Detalhe da pesquisa
1.
PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation.
Mol Cell
; 82(22): 4353-4367.e6, 2022 11 17.
Artigo
Inglês
| MEDLINE | ID: mdl-36272411
2.
Creating memories: molecular mechanisms of CRISPR adaptation.
Trends Biochem Sci
; 47(6): 464-476, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35236570
3.
CRISPR-Cas effector specificity and cleavage site determine phage escape outcomes.
PLoS Biol
; 21(4): e3002065, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37058530
4.
Cas4-Dependent Prespacer Processing Ensures High-Fidelity Programming of CRISPR Arrays.
Mol Cell
; 70(1): 48-59.e5, 2018 04 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29602742
5.
CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes.
Nucleic Acids Res
; 52(D1): D590-D596, 2024 Jan 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37889041
6.
Prokaryotic Argonaute Uses an All-in-One Mechanism to Provide Host Defense.
Mol Cell
; 65(6): 957-958, 2017 Mar 16.
Artigo
Inglês
| MEDLINE | ID: mdl-28306508
7.
The Revolution Continues: Newly Discovered Systems Expand the CRISPR-Cas Toolkit.
Mol Cell
; 68(1): 15-25, 2017 Oct 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28985502
8.
Cas4/1 dual nuclease activities enable prespacer maturation and directional integration in a type I-G CRISPR-Cas system.
J Biol Chem
; 299(9): 105178, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37607619
9.
Conformational Control of Cascade Interference and Priming Activities in CRISPR Immunity.
Mol Cell
; 64(4): 826-834, 2016 11 17.
Artigo
Inglês
| MEDLINE | ID: mdl-27871367
10.
Systematic in vitro specificity profiling reveals nicking defects in natural and engineered CRISPR-Cas9 variants.
Nucleic Acids Res
; 49(7): 4037-4053, 2021 04 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33744974
11.
CRISPR-Cas12a has widespread off-target and dsDNA-nicking effects.
J Biol Chem
; 295(17): 5538-5553, 2020 04 24.
Artigo
Inglês
| MEDLINE | ID: mdl-32161115
12.
Mechanism of foreign DNA selection in a bacterial adaptive immune system.
Mol Cell
; 46(5): 606-15, 2012 Jun 08.
Artigo
Inglês
| MEDLINE | ID: mdl-22521690
13.
CRISPR interference and priming varies with individual spacer sequences.
Nucleic Acids Res
; 43(22): 10831-47, 2015 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26586800
14.
Structure of the yeast U2/U6 snRNA complex.
RNA
; 18(4): 673-83, 2012 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-22328579
15.
CRISPR-Cas12a exhibits metal-dependent specificity switching.
bioRxiv
; 2024 Jan 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38076861
16.
Cas4/1 dual nuclease activities enable prespacer maturation and directional integration in a type I-G CRISPR-Cas system.
bioRxiv
; 2023 Jun 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37333257
17.
A tool for more specific DNA integration.
Science
; 382(6672): 768-769, 2023 11 17.
Artigo
Inglês
| MEDLINE | ID: mdl-37972178
18.
Miniature CRISPR-Cas12 endonucleases - Programmed DNA targeting in a smaller package.
Curr Opin Struct Biol
; 77: 102466, 2022 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-36170778
20.
U2-U6 RNA folding reveals a group II intron-like domain and a four-helix junction.
Nat Struct Mol Biol
; 11(12): 1237-42, 2004 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-15543154