Detalhe da pesquisa
1.
Anal intraepithelial neoplasia screening in patients with human immunodeficiency virus infection.
Rev Esp Enferm Dig
; 114(12): 713-718, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35285660
2.
Development and in vitro/in vivo evaluation of a novel benznidazole liquid dosage form using a quality-by-design approach.
Trop Med Int Health
; 22(12): 1514-1522, 2017 12.
Artigo
Inglês
| MEDLINE | ID: mdl-28944986
3.
Glycosomal bromodomain factor 1 from Trypanosoma cruzi enhances trypomastigote cell infection and intracellular amastigote growth.
Biochem J
; 473(1): 73-85, 2016 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26500280
4.
Trypanosoma cruzi bromodomain factor 3 binds acetylated α-tubulin and concentrates in the flagellum during metacyclogenesis.
Eukaryot Cell
; 13(6): 822-31, 2014 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-24747213
5.
Construction of three new Gateway® expression plasmids for Trypanosoma cruzi.
Mem Inst Oswaldo Cruz
; 109(8): 1081-5, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-25424446
6.
Deciphering Divergent Trypanosomatid Nuclear Complexes by Analyzing Interactomic Datasets with AlphaFold2 and Genetic Approaches.
ACS Infect Dis
; 9(6): 1267-1282, 2023 06 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37167453
7.
Lysine acetylation: elucidating the components of an emerging global signaling pathway in trypanosomes.
J Biomed Biotechnol
; 2012: 452934, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-23093844
8.
Update on the Biological Relevance of Lysine Acetylation as a Novel Drug Target in Trypanosomatids.
Curr Med Chem
; 29(20): 3638-3659, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-34825865
9.
Essential Bromodomain TcBDF2 as a Drug Target against Chagas Disease.
ACS Infect Dis
; 8(5): 1062-1074, 2022 05 13.
Artigo
Inglês
| MEDLINE | ID: mdl-35482332
10.
In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing ß-galactosidase.
J Vis Exp
; (177)2021 11 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34806703
11.
Alpha-Tubulin Acetylation in Trypanosoma cruzi: A Dynamic Instability of Microtubules Is Required for Replication and Cell Cycle Progression.
Front Cell Infect Microbiol
; 11: 642271, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33777851
12.
Trypanosoma cruzi TBP shows preference for C/G-rich DNA sequences in vitro.
Exp Parasitol
; 124(3): 346-9, 2010 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-19931528
13.
Aim for the Readers! Bromodomains As New Targets Against Chagas' Disease.
Curr Med Chem
; 26(36): 6544-6563, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30378479
14.
Overexpression of Trypanosoma cruzi High Mobility Group B protein (TcHMGB) alters the nuclear structure, impairs cytokinesis and reduces the parasite infectivity.
Sci Rep
; 9(1): 192, 2019 01 17.
Artigo
Inglês
| MEDLINE | ID: mdl-30655631
15.
Discovery of a Biologically Active Bromodomain Inhibitor by Target-Directed Dynamic Combinatorial Chemistry.
ACS Med Chem Lett
; 9(10): 1002-1006, 2018 Oct 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30344907
16.
A Bioactive Trypanosoma cruzi Bromodomain Inhibitor from Chemically Engineered Extracts.
ACS Comb Sci
; 20(4): 220-228, 2018 04 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29481050
17.
Antitrypanosomal and antileishmanial activity of prenyl-1,2,3-triazoles.
Medchemcomm
; 8(5): 1015-1021, 2017 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28993794
18.
Development of parenteral formulations and evaluation of the biological activity of the trypanocide drug benznidazole.
Int J Pharm
; 307(2): 239-43, 2006 Jan 13.
Artigo
Inglês
| MEDLINE | ID: mdl-16293378
19.
Overexpression of bromodomain factor 3 in Trypanosoma cruzi (TcBDF3) affects differentiation of the parasite and protects it against bromodomain inhibitors.
FEBS J
; 283(11): 2051-66, 2016 06.
Artigo
Inglês
| MEDLINE | ID: mdl-27007774
20.
Overexpression of cytoplasmic TcSIR2RP1 and mitochondrial TcSIR2RP3 impacts on Trypanosoma cruzi growth and cell invasion.
PLoS Negl Trop Dis
; 9(4): e0003725, 2015 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-25875650