Detalhe da pesquisa
1.
Somatostatin-evoked Aß catabolism in the brain: Mechanistic involvement of α-endosulfine-KATP channel pathway.
Mol Psychiatry
; 27(3): 1816-1828, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34737456
2.
A third-generation mouse model of Alzheimer's disease shows early and increased cored plaque pathology composed of wild-type human amyloid ß peptide.
J Biol Chem
; 297(3): 101004, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34329683
3.
APP mouse models for Alzheimer's disease preclinical studies.
EMBO J
; 36(17): 2473-2487, 2017 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28768718
4.
Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation.
J Biol Chem
; 294(34): 12754-12765, 2019 08 23.
Artigo
Inglês
| MEDLINE | ID: mdl-31273083
5.
Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency.
Hum Mol Genet
; 23(6): 1467-78, 2014 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24163244
6.
The dual functions of the extreme N-terminus of TDP-43 in regulating its biological activity and inclusion formation.
Hum Mol Genet
; 22(15): 3112-22, 2013 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23575225
7.
Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress.
Acta Neuropathol
; 128(4): 505-24, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-25173361
8.
Non-human primate model of amyotrophic lateral sclerosis with cytoplasmic mislocalization of TDP-43.
Brain
; 135(Pt 3): 833-46, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-22252998
9.
Use of the Representative Base Editing Tool Target-AID to Introduce Pathogenic Mutations into Mice.
Methods Mol Biol
; 2606: 87-97, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36592310
10.
Introduction of Genetic Mutations Into Mice by Base Editor and Target-AID.
Methods Mol Biol
; 2637: 111-124, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36773142
11.
A fully automated home cage for long-term continuous phenotyping of mouse cognition and behavior.
Cell Rep Methods
; 3(7): 100532, 2023 07 24.
Artigo
Inglês
| MEDLINE | ID: mdl-37533650
12.
Neuronal glutathione loss leads to neurodegeneration involving gasdermin activation.
Sci Rep
; 13(1): 1109, 2023 01 20.
Artigo
Inglês
| MEDLINE | ID: mdl-36670138
13.
Cystatin F (Cst7) drives sex-dependent changes in microglia in an amyloid-driven model of Alzheimer's disease.
Elife
; 122023 12 12.
Artigo
Inglês
| MEDLINE | ID: mdl-38085657
14.
A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury.
Sci Transl Med
; 15(713): eabo6889, 2023 09 13.
Artigo
Inglês
| MEDLINE | ID: mdl-37703352
15.
Assessments of prolonged effects of desflurane and sevoflurane on motor learning deficits in aged AppNL-G-F/NL-G-F mice.
Mol Brain
; 15(1): 32, 2022 04 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35387663
16.
An isogenic panel of App knock-in mouse models: Profiling ß-secretase inhibition and endosomal abnormalities.
Sci Adv
; 8(23): eabm6155, 2022 06 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35675411
17.
Recent Advances in the Modeling of Alzheimer's Disease.
Front Neurosci
; 16: 807473, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35431779
18.
Increased CSF-decorin predicts brain pathological changes driven by Alzheimer's Aß amyloidosis.
Acta Neuropathol Commun
; 10(1): 96, 2022 07 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35787306
19.
Multimodal analyses of a non-human primate model harboring mutant amyloid precursor protein transgenes driven by the human EF1α promoter.
Neurosci Res
; 185: 49-61, 2022 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-36075457
20.
Early Identification of Alzheimer's Disease in Mouse Models: Application of Deep Neural Network Algorithm to Cognitive Behavioral Parameters.
iScience
; 24(3): 102198, 2021 Mar 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33733064