Detalhe da pesquisa
1.
TDP-43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons.
EMBO J
; 35(21): 2350-2370, 2016 11 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27621269
2.
Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD.
Hum Mol Genet
; 26(4): 790-800, 2017 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28040728
3.
Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss.
Acta Neuropathol
; 134(2): 241-254, 2017 08.
Artigo
Inglês
| MEDLINE | ID: mdl-28409281
4.
Erratum to: Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing.
Acta Neuropathol
; 130(4): 557-8, 2015 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-26290407
5.
Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing.
Acta Neuropathol
; 130(4): 537-55, 2015 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-26085200
6.
C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration.
Acta Neuropathol
; 128(4): 485-503, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-25120191
7.
RNA versus protein toxicity in C9orf72 ALS/FTLD.
Acta Neuropathol
; 135(3): 475-479, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29450647
8.
Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins.
Acta Neuropathol
; 126(6): 881-93, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24132570
9.
A novel CHCHD10 mutation implicates a Mia40-dependent mitochondrial import deficit in ALS.
EMBO Mol Med
; 10(6)2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29789341
10.
Poly-GP in cerebrospinal fluid links C9orf72-associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD.
EMBO Mol Med
; 9(7): 859-868, 2017 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28408402
11.
Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins.
EMBO Mol Med
; 9(5): 687-702, 2017 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28351931
12.
Targeting RNA G-quadruplexes as new treatment strategy for C9orf72 ALS/FTD.
EMBO Mol Med
; 10(1): 4-6, 2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29175945