Pesquisa | Secretaria de Estado da Saúde

1.

Pembrolizumab or placebo with chemoradiotherapy followed by pembrolizumab or placebo for newly diagnosed, high-risk, locally advanced cervical cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): a randomised, double-blind, phase 3 clinical trial.

Lorusso, Domenica; Xiang, Yang; Hasegawa, Kosei; Scambia, Giovanni; Leiva, Manuel; Ramos-Elias, Pier; Acevedo, Alejandro; Sukhin, Vladyslav; Cloven, Noelle; Pereira de Santana Gomes, Andrea J; Contreras Mejía, Fernando; Reiss, Ari; Ayhan, Ali; Lee, Jung-Yun; Saevets, Valeriya; Zagouri, Flora; Gilbert, Lucy; Sehouli, Jalid; Tharavichitkul, Ekkasit; Lindemann, Kristina; Lazzari, Roberta; Chang, Chih-Long; Lampé, Rudolf; Zhu, Hong; Oaknin, Ana; Christiaens, Melissa; Polterauer, Stephan; Usami, Tomoka; Li, Kan; Yamada, Karin; Toker, Sarper; Keefe, Stephen M; Pignata, Sandro; Duska, Linda R.

Lancet ; 403(10434): 1341-1350, 2024 Apr 06.

Artigo Inglês | MEDLINE | ID: mdl-38521086

2.

Fibroblast Growth Factor Receptors and Ligands in Context of Bevacizumab Response in Ovarian Carcinoma: An Exploratory Analysis of AGO-OVAR11/ICON-7.

Heublein, Sabine; Pfisterer, Jacobus; du Bois, Andreas; Anglesio, Michael; Aminossadati, Behnaz; Bhatti, Irfan; Sehouli, Jalid; Wimberger, Pauline; Schochter, Fabienne; Hilpert, Felix; Hillemanns, Peter; Kalder, Matthias; Schroeder, Willibald; Mahner, Sven; Burges, Alexander; Canzler, Ulrich; Gropp-Meier, Martina; Jackisch, Christian; Harter, Philipp; Kommoss, Stefan; Marmé, Frederik.

Lab Invest ; 104(4): 100321, 2024 Apr.

Artigo Inglês | MEDLINE | ID: mdl-38154497

3.

Loss of copy numbers of retrotransposons (HERVK) on chromosome 7p11.2 impacts EGFR (Epidermal Growth Factor Receptor)-induced phenotypes for platinum sensitivity and long-term survival in ovarian cancer-A study from the OVCAD consortium.

Fromhage, Gesa; Obermayr, Eva; Bednarz-Knoll, Natalia; Van Gorp, Toon; Welsch, Eva; Polterauer, Stephan; Braicu, Elena Ioana; Mahner, Sven; Sehouli, Jalid; Vergote, Ignace; Concin, Nicole; Kurtz, Stefan; Steinbiss, Sascha; Torge, Antje; Zeillinger, Robert; Wölber, Linn; Brandt, Burkhard.

Int J Cancer ; 2024 May 06.

Artigo Inglês | MEDLINE | ID: mdl-38709956

4.

Gene expression markers in peripheral blood and outcome in patients with platinum-resistant ovarian cancer: A study of the European GANNET53 consortium.

Obermayr, Eva; Mohr, Thomas; Schuster, Eva; Braicu, Elena Ioana; Taube, Eliane; Sehouli, Jalid; Vergote, Ignace; Pujade-Lauraine, Eric; Ray-Coquard, Isabelle; Harter, Philipp; Wimberger, Pauline; Joly-Lobbedez, Florence; Mahner, Sven; Moll, Ute Martha; Concin, Nicole; Zeillinger, Robert.

Int J Cancer ; 2024 Apr 27.

Artigo Inglês | MEDLINE | ID: mdl-38676430

5.

AHRR and SFRP2 in primary versus recurrent high-grade serous ovarian carcinoma and their prognostic implication.

Monjé, Nanna; Dragomir, Mihnea P; Sinn, Bruno V; Hoffmann, Inga; Makhmut, Anuar; Simon, Tincy; Kunze, Catarina A; Ihlow, Jana; Schmitt, Wolfgang D; Pohl, Jonathan; Piwonski, Iris; Marchenko, Sofya; Keunecke, Carlotta; Calina, Teodor G; Tiso, Francesca; Kulbe, Hagen; Kreuzinger, Caroline; Cacsire Castillo-Tong, Dan; Sehouli, Jalid; Braicu, Elena I; Denkert, Carsten; Darb-Esfahani, Silvia; Kübler, Kirsten; Capper, David; Coscia, Fabian; Morkel, Markus; Horst, David; Sers, Christine; Taube, Eliane T.

Br J Cancer ; 130(8): 1249-1260, 2024 May.

Artigo Inglês | MEDLINE | ID: mdl-38361045

6.

Stable expansion of high-grade serous ovarian cancer organoids requires a low-Wnt environment.

Hoffmann, Karen; Berger, Hilmar; Kulbe, Hagen; Thillainadarasan, Sukanija; Mollenkopf, Hans-Joachim; Zemojtel, Tomasz; Taube, Eliane; Darb-Esfahani, Silvia; Mangler, Mandy; Sehouli, Jalid; Chekerov, Radoslav; Braicu, Elena I; Meyer, Thomas F; Kessler, Mirjana.

EMBO J ; 39(6): e104013, 2020 03 16.

Artigo Inglês | MEDLINE | ID: mdl-32009247

7.

Randomized Trial of Cytoreductive Surgery for Relapsed Ovarian Cancer.

Harter, Philipp; Sehouli, Jalid; Vergote, Ignace; Ferron, Gwenael; Reuss, Alexander; Meier, Werner; Greggi, Stefano; Mosgaard, Berit J; Selle, Frederic; Guyon, Frédéric; Pomel, Christophe; Lécuru, Fabrice; Zang, Rongyu; Avall-Lundqvist, Elisabeth; Kim, Jae-Weon; Ponce, Jordi; Raspagliesi, Francesco; Kristensen, Gunnar; Classe, Jean-Marc; Hillemanns, Peter; Jensen, Pernille; Hasenburg, Annette; Ghaem-Maghami, Sadaf; Mirza, Mansoor R; Lund, Bente; Reinthaller, Alexander; Santaballa, Ana; Olaitan, Adeola; Hilpert, Felix; du Bois, Andreas.

N Engl J Med ; 385(23): 2123-2131, 2021 12 02.

Artigo Inglês | MEDLINE | ID: mdl-34874631

8.

Accuracy of endometrial sampling in the diagnosis of endometrial cancer: a multicenter retrospective analysis of the JAGO-NOGGO.

Alwafai, Zaher; Beck, Maximilian Heinz; Fazeli, Sepideh; Gürtler, Kathleen; Kunz, Christine; Singhartinger, Juliane; Trojnarska, Dominika; Zocholl, Dario; Krankenberg, David Johannes; Blohmer, Jens-Uwe; Sehouli, Jalid; Pietzner, Klaus.

BMC Cancer ; 24(1): 380, 2024 Mar 25.

Artigo Inglês | MEDLINE | ID: mdl-38528468

9.

Hidden in plain sight - Survival consequences of baseline symptom burden in women with recurrent ovarian cancer.

Roncolato, Felicia; King, Madeleine T; O'Connell, Rachel L; Lee, Yeh Chen; Joly, Florence; Hilpert, Felix; Lanceley, Anne; Yoshida, Yoshio; Bryce, Jane; Donnellan, Paul; Oza, Amit; Avall-Lundqvist, Elisabeth; Berek, Jonathan S; Ledermann, Jonathan A; Berton, Dominique; Sehouli, Jalid; Kaminsky, Marie-Christine; Stockler, Martin R; Friedlander, Michael.

Gynecol Oncol ; 185: 128-137, 2024 Feb 26.

Artigo Inglês | MEDLINE | ID: mdl-38412736

10.

Health-related quality of life metrics as endpoints in surgical trials: hype or hope?

Armbrust, Robert; Davies-Oliveira, Jennifer; Sehouli, Jalid.

Int J Gynecol Cancer ; 34(3): 447-450, 2024 Mar 04.

Artigo Inglês | MEDLINE | ID: mdl-38438183

11.

ENGOT-EN20/GOG-3083/XPORT-EC-042 - A phase III, randomized, placebo-controlled, double-blind, multicenter trial of selinexor in maintenance therapy after systemic therapy for patients with p53 wild-type, advanced, or recurrent endometrial carcinoma: rationale, methods, and trial design.

Vergote, Ignace; Perez Fidalgo, Alejandro; Valabrega, Giorgio; Monk, Bradley J; Herzog, Thomas; Cibula, David; Colombo, Nicoletta; Pothuri, Bhavana; Sehouli, Jalid; Korach, Jacob; Barlin, Joyce; Papadimitriou, Christos A; van Gorp, Toon; Richardson, Debra; McCarthy, Michael; Antill, Yoland; Mirza, Mansoor Raza; Li, Kai; Kalyanapu, Pratheek; Slomovitz, Brian; Coleman, Robert L.

Int J Gynecol Cancer ; 2024 Apr 16.

Artigo Inglês | MEDLINE | ID: mdl-38627035

12.

Human papillomavirus prevalence in pregnant women living with human immunodeficiency virus infection: a scoping review of the literature.

Metz, Charlotte Kalinka; Skof, Anna Sophie; Henrich, Wolfgang; Sehouli, Jalid; Kaufmann, Andreas M; Rohr, Irena.

J Perinat Med ; 52(1): 1-13, 2024 Jan 29.

Artigo Inglês | MEDLINE | ID: mdl-37540166

13.

Training in obstetrics and gynecology between reality and vision: results of a JAGO-NOGGO survey in 601 physicians (NOGGO-Monitor-12 trial).

von Waldenfels, Gabriel; Beck, Maximilian Heinz; Semmler, Janina; Gerber, Annika; Hennigs, André; Vochem, Ruth; Blohmer, Jens-Uwe; Schmalfeldt, Barbara; Pietzner, Klaus; Sehouli, Jalid.

Arch Gynecol Obstet ; 2024 Apr 16.

Artigo Inglês | MEDLINE | ID: mdl-38625545

14.

Ovarian cancer management in an ESGO ovarian cancer center of excellence: a systematic case study of the interprofessional and interdisciplinary interaction.

Krankenberg, David J; Muallem, Mustafa Zelal; Pietzner, Klaus; Chekerov, Radoslav; Armbrust, Robert; Beteta, Carmen; Schöning, Wenzel; Lee, Marlene; Klews, Julia; Sehouli, Jalid.

Arch Gynecol Obstet ; 2024 Mar 20.

Artigo Inglês | MEDLINE | ID: mdl-38507090

15.

Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer: A Multicenter Retrospective Study by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) Consortium.

Glajzer, Jacek; Castillo-Tong, Dan Cacsire; Richter, Rolf; Vergote, Ignace; Kulbe, Hagen; Vanderstichele, Adriaan; Ruscito, Ilary; Trillsch, Fabian; Mustea, Alexander; Kreuzinger, Caroline; Gourley, Charlie; Gabra, Hani; Taube, Eliane T; Dorigo, Oliver; Horst, David; Keunecke, Carlotta; Baum, Joanna; Angelotti, Timothy; Sehouli, Jalid; Braicu, Elena Ioana.

Ann Surg Oncol ; 30(1): 35-45, 2023 Jan.

Artigo Inglês | MEDLINE | ID: mdl-36085390

16.

Lurbinectedin in patients with pretreated endometrial cancer: results from a phase 2 basket clinical trial and exploratory translational study.

Kristeleit, Rebecca; Leary, Alexandra; Delord, Jean Pierre; Moreno, Victor; Oaknin, Ana; Castellano, Daniel; Shappiro, Geoffrey I; Fernández, Cristian; Kahatt, Carmen; Alfaro, Vicente; Siguero, Mariano; Rueda, Daniel; Zeaiter, Ali; Awada, Ahmad; Santaballa, Ana; Zaman, Khalil; Sehouli, Jalid; Subbiah, Vivek.

Invest New Drugs ; 41(5): 677-687, 2023 10.

Artigo Inglês | MEDLINE | ID: mdl-37556023

17.

Randomized phase II trial of farletuzumab plus chemotherapy versus placebo plus chemotherapy in low CA-125 platinum-sensitive ovarian cancer.

Herzog, Thomas J; Pignata, Sandro; Ghamande, Sharad A; Rubio, Maria-Jesús; Fujiwara, Keiichi; Vulsteke, Christof; Armstrong, Deborah K; Sehouli, Jalid; Coleman, Robert L; Gabra, Hani; Scambia, Giovanni; Monk, Bradley J; Arranz, José A; Ushijima, Kimio; Hanna, Rabbie; Zamagni, Claudio; Wenham, Robert M; González-Martín, Antionio; Slomovitz, Brian; Jia, Yan; Ramsay, Lisa; Tewari, Krishnansu S; Weil, Susan C; Vergote, Ignace B.

Gynecol Oncol ; 170: 300-308, 2023 03.

Artigo Inglês | MEDLINE | ID: mdl-36758420

18.

Overall survival and patient-reported outcome results from the placebo-controlled randomized phase III IMagyn050/GOG 3015/ENGOT-OV39 trial of atezolizumab for newly diagnosed stage III/IV ovarian cancer.

Pignata, Sandro; Bookman, Michael; Sehouli, Jalid; Miller, Austin; Penson, Richard T; Taskiran, Cagatay; Anderson, Charles; Hietanen, Sakari; Myers, Tashanna; Madry, Radoslaw; Willmott, Lyndsay; Lortholary, Alain; Thomes-Pepin, Jessica; Aghajanian, Carol; McCourt, Carolyn; Stuckey, Ashley; Wu, Xiaohua; Nishio, Shin; Copeland, Larry J; He, Yvette; Molinero, Luciana; Patel, Sheetal; Lin, Yvonne G; Khor, Victor K; Moore, Kathleen N.

Gynecol Oncol ; 177: 20-31, 2023 Oct.

Artigo Inglês | MEDLINE | ID: mdl-37625235

19.

Molecular determinants of clinical outcomes of pembrolizumab in recurrent ovarian cancer: Exploratory analysis of KEYNOTE-100.

Ledermann, Jonathan A; Shapira-Frommer, Ronnie; Santin, Alessandro D; Lisyanskaya, Alla S; Pignata, Sandro; Vergote, Ignace; Raspagliesi, Francesco; Sonke, Gabe S; Birrer, Michael; Provencher, Diane M; Sehouli, Jalid; Colombo, Nicoletta; González-Martín, Antonio; Oaknin, Ana; Ottevanger, P B; Rudaitis, Vilius; Kobie, Julie; Nebozhyn, Michael; Edmondson, Mackenzie; Sun, Yuan; Cristescu, Razvan; Jelinic, Petar; Keefe, Stephen M; Matulonis, Ursula A.

Gynecol Oncol ; 178: 119-129, 2023 Nov.

Artigo Inglês | MEDLINE | ID: mdl-37862791

20.

Treatment and survival of patients with malignant ovarian sex cord-stromal cell tumours: An analysis of the Arbeitsgemeinschaft für Gynäkologische Onkologie (AGO) study group CORSETT database.

Klar, Maximilian; Plett, Helmut; Harter, Philipp; Heitz, Florian; Kommoss, Stefan; Hartkopf, Andreas Daniel; Grube, Marcel; Roser, Eva; Sehouli, Jalid; Braicu, Iona; Czogalla, Bastian; Burges, Alexander; Bossart, Michaela; Hasanov, Mir Fuad; Link, Teresa; Staebler, Annette; Mayr, Doris; Buderath, Paul; Hasenburg, Annette.

J Surg Oncol ; 128(1): 111-118, 2023 Jul.

Artigo Inglês | MEDLINE | ID: mdl-36975108

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