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Expert Rev Gastroenterol Hepatol ; 15(10): 1191-1200, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-33706616

RESUMO

Objectives: Since there is increasing number of patients with cirrhosis who require the bariatric procedure due to obesity and obesity-related nonalcoholic steatohepatitis fibrosis, we evaluate the effect of cirrhosis on post-bariatric surgery outcomes.Methods: 2011-2017 National Inpatient Sample was used to isolate bariatric cases, which were stratified by cirrhosis; controls were propensity-score matched to cases and compared to endpoints: mortality, length of stay (LOS), costs, and postoperative complications.Results: From 190,753 patients undergoing bariatric surgery, there were 957 with cirrhosis and 957 matched controls. There was no difference in mortality (0.94 vs 0.52% p = 0.42, OR 1.81 95%CI 0.60-5.41); however, cirrhosis patients had higher LOS (3.36 vs 2.89d p = 0.002), costs ($68,671 vs $61,301 p < 0.001), and bleeding (2.09 vs 0.72% p < 0.001, OR 2.95 95%CI 1.89-4.61). In multivariate, there was no difference in mortality (p = 0.330, aOR 1.73 95%CI 0.58-5.19). In subgroup comparison of cirrhosis patients, those with decompensated cirrhosis had higher mortality (7.69 vs 0.94% p < 0.001, OR 8.78 95%CI 3.41-22.59).Conclusion: The results of this study show compensated cirrhosis does not pose an increased risk toward post-bariatric surgery mortality; however, hepatic decompensation increases the postsurgical risks.


Assuntos
Cirurgia Bariátrica , Cirrose Hepática/complicações , Obesidade Mórbida/cirurgia , Complicações Pós-Operatórias/etiologia , Adolescente , Adulto , Idoso , Cirurgia Bariátrica/mortalidade , Estudos de Casos e Controles , Bases de Dados Factuais , Feminino , Humanos , Tempo de Internação/estatística & dados numéricos , Cirrose Hepática/mortalidade , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Obesidade Mórbida/complicações , Obesidade Mórbida/mortalidade , Razão de Chances , Complicações Pós-Operatórias/epidemiologia , Pontuação de Propensão , Fatores de Risco , Resultado do Tratamento , Adulto Jovem
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