Detalhe da pesquisa
1.
Hyperactive Ras in developmental disorders and cancer.
Nat Rev Cancer
; 7(4): 295-308, 2007 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-17384584
2.
Germline KRAS mutations cause Noonan syndrome.
Nat Genet
; 38(3): 331-6, 2006 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-16474405
3.
Suppression of leukemia development caused by PTEN loss.
Proc Natl Acad Sci U S A
; 108(4): 1409-14, 2011 Jan 25.
Artigo
Inglês
| MEDLINE | ID: mdl-21212363
4.
IL-15/IL-15Rα-Fc fusion protein XmAb24306 potentiates activity of CD3 bispecific antibodies through enhancing T cell expansion.
Mol Cancer Ther
; 2024 May 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38739434
5.
Translational PK/PD and the first-in-human dose selection of a PD1/IL15: an engineered recombinant targeted cytokine for cancer immunotherapy.
Front Pharmacol
; 15: 1380000, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38887559
6.
Deregulated Ras signaling in developmental disorders: new tricks for an old dog.
Curr Opin Genet Dev
; 17(1): 15-22, 2007 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-17208427
7.
Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back.
Am J Med Genet A
; 152A(1): 4-24, 2010 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-20014119
8.
Mutation analysis in Costello syndrome: functional and structural characterization of the HRAS p.Lys117Arg mutation.
Hum Mutat
; 29(2): 232-9, 2008 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-17979197
9.
De novo HRAS and KRAS mutations in two siblings with short stature and neuro-cardio-facio-cutaneous features.
J Med Genet
; 44(7): e84, 2007 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-17601930
10.
Methods for PTEN in Stem Cells and Cancer Stem Cells.
Methods Mol Biol
; 1388: 233-85, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27033080
11.
Targeting the MYC and PI3K pathways eliminates leukemia-initiating cells in T-cell acute lymphoblastic leukemia.
Cancer Res
; 74(23): 7048-59, 2014 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25287161
12.
De novo HRAS and KRAS mutations in two siblings with short stature and neuro-cardio-facio-cutaneous features.
BMJ Case Rep
; 20092009.
Artigo
Inglês
| MEDLINE | ID: mdl-21686750
13.
Biochemical and functional characterization of germ line KRAS mutations.
Mol Cell Biol
; 27(22): 7765-70, 2007 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-17875937
14.
Germline mutations in components of the Ras signaling pathway in Noonan syndrome and related disorders.
Cell Cycle
; 5(15): 1607-11, 2006 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-16921267
15.
Functional analysis of leukemia-associated PTPN11 mutations in primary hematopoietic cells.
Blood
; 106(1): 311-7, 2005 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-15761018
16.
Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis.
Blood
; 103(6): 2325-31, 2004 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-14644997