Detalhe da pesquisa
1.
Ubiquitination at the lysine 27 residue of the Parkin ubiquitin-like domain is suggestive of a new mechanism of Parkin activation.
Hum Mol Genet
; 31(15): 2623-2638, 2022 08 17.
Artigo
Inglês
| MEDLINE | ID: mdl-35313349
2.
Syntaxin 17 regulates the localization and function of PGAM5 in mitochondrial division and mitophagy.
EMBO J
; 37(21)2018 11 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30237312
3.
α-Synuclein V15A Variant in Familial Parkinson's Disease Exhibits a Weaker Lipid-Binding Property.
Mov Disord
; 37(10): 2075-2085, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35894540
4.
Parkinson's disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling.
Proc Natl Acad Sci U S A
; 116(41): 20689-20699, 2019 10 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31548400
5.
Mutations in CHCHD2 cause α-synuclein aggregation.
Hum Mol Genet
; 28(23): 3895-3911, 2019 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31600778
6.
Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson's disease.
Hum Mol Genet
; 26(16): 3172-3185, 2017 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28541509
7.
Twin CHCH Proteins, CHCHD2, and CHCHD10: Key Molecules of Parkinson's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia.
Int J Mol Sci
; 20(4)2019 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-30791515
8.
PINK1-mediated phosphorylation of Parkin boosts Parkin activity in Drosophila.
PLoS Genet
; 10(6): e1004391, 2014 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-24901221
9.
Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering.
PLoS Genet
; 10(12): e1004861, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-25474007
10.
Lysine 63-linked polyubiquitination is dispensable for Parkin-mediated mitophagy.
J Biol Chem
; 289(48): 33131-6, 2014 Nov 28.
Artigo
Inglês
| MEDLINE | ID: mdl-25336644
11.
Parkinson disease-associated Leucine-rich repeat kinase regulates UNC-104-dependent axonal transport of Arl8-positive vesicles in Drosophila.
iScience
; 25(12): 105476, 2022 Dec 22.
Artigo
Inglês
| MEDLINE | ID: mdl-36404922
12.
Pathophysiological evaluation of the LRRK2 G2385R risk variant for Parkinson's disease.
NPJ Parkinsons Dis
; 8(1): 97, 2022 Aug 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35931783
13.
Monitoring PINK1-Parkin Signaling Using Dopaminergic Neurons from iPS Cells.
Methods Mol Biol
; 2322: 81-92, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34043195
14.
A Cell-Based High-Throughput Screening Identified Two Compounds that Enhance PINK1-Parkin Signaling.
iScience
; 23(5): 101048, 2020 May 22.
Artigo
Inglês
| MEDLINE | ID: mdl-32335362
15.
Identifying Therapeutic Agents for Amelioration of Mitochondrial Clearance Disorder in Neurons of Familial Parkinson Disease.
Stem Cell Reports
; 14(6): 1060-1075, 2020 06 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32470327
16.
Reduced astrocytic reactivity in human brains and midbrain organoids with PRKN mutations.
NPJ Parkinsons Dis
; 6(1): 33, 2020 Nov 13.
Artigo
Inglês
| MEDLINE | ID: mdl-33298969
17.
Loss of nuclear REST/NRSF in aged-dopaminergic neurons in Parkinson's disease patients.
Neurosci Lett
; 699: 59-63, 2019 04 23.
Artigo
Inglês
| MEDLINE | ID: mdl-30684677
18.
Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson's disease.
Commun Biol
; 2: 424, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31799427
19.
Monitoring Mitochondrial Changes by Alteration of the PINK1-Parkin Signaling in Drosophila.
Methods Mol Biol
; 1759: 47-57, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-28324489
20.
Reduced TDP-43 Expression Improves Neuronal Activities in a Drosophila Model of Perry Syndrome.
EBioMedicine
; 21: 218-227, 2017 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-28625517