RESUMO
Simultaneous uveal and orbital spread of breast carcinoma occurred in a male patient. We believe that this case is unusual because of the rarity of ocular metastases from carcinoma of the breast in men and the extremely long interval (ten years) between detection of the primary tumor and appearance of metastatic disease.
Assuntos
Neoplasias da Mama/patologia , Carcinoma Intraductal não Infiltrante/secundário , Neoplasias Orbitárias/secundário , Neoplasias Uveais/secundário , Carcinoma Intraductal não Infiltrante/patologia , Neoplasias da Coroide/patologia , Neoplasias da Coroide/secundário , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Orbitárias/patologia , Neoplasias Uveais/patologiaRESUMO
The pupil cycle time (PCT) was prolonged in 11 subjects with familial dysautonomia. In the younger age group (10-19 years), mean PCT was 872 +/- 88 msec as compared to 15 normal age matched controls (728 +/- 88). In the 3 oldest patients (30-39 years) mean PCT was 980 +/- 133 msec as compared to 13 age matched normals (748 +/- 56). It is proposed that prolongation of PCT in familial dysautonomia may be due to functional denervation of the iris or that it is a result of a structural abnormality of its musculature and/or its neuromuscular junctions.