Detalhe da pesquisa
1.
A Proteomic Study on the Membrane Protein Fraction of T Cells Confirms High Substrate Selectivity for the ER Translocation Inhibitor Cyclotriazadisulfonamide.
Mol Cell Proteomics
; 20: 100144, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34481949
2.
Non-HLA antibodies targeting angiotensin II Type 1 receptor and endothelin-1 Type A receptors induce endothelial injury via ß2-arrestin link to mTOR pathway.
Kidney Int
; 101(3): 498-509, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34757123
3.
Inhibitors of the Sec61 Complex and Novel High Throughput Screening Strategies to Target the Protein Translocation Pathway.
Int J Mol Sci
; 22(21)2021 Nov 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34769437
4.
Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain.
Mol Pharmacol
; 96(4): 452-462, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31399504
5.
Evidence of G-protein-coupled receptor and substrate transporter heteromerization at a single molecule level.
Cell Mol Life Sci
; 75(12): 2227-2239, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29290039
6.
A new variant in signal peptide of the human luteinizing hormone receptor (LHCGR) affects receptor biogenesis causing leydig cell hypoplasia.
Hum Mol Genet
; 24(21): 6003-12, 2015 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26246498
7.
Targeting Gâ Protein-Coupled Receptors by Capture Compound Mass Spectrometry: A Case Study with Sertindole.
Chembiochem
; 18(16): 1639-1649, 2017 08 17.
Artigo
Inglês
| MEDLINE | ID: mdl-28557180
8.
The specific monomer/dimer equilibrium of the corticotropin-releasing factor receptor type 1 is established in the endoplasmic reticulum.
J Biol Chem
; 289(35): 24250-62, 2014 Aug 29.
Artigo
Inglês
| MEDLINE | ID: mdl-24966326
9.
The Pseudo signal peptide of the corticotropin-releasing factor receptor type 2A prevents receptor oligomerization.
J Biol Chem
; 287(32): 27265-74, 2012 Aug 03.
Artigo
Inglês
| MEDLINE | ID: mdl-22689579
10.
Molecular sampling of the allosteric binding pocket of the TSH receptor provides discriminative pharmacophores for antagonist and agonists.
Biochem Soc Trans
; 41(1): 213-7, 2013 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23356285
11.
The proteoglycan syndecan 4 regulates transient receptor potential canonical 6 channels via RhoA/Rho-associated protein kinase signaling.
Arterioscler Thromb Vasc Biol
; 32(2): 378-85, 2012 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-22155451
12.
Inhibition of biosynthesis of human endothelin B receptor by the cyclodepsipeptide cotransin.
J Biol Chem
; 286(41): 35588-35600, 2011 Oct 14.
Artigo
Inglês
| MEDLINE | ID: mdl-21808059
13.
From molecular details of the interplay between transmembrane helices of the thyrotropin receptor to general aspects of signal transduction in family a G-protein-coupled receptors (GPCRs).
J Biol Chem
; 286(29): 25859-71, 2011 Jul 22.
Artigo
Inglês
| MEDLINE | ID: mdl-21586576
14.
Mutations that silence constitutive signaling activity in the allosteric ligand-binding site of the thyrotropin receptor.
Cell Mol Life Sci
; 68(1): 159-67, 2011 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-20652618
15.
Use of Kaede fusions to visualize recycling of G protein-coupled receptors.
Traffic
; 10(1): 2-15, 2009 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-18939954
16.
The pseudo signal peptide of the corticotropin-releasing factor receptor type 2a decreases receptor expression and prevents Gi-mediated inhibition of adenylyl cyclase activity.
J Biol Chem
; 285(43): 32878-32887, 2010 Oct 22.
Artigo
Inglês
| MEDLINE | ID: mdl-20682782
17.
Signaling-sensitive amino acids surround the allosteric ligand binding site of the thyrotropin receptor.
FASEB J
; 24(7): 2347-54, 2010 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-20179143
18.
Modulating TSH Receptor Signaling for Therapeutic Benefit.
Eur Thyroid J
; 9(Suppl 1): 66-77, 2020 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-33511087
19.
The sequence after the signal peptide of the G protein-coupled endothelin B receptor is required for efficient translocon gating at the endoplasmic reticulum membrane.
Mol Pharmacol
; 75(4): 801-11, 2009 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19136571
20.
A New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves' Orbitopathy.
Thyroid
; 29(1): 111-123, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30351237