Detalhe da pesquisa
1.
Loss of hypothalamic MCH decreases food intake in amyotrophic lateral sclerosis.
Acta Neuropathol
; 145(6): 773-791, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37058170
2.
Absence of Subcerebral Projection Neurons Is Beneficial in a Mouse Model of Amyotrophic Lateral Sclerosis.
Ann Neurol
; 88(4): 688-702, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32588450
3.
Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.
EMBO J
; 35(10): 1077-97, 2016 05 17.
Artigo
Inglês
| MEDLINE | ID: mdl-26951610
4.
The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function.
FASEB J
; 32(11): 6159-6173, 2018 11.
Artigo
Inglês
| MEDLINE | ID: mdl-29879376
5.
Degeneration of serotonin neurons triggers spasticity in amyotrophic lateral sclerosis.
Ann Neurol
; 82(3): 444-456, 2017 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-28856708
6.
Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis.
Acta Neuropathol
; 133(6): 887-906, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28243725
7.
Alterations in the hypothalamic melanocortin pathway in amyotrophic lateral sclerosis.
Brain
; 139(Pt 4): 1106-22, 2016 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-26984187
8.
Serotonin 2B receptor slows disease progression and prevents degeneration of spinal cord mononuclear phagocytes in amyotrophic lateral sclerosis.
Acta Neuropathol
; 131(3): 465-80, 2016 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-26744351
9.
VAPB/ALS8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis elegans.
PLoS Genet
; 9(9): e1003738, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24039594
10.
Cortical hyperexcitability in mouse models and patients with amyotrophic lateral sclerosis is linked to noradrenaline deficiency.
Sci Transl Med
; 16(738): eadg3665, 2024 Mar 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38478631
11.
Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the Sod1 Mouse Model of Amyotrophic Lateral Sclerosis.
Brain Sci
; 11(3)2021 Mar 13.
Artigo
Inglês
| MEDLINE | ID: mdl-33805792
12.
Evidence that corticofugal propagation of ALS pathology is not mediated by prion-like mechanism.
Prog Neurobiol
; 200: 101972, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33309802
13.
Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects.
Nat Commun
; 12(1): 3028, 2021 05 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34021132
14.
Cortical Circuit Dysfunction as a Potential Driver of Amyotrophic Lateral Sclerosis.
Front Neurosci
; 14: 363, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-32410944
15.
FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis.
Nat Neurosci
; 22(11): 1793-1805, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31591561