Detalhe da pesquisa
1.
Development of a series of novel o-phenylenediamine-based indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.
Bioorg Med Chem Lett
; 28(4): 732-736, 2018 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29398543
2.
[2.2.1]-Bicyclic sultams as potent androgen receptor antagonists.
Bioorg Med Chem Lett
; 26(23): 5707-5711, 2016 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27836399
3.
BMS-871: a novel orally active pan-Notch inhibitor as an anticancer agent.
Bioorg Med Chem Lett
; 25(9): 1905-9, 2015 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25857941
4.
Chemically synthesized molecules with the targeting and effector functions of antibodies.
J Am Chem Soc
; 136(52): 18034-43, 2014 Dec 31.
Artigo
Inglês
| MEDLINE | ID: mdl-25514603
5.
Conformational-Analysis-Guided Discovery of 2,3-Disubstituted Pyridine IDO1 Inhibitors.
ACS Med Chem Lett
; 12(7): 1143-1150, 2021 Jul 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34267885
6.
Design and synthesis of 4-[3,5-dioxo-11-oxa-4,9-diazatricyclo[5.3.1.0(2,6)]undec-4-yl]-2-trifluoromethyl-benzonitriles as androgen receptor antagonists.
Bioorg Med Chem Lett
; 20(15): 4491-5, 2010 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20584610
7.
Identification and optimization of a novel series of [2.2.1]-oxabicyclo imide-based androgen receptor antagonists.
Bioorg Med Chem Lett
; 18(6): 1910-5, 2008 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-18291644
8.
Discovery of BMS-641988, a Novel Androgen Receptor Antagonist for the Treatment of Prostate Cancer.
ACS Med Chem Lett
; 6(8): 908-12, 2015 Aug 13.
Artigo
Inglês
| MEDLINE | ID: mdl-26288692
9.
Discovery of Clinical Candidate BMS-906024: A Potent Pan-Notch Inhibitor for the Treatment of Leukemia and Solid Tumors.
ACS Med Chem Lett
; 6(5): 523-7, 2015 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-26005526
10.
N-(cycloalkylamino)acyl-2-aminothiazole inhibitors of cyclin-dependent kinase 2. N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4- piperidinecarboxamide (BMS-387032), a highly efficacious and selective antitumor agent.
J Med Chem
; 47(7): 1719-28, 2004 Mar 25.
Artigo
Inglês
| MEDLINE | ID: mdl-15027863
11.
Discovery of aminothiazole inhibitors of cyclin-dependent kinase 2: synthesis, X-ray crystallographic analysis, and biological activities.
J Med Chem
; 45(18): 3905-27, 2002 Aug 29.
Artigo
Inglês
| MEDLINE | ID: mdl-12190313
12.
Correction to N-(Cycloalkylamino)acyl-2-aminothiazole Inhibitors of Cyclin-Dependent Kinase 2. N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide (BMS-387032), a Highly Efficacious and Selective Antitumor Agent.
J Med Chem
; 58(18): 7609, 2015 Sep 24.
Artigo
Inglês
| MEDLINE | ID: mdl-26328598
13.
Discovery of BMS-641988, a novel and potent inhibitor of androgen receptor signaling for the treatment of prostate cancer.
Cancer Res
; 69(16): 6522-30, 2009 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19654297
14.
Exogenous application of jasmonic acid induces volatile emissions in rice and enhances parasitism of Nilaparvata lugens eggs by the parasitoid Anagrus nilaparvatae.
J Chem Ecol
; 31(9): 1985-2002, 2005 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-16132208
15.
Structure based approach to the design of bicyclic-1H-isoindole-1,3(2H)-dione based androgen receptor antagonists.
Bioorg Med Chem Lett
; 15(2): 271-6, 2005 Jan 17.
Artigo
Inglês
| MEDLINE | ID: mdl-15603938
16.
1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases.
Bioorg Med Chem Lett
; 13(6): 1133-6, 2003 Mar 24.
Artigo
Inglês
| MEDLINE | ID: mdl-12643928
17.
1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases: highly potent 2,6-Difluorophenacyl analogues.
Bioorg Med Chem Lett
; 13(14): 2405-8, 2003 Jul 21.
Artigo
Inglês
| MEDLINE | ID: mdl-12824044
18.
The synthesis and evaluation of [2.2.1]-bicycloazahydantoins as androgen receptor antagonists.
Bioorg Med Chem Lett
; 14(24): 6107-11, 2004 Dec 20.
Artigo
Inglês
| MEDLINE | ID: mdl-15546739