RESUMO
Idiopathic neutrophilic eccrine hidradenitis is usually observed in healthy children with tender erythematous nodules on the soles or palms. We report a case of a 26-year-old man with a painful erythematous swollen patch on both hands and feet. His symptom recurred once monthly over 2 years; thus, he visited Orthopedics. However, no bony abnormality was identified. We performed a skin biopsy on an erythematous indurated patch on his right sole. Histopathological findings indicated neutrophilic eccrine hidradenitis. After 2 weeks of treatment with oral colchicine, his symptom resolved, and no relapses were observed during follow-up. Only a few case reports describe idiopathic neutrophilic eccrine hidradenitis in adults, which is not associated with malignant hematological disease, solid cancer, and chemotherapy. Conventional treatment comprises bed-rest and the administration of topical steroids. Colchicine can be a good treatment option for adults with severe or recurrent idiopathic neutrophilic eccrine hidradenitis.
Assuntos
Adulto , Criança , Humanos , Biópsia , Colchicina , Tratamento Farmacológico , Seguimentos , Pé , Mãos , Doenças Hematológicas , Hidradenite , Neutrófilos , Ortopedia , Recidiva , Pele , EsteroidesRESUMO
Dermatofibrosarcoma protuberans (DFSP) is a slow growing low-grade cutaneous sarcoma. Local recurrence after excision is common due to the poorly defined periphery that renders histological control of surgical margin difficult, Mohs micrographic surgery is the optimal method for treatment. A 41 years old male patient, who had a previous history of DFSP, came to our dermatology clinic for evaluation of an asymptomatic firm flesh-colored nodule on the forehead. Total excision biopsy was done and the mass was histologically proved as DFSP. Wide excision with reconstruction was performed and showed no sign of recurrence till 18-month follow up. Local recurrence is known to be common for DFSP but a new visible lesion distant from the initial site may be confused as a de novo lesion or a benign neoplasm especially in scalp area, and thus interrupt early detection of DFSP. Herein, we report a case of recurrent DFSP of scalp which recurred distant from the original lesion.
Assuntos
Humanos , Masculino , Biópsia , Dermatofibrossarcoma , Dermatologia , Seguimentos , Testa , Métodos , Cirurgia de Mohs , Recidiva , Sarcoma , Couro CabeludoRESUMO
BACKGROUND: To meet the need for a subspecialized skin type system, the Baumann skin type (BST) system was proposed. OBJECTIVE: To evaluate the distribution of BST types and influencing factors among Korean women. METHODS: BST questionnaires were administered to 1,000 Korean women. The possible responses were as follows: oily (O) or dry (D), sensitive (S) or resistant (R), pigmented (P) or non-pigmented (N), and wrinkled (W) or tight (T). The correlations of the BST with the subjects' age, location, ultraviolet (UV) ray exposure, drinking and smoking habits, and blood type were assessed. RESULTS: The OSNT, DSNT, DRNT, and OSNW skin types were the most common skin types (55.3%). The O, S, P, and W types accounted for 46.6%, 68.8%, 23.2%, and 31.9%, respectively. The proportion of the O and S type was the highest in Gyeongsangbuk-do (55.0%) and Seoul (77.2%). The proportion of the P and W type was the highest in Gyeongsangbuk-do (33.0%) and Chungcheong-do (39.0%). The O type decreased in the higher age group, whereas the P and W type showed a reversed tendency. In smokers, the proportion of W type was significantly higher than in the non-smokers (66.3% vs. 24.1%, p<0.05). CONCLUSION: The 4 most common BST types were OSNT, DSNT, DRNT, and OSNW. In the comparison across the 4 BST parameters according to the age, region, smoking and drinking habits, occupation, blood type, and UV exposure, significant differences were observed. Individualized and customized skin care is required according to the personal skin type.
Assuntos
Feminino , Humanos , Ingestão de Líquidos , Ocupações , Seul , Higiene da Pele , Pele , Fumaça , Fumar , Inquéritos e QuestionáriosRESUMO
There are many therapeutic methods for treating vitiligo, including narrow-band UVB, topical corticosteroids, calcineurin inhibitors, excimer laser, and surgical methods, such as autologous epidermal grafting and dermabrasion. However, although various treatments have been tried, there is still no reliable treatment. Recently, there were several reports about the use of fractional laser combined with narrow-band (NB) UVB to treat vitiligo. A 33-year-old male patient presented with hypopigmented patch on lower right abdominal area. After being diagnosed with vitiligo, the patient underwent NB-UVB treatment and application of a topical agent for two years but failed to show response. To evaluate the efficacy of non-ablative fractional laser, a 1550-nm erbium:glass (Er:Glass) fractional laser was applied to whole area of the lesion. The area showed erythema and brown microscopic epidermal necrotic debris. Five days after the laser procedure, NB-UVB treatment with application of a topical agent was initiated once or twice a week, followed by pigmentation of the treated area . The fractional laser was reapplied three months later, and the patient is currently under observation and is still being treated with NB-UVB. We observed successful treatment of refractory vitiligo with the combination of non-ablative 1550-nm Er:Glass fractional laser, NB-UVB, and a topical agent. We consider non-ablative Er:Glass fractional laser as a favorable choice of treatment for refractory vitiligo.
Assuntos
Adulto , Humanos , Masculino , Corticosteroides , Inibidores de Calcineurina , Dermabrasão , Eritema , Lasers de Excimer , Pigmentação , Transplantes , VitiligoRESUMO
Recently, various modalities for noninvasive reduction of adipose tissue, including cryolipolysis, radiofrequency, low-level laser therapy, and high-intensity focused ultrasound, have become available. Among these modalities, cryolipolysisis can selectively target certain tissues rich in lipids. Many preclinical and clinical studies have established the safety and efficacy of cryolipolysis for noninvasive body contouring. However, it can lead to serious adverse effects when performed by untrained clinicians. Thus, to promote the proper and safe use of cyolipolysis, we have summarized the history, basic principles, and adverse effects of cyolipolysis.
Assuntos
Tecido Adiposo , Terapia com Luz de Baixa Intensidade , UltrassonografiaRESUMO
BACKGROUND: It is unclear how the usage of topical steroid agents affects skin barrier function. OBJECTIVE: In order to follow up on previous research into this topic, we sought to investigate the effects of a 3-week application of topical mometasone cream on the alteration of skin barrier function. METHODS: Twenty-six patients who had been clinically diagnosed with allergic contact dermatitis were enrolled. Topical mometasone cream was applied to the skin lesions. Clinical symptoms, transepidermal water loss (TEWL), corneometer unit, and pH value were measured on the initial visit, 1 week after treatment, and 3 weeks after treatment, and their values were compared. RESULTS: Clinical symptoms showed improvement after topical mometasone cream was applied (p0.05). CONCLUSION: This study found that treatment with topical mometasone cream for 3 weeks has no effect on skin barrier function. We believe that this research will help determine the optimal duration and dosage of topical steroid agents used for treating allergic contact dermatitis.
Assuntos
Humanos , Dermatite Alérgica de Contato , Dermatite de Contato , Seguimentos , Concentração de Íons de Hidrogênio , Pele , Furoato de MometasonaRESUMO
Leiomyosarcoma is a relatively rare, soft tissue sarcoma, derived from smooth muscle. Superficial or cutaneous leiomyosarcomas, which are rare and account for less than 3% of the cutaneous soft tissue sarcoma, are subdivided into two groups. according to the development site: a dermal form and a subcutaneous form. Although cutaneous leiomyosarcoma may occur anywhere on the body, there is a predilection for the extremities, especially the thighs. However, leiomyosarcoma of the sole is exceedingly rare. We present a case of cutaneous leiomyosarcoma on the sole.
Assuntos
Extremidades , Leiomiossarcoma , Músculo Liso , Sarcoma , Coxa da PernaRESUMO
Punctate palmoplantar keratoderma(PPK) is a rare disease, characterized by small, hard hyperkeratotic papules which are irregularly distributed on the palms and soles. PPK is an autosomal dominant disease with variable penetrance. We report a case of sporadic case of punctate palmoplantar keratoderma in a 26-year-old female patient.
Assuntos
Adulto , Feminino , Humanos , Ceratodermia Palmar e Plantar , Penetrância , Doenças RarasRESUMO
Angiolipomas are subcutaneous tumors composed of a mixture of adipocytes and blood vessels. The tumor resembles lipomas clinically, but develops in young adults, and favored sites for this tumor are the arms and the trunk. They are usually multiple, often painful or tender and tend to be small. There have been 4 reported cases of angiolipoma in Korea. But they are mostly few, small and tend to be limited in trunk or upper extremities. Then we report a case that the total number of the masses is over 100 and multiple isolated masses up to 12cm in size were found on the whole body. The treatment with triamcinolone intralesional injection in the only one mass showed partial response but the other trial with enoxaparin didn't.
Assuntos
Humanos , Adulto Jovem , Adipócitos , Angiolipoma , Braço , Vasos Sanguíneos , Enoxaparina , Injeções Intralesionais , Coreia (Geográfico) , Lipoma , Triancinolona , Extremidade SuperiorRESUMO
On histological examination, an epidermolytic hyperkeratosis was observed adjacent to follicular papules on the back of a 53-year-old man. It has been reported that incidental epidermolytic hyperkeratosis occur either within various lesion (epidermal neoplasm, melanocytic neoplasm, scars, and inflammatory conditions) or in the normal skin adjacent to the lesion. This patient participated in the Vietnam War for 2 years, and had had contact with defoliants. He was treated for multiple peripheral neuropathies and cerebral infarcts. In keratinocytes, 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD; Agent Orange) contained in defoliating agents is associated with altered patterns of keratinocyte differentiation. So, as a cause of incidental epidermolytic hyperkeratosis, defoliant contact could be suspected.
Assuntos
Humanos , Pessoa de Meia-Idade , Cicatriz , Hiperceratose Epidermolítica , Queratinócitos , Doenças do Sistema Nervoso Periférico , Pele , Dibenzodioxinas Policloradas , Veteranos , VietnãRESUMO
BACKGROUND: Acetone disrupts the cutaneous permeability barrier through the removal of stratum corneum lipids. This pertubation of barrier integrity stimulates a variety of homeostatic repair that ultimately results in the normalization of barrier function. OBJECT: To measure the effect of steroid on the barrier recovery of acetone applied skin. MATERIAL AND METHODS: The flank skin of 8~10 week old hairless mice was treated with acetone and then topical and systemic steroids were applied. Transepidermal water loss(TEWL) was checked after 0, 3, 6, 12 and 24 hours. Electron and light microscopic examination and ion capture cytochemistry were performed after 3, 6, 12 and 24 hours after systemic and topical steroids had been applied. RESULTS: The results were as follows ; 1) During 3~6 hours after experiment, the recovery rate of TEWL was most prominent in the group of acetone applied animal than other groups. 2) After 12 hours after acetone applied, formation of new stratum corneum was found in the groups of acetone applied or acetone applied skin with topical steroid application. But loss of stratum corneum was observed in the groups of high or low dose steroid injection. 3) Ruthenium tetroxide staining of acetone alone or topical steroid treated specimens after 12 hours experiment revealed that the lipid bilayer was partly impaired and fragmented. Intercellular spaces were widening and the lipid bilayer disappeared or was damaged in the groups of high or low dose steroid injection. 4) Six hours after acetone application, pattern of calcium distribution had been partially reestabilished in the group of acetone alone or topical steroid treated animals. But calcium content was still sparse and decreased from the stratum granulosum to basale in the groups of high or low dose steroid injection. CONCLUSION: In summary the present study demonstrates that steroid treatment acutely delays recovery rate of TEWL, inhibits normalization of calcium gradient or epidermal lipid synthesis that leads to abnormalities in permeability barrier homeostasis.
Assuntos
Animais , Camundongos , Acetona , Cálcio , Espaço Extracelular , Histocitoquímica , Homeostase , Bicamadas Lipídicas , Camundongos Pelados , Permeabilidade , Rutênio , Pele , EsteroidesRESUMO
A 9-year-old girl presented with fever, conjunctival injection, desquamation following erythema and edema of the fingers and toes, strawberry tongue, polymorphous rash and cervical lymphadenopathy. She showed palpable purpura on the lower extremities after 7 days of the onset of the above symptoms. She showed typical Henoch-Schonlein purpura concurrent with Kawasaki disease. There is no known report of a case of Henoch-Schonlein purpura concurrent with Kawasaki disease and evaluation of the same pathogenesis of the two diseases. We've got a clue from the facts that human parvovirus B19 could develope both of the diseases. But Human parvovirus B19 PCR was negative. We, herein, report an unusual case of Henoch-Schonlein purpura concurrent with Kawasaki disease.