Detalhe da pesquisa
1.
3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis.
Mol Cell
; 80(5): 828-844.e6, 2020 12 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33128871
2.
Simultaneous isolation of hormone receptor-positive breast cancer organoids and fibroblasts reveals stroma-mediated resistance mechanisms.
J Biol Chem
; 299(8): 105021, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37423299
3.
Fibroblast-tumor cell signaling limits HER2 kinase therapy response via activation of MTOR and antiapoptotic pathways.
Proc Natl Acad Sci U S A
; 117(28): 16500-16508, 2020 07 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32601199
4.
Identification of cancer genes that are independent of dominant proliferation and lineage programs.
Proc Natl Acad Sci U S A
; 114(52): E11276-E11284, 2017 12 26.
Artigo
Inglês
| MEDLINE | ID: mdl-29229826
5.
Identification of genes that regulate epithelial cell migration using an siRNA screening approach.
Nat Cell Biol
; 10(9): 1027-38, 2008 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-19160483
6.
Evidence for a multipotent mammary progenitor with pregnancy-specific activity.
Breast Cancer Res
; 15(4): R65, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23947835
7.
Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells.
Proc Natl Acad Sci U S A
; 107(11): 5012-7, 2010 Mar 16.
Artigo
Inglês
| MEDLINE | ID: mdl-20194747
8.
Glutathione supports lipid abundance in vivo.
bioRxiv
; 2023 Feb 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36798186
9.
Statistical methods for analysis of high-throughput RNA interference screens.
Nat Methods
; 6(8): 569-75, 2009 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-19644458
10.
Lineage-specific silencing of PSAT1 induces serine auxotrophy and sensitivity to dietary serine starvation in luminal breast tumors.
Cell Rep
; 38(3): 110278, 2022 01 18.
Artigo
Inglês
| MEDLINE | ID: mdl-35045283
11.
Clonal populations of a human TNBC model display significant functional heterogeneity and divergent growth dynamics in distinct contexts.
Oncogene
; 41(1): 112-124, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34703030
12.
A human breast atlas integrating single-cell proteomics and transcriptomics.
Dev Cell
; 57(11): 1400-1420.e7, 2022 06 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35617956
13.
Clinical evaluation of BCL-2/XL levels pre- and post- HER2-targeted therapy.
PLoS One
; 16(5): e0251163, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33951110
14.
Screensaver: an open source lab information management system (LIMS) for high throughput screening facilities.
BMC Bioinformatics
; 11: 260, 2010 May 18.
Artigo
Inglês
| MEDLINE | ID: mdl-20482787
15.
Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing.
Cell Rep
; 33(13): 108566, 2020 12 29.
Artigo
Inglês
| MEDLINE | ID: mdl-33378681
16.
Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages.
Nat Commun
; 11(1): 1711, 2020 04 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32249764
17.
Transient commensal clonal interactions can drive tumor metastasis.
Nat Commun
; 11(1): 5799, 2020 11 16.
Artigo
Inglês
| MEDLINE | ID: mdl-33199705
18.
Direct stimulation of NADP+ synthesis through Akt-mediated phosphorylation of NAD kinase.
Science
; 363(6431): 1088-1092, 2019 03 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30846598
19.
Combined MEK and BCL-2/XL Inhibition Is Effective in High-Grade Serous Ovarian Cancer Patient-Derived Xenograft Models and BIM Levels Are Predictive of Responsiveness.
Mol Cancer Ther
; 18(3): 642-655, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30679390
20.
Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion.
Cell Metab
; 29(5): 1166-1181.e6, 2019 05 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30799286