Detalhe da pesquisa
1.
Engineering a therapeutic lectin by uncoupling mitogenicity from antiviral activity.
Cell
; 163(3): 746-58, 2015 Oct 22.
Artigo
Inglês
| MEDLINE | ID: mdl-26496612
2.
A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate.
Nature
; 590(7845): 320-325, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33260195
3.
Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine.
Proc Natl Acad Sci U S A
; 119(30): e2203660119, 2022 07 26.
Artigo
Inglês
| MEDLINE | ID: mdl-35858448
4.
Development of a cellular model to study CCR8 signaling in tumor-infiltrating regulatory T cells.
Cancer Immunol Immunother
; 73(1): 11, 2024 Jan 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38231448
5.
Systematic assessment of chemokine ligand bias at the human chemokine receptor CXCR2 indicates G protein bias over ß-arrestin recruitment and receptor internalization.
Cell Commun Signal
; 22(1): 43, 2024 01 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38233929
6.
Natural carboxyterminal truncation of human CXCL10 attenuates glycosaminoglycan binding, CXCR3A signaling and lymphocyte chemotaxis, while retaining angiostatic activity.
Cell Commun Signal
; 22(1): 94, 2024 02 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38308278
7.
Selective synthesis of an elusive C-functional bis-cyclam and study of its inhibition of the CXCR4 chemokine receptor.
Org Biomol Chem
; 22(15): 3059-3067, 2024 04 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38545887
8.
Identification of novel human CC chemokine receptor 8 (CCR8) antagonists via the synthesis of naphthalene amide and sulfonamide isosteres.
Bioorg Chem
; 145: 107181, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38354503
9.
Synthesis of a 3,7-Disubstituted Isothiazolo[4,3-b]pyridine as a Potential Inhibitor of Cyclin G-Associated Kinase.
Molecules
; 29(5)2024 Feb 22.
Artigo
Inglês
| MEDLINE | ID: mdl-38474466
10.
Skeleton binding protein-1-mediated parasite sequestration inhibits spontaneous resolution of malaria-associated acute respiratory distress syndrome.
PLoS Pathog
; 17(11): e1010114, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34843584
11.
Synthesis and structure-activity relationship study of phenoxybenzylpiperazine analogues as CCR8 agonists.
Bioorg Chem
; 139: 106755, 2023 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37544272
12.
Stimulation of the atypical chemokine receptor 3 (ACKR3) by a small-molecule agonist attenuates fibrosis in a preclinical liver but not lung injury model.
Cell Mol Life Sci
; 79(6): 293, 2022 May 13.
Artigo
Inglês
| MEDLINE | ID: mdl-35562519
13.
A Proteomic Study on the Membrane Protein Fraction of T Cells Confirms High Substrate Selectivity for the ER Translocation Inhibitor Cyclotriazadisulfonamide.
Mol Cell Proteomics
; 20: 100144, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34481949
14.
Lung Microenvironments and Disease Progression in Fibrotic Hypersensitivity Pneumonitis.
Am J Respir Crit Care Med
; 205(1): 60-74, 2022 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34724391
15.
Insertion of an Amphipathic Linker in a Tetrapodal Tryptophan Derivative Leads to a Novel and Highly Potent Entry Inhibitor of Enterovirus A71 Clinical Isolates.
Int J Mol Sci
; 24(4)2023 Feb 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36834952
16.
Exploration of Pyrido[3,4-d]pyrimidines as Antagonists of the Human Chemokine Receptor CXCR2.
Molecules
; 28(5)2023 Feb 23.
Artigo
Inglês
| MEDLINE | ID: mdl-36903345
17.
Synthesis and Biological Evaluation of 2-Substituted Quinazolin-4(3H)-Ones with Antiproliferative Activities.
Molecules
; 28(23)2023 Dec 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38067641
18.
Preprotein signature for full susceptibility to the co-translational translocation inhibitor cyclotriazadisulfonamide.
Traffic
; 21(2): 250-264, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31675144
19.
Systemic cytokines and GlycA discriminate disease status and predict corticosteroid response in HTLV-1-associated neuroinflammation.
J Neuroinflammation
; 19(1): 293, 2022 Dec 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36482436
20.
Itaconic acid hybrids as potential anticancer agents.
Mol Divers
; 26(1): 1-14, 2022 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-33043404