Detalhe da pesquisa
1.
Emerging phosphodiesterase inhibitors for treatment of neurodegenerative diseases.
Med Res Rev
; 2024 Jan 27.
Artigo
Inglês
| MEDLINE | ID: mdl-38279990
2.
AAA237, an SKP2 inhibitor, suppresses glioblastoma by inducing BNIP3-dependent autophagy through the mTOR pathway.
Cancer Cell Int
; 24(1): 69, 2024 Feb 10.
Artigo
Inglês
| MEDLINE | ID: mdl-38341584
3.
Potential therapeutic medicines for renal fibrosis: Small-molecule compounds and natural products.
Bioorg Chem
; 143: 106999, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38035515
4.
Recent development of VEGFR small molecule inhibitors as anticancer agents: A patent review (2021-2023).
Bioorg Chem
; 146: 107278, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38484586
5.
S670, an amide derivative of 3-O-acetyl-11-keto-ß-boswellic acid, induces ferroptosis in human glioblastoma cells by generating ROS and inhibiting STX17-mediated fusion of autophagosome and lysosome.
Acta Pharmacol Sin
; 45(1): 209-222, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-37749236
6.
Historical perspectives and recent advances in small molecule ligands of selective/biased/multi-targeted µ/δ/κ opioid receptor (2019-2022).
Bioorg Chem
; 141: 106869, 2023 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37797454
7.
Advances in non-radioactive PSMA-targeted small molecule-drug conjugates in the treatment of prostate cancer.
Bioorg Chem
; 141: 106889, 2023 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37813074
8.
Recent research of BTK inhibitors: Methods of structural design, pharmacological activities, manmade derivatives and structure-activity relationship.
Bioorg Chem
; 138: 106577, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37178649
9.
New therapeutic approaches against pulmonary fibrosis.
Bioorg Chem
; 138: 106592, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37178650
10.
Anti-tumor effects of Skp2 inhibitor AAA-237 on NSCLC by arresting cell cycle at G0/G1 phase and inducing senescence.
Pharmacol Res
; 181: 106259, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35577307
11.
HDAC/JAK dual target inhibitors of cancer-related targets: The success of nonclearable linked pharmacophore mode.
Bioorg Chem
; 129: 106181, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36302332
12.
Preclinical assessment of histone deacetylase inhibitor quisinostat as a therapeutic agent against esophageal squamous cell carcinoma.
Invest New Drugs
; 37(4): 616-624, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30168013
13.
Recent Advances of Natural Polyphenols Activators for Keap1-Nrf2 Signaling Pathway.
Chem Biodivers
; 16(11): e1900400, 2019 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-31482617
14.
Design, Synthesis and in Vitro Tumor Cytotoxicity Evaluation of 3,5-Diamino-N-substituted Benzamide Derivatives as Novel GSK-3ß Small Molecule Inhibitors.
Chem Biodivers
; 16(9): e1900304, 2019 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-31338947
15.
Crystal Structures of Candida albicans Phosphodiesterase 2 and Implications for Its Biological Functions.
Biochemistry
; 57(42): 6070-6077, 2018 10 23.
Artigo
Inglês
| MEDLINE | ID: mdl-30231198
16.
[Genetic analysis of an infant with duplication 9q34 syndrome].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
; 35(3): 437-439, 2018 Jun 10.
Artigo
Chinês
| MEDLINE | ID: mdl-29896750
17.
Emerging targets and new small molecule therapies in Parkinson's disease treatment.
Bioorg Med Chem
; 24(7): 1419-30, 2016 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26935940
18.
Synthesis of C2-Symmetric Benzimidazolium Salts and Their Application in Palladium-Catalyzed Enantioselective Intramolecular α-Arylation of Amides.
Molecules
; 21(6)2016 Jun 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27338322
19.
Synthesis and Antitumor Evaluation of Novel 5-Hydrosulfonyl-1H-benzo[d]imidazol-2(3H)-one Derivatives.
Molecules
; 21(4): 516, 2016 Apr 20.
Artigo
Inglês
| MEDLINE | ID: mdl-27104509
20.
K2CO3-mediated synthesis of functionalised 4-substituted-2-amino-3-cyano-4H-chromenes via Michael-cyclization reactions.
Molecules
; 19(12): 19253-68, 2014 Nov 25.
Artigo
Inglês
| MEDLINE | ID: mdl-25429557