Detalhe da pesquisa
1.
The hERG channel activator, RPR260243, enhances protective IKr current early in the refractory period reducing arrhythmogenicity in zebrafish hearts.
Am J Physiol Heart Circ Physiol
; 319(2): H251-H261, 2020 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32559136
2.
Stabilization of the Activated hERG Channel Voltage Sensor by Depolarization Involves the S4-S5 Linker.
Biophys J
; 112(2): 300-312, 2017 Jan 24.
Artigo
Inglês
| MEDLINE | ID: mdl-28122216
3.
External protons destabilize the activated voltage sensor in hERG channels.
Eur Biophys J
; 43(2-3): 59-69, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24362825
4.
Proton block of the pore underlies the inhibition of hERG cardiac K+ channels during acidosis.
Am J Physiol Cell Physiol
; 302(12): C1797-806, 2012 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22517356
5.
A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel.
Neuron
; 109(2): 273-284.e4, 2021 01 20.
Artigo
Inglês
| MEDLINE | ID: mdl-33152265
6.
Modulation of hERG K+ Channel Deactivation by Voltage Sensor Relaxation.
Front Pharmacol
; 11: 139, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-32184724
7.
Extracellular protons accelerate hERG channel deactivation by destabilizing voltage sensor relaxation.
J Gen Physiol
; 151(2): 231-246, 2019 02 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30530765