Detalhe da pesquisa
1.
Dioxygen, an unexpected carbonic anhydrase ligand.
J Enzyme Inhib Med Chem
; 33(1): 999-1005, 2018 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-29806484
2.
Sulphonamide inhibition studies of the ß-carbonic anhydrase from the bacterial pathogen Clostridium perfringens.
J Enzyme Inhib Med Chem
; 33(1): 31-36, 2018 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-29098923
3.
The crystal structures of native hydroquinone 1,2-dioxygenase from Sphingomonas sp. TTNP3 and of substrate and inhibitor complexes.
Biochim Biophys Acta Proteins Proteom
; 1865(5): 520-530, 2017 May.
Artigo
Inglês
| MEDLINE | ID: mdl-28232026
4.
1,3-Oxazole-based selective picomolar inhibitors of cytosolic human carbonic anhydrase II alleviate ocular hypertension in rabbits: Potency is supported by X-ray crystallography of two leads.
Bioorg Med Chem
; 25(17): 4560-4565, 2017 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28728897
5.
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea.
Bioorg Med Chem Lett
; 26(4): 1253-9, 2016 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26832216
6.
Fluorescent sulfonamide carbonic anhydrase inhibitors incorporating 1,2,3-triazole moieties: Kinetic and X-ray crystallographic studies.
Bioorg Med Chem
; 24(2): 104-12, 2016 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26682703
7.
Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors.
Bioorg Med Chem
; 24(16): 3643-8, 2016 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27316543
8.
Synthesis and inhibition potency of novel ureido benzenesulfonamides incorporating GABA as tumor-associated carbonic anhydrase IX and XII inhibitors.
J Enzyme Inhib Med Chem
; 31(2): 205-11, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-25792500
9.
Dithiocarbamates with potent inhibitory activity against the Saccharomyces cerevisiae ß-carbonic anhydrase.
J Enzyme Inhib Med Chem
; 31(1): 132-6, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-25669351
10.
The effect of caffeic acid phenethyl ester (CAPE) on metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, lactoperoxidase, and carbonic anhydrase isoenzymes I, II, IX, and XII.
J Enzyme Inhib Med Chem
; 31(6): 1095-101, 2016 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26453427
11.
Rosmarinic acid inhibits some metabolic enzymes including glutathione S-transferase, lactoperoxidase, acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase isoenzymes.
J Enzyme Inhib Med Chem
; 31(6): 1698-702, 2016 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26864149
12.
Polyamines and α-Carbonic Anhydrases.
Molecules
; 21(12)2016 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27983696
13.
Structural basis for the substrate specificity and the absence of dehalogenation activity in 2-chloromuconate cycloisomerase from Rhodococcus opacus 1CP.
Biochim Biophys Acta
; 1844(9): 1541-9, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24768773
14.
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.
Bioorg Med Chem Lett
; 25(17): 3550-5, 2015 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26174556
15.
6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA.
Org Biomol Chem
; 13(1): 77-80, 2015 Jan 07.
Artigo
Inglês
| MEDLINE | ID: mdl-25373598
16.
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune.
Bioorg Med Chem
; 23(8): 1728-34, 2015 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25773015
17.
Cyclodextrin complexation highly enhances efficacy of arylsulfonylureido benzenesulfonamide carbonic anhydrase inhibitors as a topical antiglaucoma agents.
Bioorg Med Chem
; 23(18): 6223-7, 2015 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26319622
18.
A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects.
Bioorg Med Chem
; 23(8): 1828-40, 2015 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25766630
19.
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.
Bioorg Med Chem
; 23(15): 4405-4409, 2015 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26145820
20.
Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action.
Bioorg Med Chem
; 23(10): 2368-76, 2015 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25846066