Detalhe da pesquisa
1.
Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains.
Cell
; 175(7): 1842-1855.e16, 2018 12 13.
Artigo
Inglês
| MEDLINE | ID: mdl-30449618
2.
Targeted perturbation of signaling-driven condensates.
Mol Cell
; 83(22): 4141-4157.e11, 2023 Nov 16.
Artigo
Inglês
| MEDLINE | ID: mdl-37977121
3.
Enhancer Features that Drive Formation of Transcriptional Condensates.
Mol Cell
; 75(3): 549-561.e7, 2019 08 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31398323
4.
Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes.
Mol Cell
; 76(5): 753-766.e6, 2019 12 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31563432
5.
MeCP2 links heterochromatin condensates and neurodevelopmental disease.
Nature
; 586(7829): 440-444, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32698189
6.
Convergence of developmental and oncogenic signaling pathways at transcriptional super-enhancers.
Mol Cell
; 58(2): 362-70, 2015 Apr 16.
Artigo
Inglês
| MEDLINE | ID: mdl-25801169
7.
Protein Condensation in the Nuclear Receptor Family; Implications for Transcriptional Output.
Adv Exp Med Biol
; 1390: 243-253, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36107323
8.
Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF.
EMBO J
; 33(2): 146-56, 2014 Jan 13.
Artigo
Inglês
| MEDLINE | ID: mdl-24413017
9.
Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis.
EMBO J
; 32(20): 2708-21, 2013 Oct 16.
Artigo
Inglês
| MEDLINE | ID: mdl-24045232
10.
Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins.
EMBO J
; 31(12): 2685-96, 2012 Jun 13.
Artigo
Inglês
| MEDLINE | ID: mdl-22617424
11.
Integrated genome-wide analysis of transcription factor occupancy, RNA polymerase II binding and steady-state RNA levels identify differentially regulated functional gene classes.
Nucleic Acids Res
; 40(1): 148-58, 2012 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-21914722
12.
TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions.
Proc Natl Acad Sci U S A
; 107(34): 15157-62, 2010 Aug 24.
Artigo
Inglês
| MEDLINE | ID: mdl-20696899
13.
Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism.
Cell Rep
; 23(2): 349-360, 2018 Apr 10.
Artigo
Inglês
| MEDLINE | ID: mdl-29641996
14.
Coactivator condensation at super-enhancers links phase separation and gene control.
Science
; 361(6400)2018 07 27.
Artigo
Inglês
| MEDLINE | ID: mdl-29930091
15.
Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts.
Cell Stem Cell
; 16(2): 158-70, 2015 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-25620640
16.
Robust cre-mediated recombination in small intestinal stem cells utilizing the olfm4 locus.
Stem Cell Reports
; 3(2): 234-41, 2014 Aug 12.
Artigo
Inglês
| MEDLINE | ID: mdl-25254337
17.
DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus.
Genome Biol
; 14(5): R50, 2013 May 28.
Artigo
Inglês
| MEDLINE | ID: mdl-23714178
18.
Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles.
PLoS One
; 5(11): e15092, 2010 Nov 30.
Artigo
Inglês
| MEDLINE | ID: mdl-21152096