bolivia / Es

Sarkar, Jaya.

La Paz; PLAN; ene. 2005. 78 p. ilus, tab.

Monografia Espanhol | LIBOCS, LIBOE | ID: biblio-1294959

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Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS Mutations.

Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.

Dimerization of SLX4 contributes to functioning of the SLX4-nuclease complex.

SLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediates.

Defective repair of uracil causes telomere defects in mouse hematopoietic cells.

Yeast mitochondrial leucyl-tRNA synthetase CP1 domain has functionally diverged to accommodate RNA splicing at expense of hydrolytic editing.

Amino-acid-dependent shift in tRNA synthetase editing mechanisms.

The microscopic origin of self-organized nanostripe pattern formation on an electropolished aluminium surface.

Single-Molecule and Ensemble Methods to Probe Initial Stages of RNP Granule Assembly.

Fanconi anemia proteins in telomere maintenance.

SLX4 assembles a telomere maintenance toolkit by bridging multiple endonucleases with telomeres.

The origin of oxidized guanine resolves the puzzle of oxidation-induced telomere-length alterations.

Characterization of benzoxaborole-based antifungal resistance mutations demonstrates that editing depends on electrostatic stabilization of the leucyl-tRNA synthetase editing cap.

La estrategia de los niños sanos: experiencias de la implementación de AIEPI comunitario en Bolivia / Es

La estrategia de los niños sanos: experiencias de la implementación de AIEPI comunitario en Bolivia / Es