Detalhe da pesquisa
1.
Brain and visceral gene editing of mucopolysaccharidosis I mice by nasal delivery of the CRISPR/Cas9 system.
J Gene Med
; 24(4): e3410, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35032067
2.
Optimization of Coumarins Extraction from Pterocaulon balansae by Box-Behnken Design and Anti-Trichomonas vaginalis Activity.
Planta Med
; 87(6): 480-488, 2021 May.
Artigo
Inglês
| MEDLINE | ID: mdl-33578433
3.
Neonatal nonviral gene editing with the CRISPR/Cas9 system improves some cardiovascular, respiratory, and bone disease features of the mucopolysaccharidosis I phenotype in mice.
Gene Ther
; 27(1-2): 74-84, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31827259
4.
In vitro protective effect of topical nanoemulgels containing Brazilian red propolis benzophenones against UV-induced skin damage.
Photochem Photobiol Sci
; 19(10): 1460-1469, 2020 Oct 14.
Artigo
Inglês
| MEDLINE | ID: mdl-33026028
5.
Nasal Administration of Cationic Nanoemulsions as Nucleic Acids Delivery Systems Aiming at Mucopolysaccharidosis Type I Gene Therapy.
Pharm Res
; 35(11): 221, 2018 Sep 26.
Artigo
Inglês
| MEDLINE | ID: mdl-30259180
6.
Skin Permeation and Oxidative Protection Effect of Soybean Isoflavones from Topical Nanoemulsions-a Comparative Study of Extracts and Pure Compounds.
AAPS PharmSciTech
; 19(7): 3029-3039, 2018 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-30084071
7.
Regulatory Framework, Challenges, and Initial Strategic Planning for Advanced Therapy Products (PTAs) Development in Brazil.
Ther Innov Regul Sci
; 58(1): 21-33, 2024 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37815738
8.
Topical Nanoemulsions as Delivery Systems for Green Extracts of Pterocaulon balansae Aiming at the Treatment of Sporotrichosis.
Pharmaceutics
; 16(4)2024 Apr 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38675153
9.
Laronidase-loaded liposomes reach the brain and other hard-to-treat organs after noninvasive nasal administration.
Int J Pharm
; 660: 124355, 2024 Jun 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38897489
10.
Nasal administration of a temozolomide-loaded thermoresponsive nanoemulsion reduces tumor growth in a preclinical glioblastoma model.
J Control Release
; 355: 343-357, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36731799
11.
Drug Repositioning Applied to Cardiovascular Disease in Mucopolysaccharidosis.
Life (Basel)
; 12(12)2022 Dec 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36556450
12.
Gene editing strategies to treat lysosomal disorders: The example of mucopolysaccharidoses.
Adv Drug Deliv Rev
; 191: 114616, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36356930
13.
Genome editing in mucopolysaccharidoses and mucolipidoses.
Prog Mol Biol Transl Sci
; 182: 327-351, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34175047
14.
Gene Therapy of Mucopolysaccharidosis Type I Mice: Repeated Administrations and Safety Assessment of pIDUA/Nanoemulsion Complexes.
Curr Gene Ther
; 21(5): 464-471, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33573568
15.
In Situ Gene Therapy.
Curr Gene Ther
; 21(5): 406-430, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33949931
16.
Biodistribution of Transplanted Hematopoietic Precursor Cells Injected Through Different Administration Routes in Newborn Mice.
Hum Gene Ther
; 32(9-10): 495-505, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33632008
17.
Chitosan-coated rosmarinic acid nanoemulsion nasal administration protects against LPS-induced memory deficit, neuroinflammation, and oxidative stress in Wistar rats.
Neurochem Int
; 141: 104875, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33039443
18.
Box Behnken design of siRNA-loaded liposomes for the treatment of a murine model of ocular keratitis caused by Acanthamoeba.
Colloids Surf B Biointerfaces
; 173: 725-732, 2019 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30384269
19.
An overview of the neuroprotective potential of rosmarinic acid and its association with nanotechnology-based delivery systems: A novel approach to treating neurodegenerative disorders.
Neurochem Int
; 122: 47-58, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30439384
20.
Physicochemical properties of cationic nanoemulsions and liposomes obtained by microfluidization complexed with a single plasmid or along with an oligonucleotide: Implications for CRISPR/Cas technology.
J Colloid Interface Sci
; 530: 243-255, 2018 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29982016