Detalhe da pesquisa
1.
Assessment of AI-Based Protein Structure Prediction for the NLRP3 Target.
Molecules
; 27(18)2022 Sep 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36144532
2.
Triaging of DNA-Encoded Library Selection Results by High-Throughput Resynthesis of DNA-Conjugate and Affinity Selection Mass Spectrometry.
Bioconjug Chem
; 32(5): 1001-1007, 2021 05 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33914520
3.
Selections and screenings of DNA-encoded chemical libraries against enzyme and cellular targets.
Bioorg Med Chem Lett
; 39: 127851, 2021 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33631371
4.
Palladium-mediated Suzuki-Miyaura Cross-Coupling Reaction of Potassium Boc-protected aminomethyltrifluoroborate with DNA-Conjugated aryl bromides for DNA-Encoded chemical library synthesis.
Biochem Biophys Res Commun
; 533(2): 209-214, 2020 12 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32376009
5.
DNA-Compatible Copper-Catalyzed Oxidative Amidation of Aldehydes with Non-Nucleophilic Arylamines.
Bioconjug Chem
; 31(9): 2092-2097, 2020 09 16.
Artigo
Inglês
| MEDLINE | ID: mdl-32804494
6.
DNA-Compatible Cyclization Reaction to Access 1,3,4-Oxadiazoles and 1,2,4-Triazoles.
Org Lett
; 26(7): 1353-1357, 2024 Feb 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38335275
7.
DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2-p53 Inhibitor.
ACS Med Chem Lett
; 14(6): 820-826, 2023 Jun 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37312849
8.
Analysis of DNA-Encoded Library Screening Data: Selection of Molecules for Synthesis.
Methods Mol Biol
; 2541: 195-205, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36083558
9.
Discovery of SARS-CoV-2 main protease covalent inhibitors from a DNA-encoded library selection.
SLAS Discov
; 27(2): 79-85, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35063690
10.
Design, synthesis and selection of DNA-encoded small-molecule libraries.
Nat Chem Biol
; 5(9): 647-54, 2009 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-19648931
11.
DNA-Compatible Click Reaction Employing In Situ Generated Azides from Boronic Acids.
Curr Protoc
; 1(5): e125, 2021 May.
Artigo
Inglês
| MEDLINE | ID: mdl-33956399
12.
Discovery of a Highly Selective BET BD2 Inhibitor from a DNA-Encoded Library Technology Screening Hit.
J Med Chem
; 64(15): 10806-10833, 2021 08 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34251219
13.
Exploration of amino alcohol derivatives as novel, potent, and highly selective sphingosine-1-phosphate receptor subtype-1 agonists.
Bioorg Med Chem Lett
; 20(8): 2520-4, 2010 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20304639
14.
Off-DNA DNA-Encoded Library Affinity Screening.
ACS Comb Sci
; 22(1): 25-34, 2020 01 13.
Artigo
Inglês
| MEDLINE | ID: mdl-31829554
15.
Synthesis of 1,2-Amino Alcohols by Photoredox-Mediated Decarboxylative Coupling of α-Amino Acids and DNA-Conjugated Carbonyls.
Org Lett
; 22(24): 9484-9489, 2020 12 18.
Artigo
Inglês
| MEDLINE | ID: mdl-33170713
16.
Copper-Mediated DNA-Compatible One-Pot Click Reactions of Alkynes with Aryl Borates and TMS-N3.
Org Lett
; 22(11): 4146-4150, 2020 06 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32383596
17.
Solution-Phase DNA-Compatible Pictet-Spengler Reaction Aided by Machine Learning Building Block Filtering.
iScience
; 23(6): 101142, 2020 Jun 26.
Artigo
Inglês
| MEDLINE | ID: mdl-32446221
18.
Synthesis and evaluation of arylalkoxy- and biarylalkoxy-phenylamide and phenylimidazoles as potent and selective sphingosine-1-phosphate receptor subtype-1 agonists.
Bioorg Med Chem Lett
; 19(8): 2315-9, 2009 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19282175
19.
High-Throughput Solid-Phase Building Block Synthesis for DNA-Encoded Libraries.
Org Lett
; 21(23): 9353-9357, 2019 12 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31747291
20.
Development of DNA-Compatible Van Leusen Three-Component Imidazole Synthesis.
Org Lett
; 21(22): 9001-9004, 2019 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31664846