Pesquisa | Secretaria de Estado da Saúde

1.

Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2.

Klemm, Theresa; Ebert, Gregor; Calleja, Dale J; Allison, Cody C; Richardson, Lachlan W; Bernardini, Jonathan P; Lu, Bernadine Gc; Kuchel, Nathan W; Grohmann, Christoph; Shibata, Yuri; Gan, Zhong Yan; Cooney, James P; Doerflinger, Marcel; Au, Amanda E; Blackmore, Timothy R; van der Heden van Noort, Gerbrand J; Geurink, Paul P; Ovaa, Huib; Newman, Janet; Riboldi-Tunnicliffe, Alan; Czabotar, Peter E; Mitchell, Jeffrey P; Feltham, Rebecca; Lechtenberg, Bernhard C; Lowes, Kym N; Dewson, Grant; Pellegrini, Marc; Lessene, Guillaume; Komander, David.

EMBO J ; 39(18): e106275, 2020 09 15.

Artigo Inglês | MEDLINE | ID: mdl-32845033

2.

HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains.

Shibata, Yuri; Tokunaga, Fuminori; Goto, Eiji; Komatsu, Ginga; Gohda, Jin; Saeki, Yasushi; Tanaka, Keiji; Takahashi, Hirotaka; Sawasaki, Tatsuya; Inoue, Satoshi; Oshiumi, Hiroyuki; Seya, Tsukasa; Nakano, Hiroyasu; Tanaka, Yuetsu; Iwai, Kazuhiro; Inoue, Jun-Ichiro.

PLoS Pathog ; 13(1): e1006162, 2017 01.

Artigo Inglês | MEDLINE | ID: mdl-28103322

3.

The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response.

Sanada, Takahito; Kim, Minsoo; Mimuro, Hitomi; Suzuki, Masato; Ogawa, Michinaga; Oyama, Akiho; Ashida, Hiroshi; Kobayashi, Taira; Koyama, Tomohiro; Nagai, Shinya; Shibata, Yuri; Gohda, Jin; Inoue, Jun-ichiro; Mizushima, Tsunehiro; Sasakawa, Chihiro.

Nature ; 483(7391): 623-6, 2012 Mar 11.

Artigo Inglês | MEDLINE | ID: mdl-22407319

4.

Dominant negative OTULIN-related autoinflammatory syndrome.

Davidson, Sophia; Shibata, Yuri; Collard, Sophie; Zheng, Hongyu; Kong, Klara; Sun, June M; Laohamonthonkul, Pawat; Cerra, Anthony; Kratina, Tobias; Li, Margaret W Y; Russell, Carolyn; van Beek, Anna; Kirk, Edwin P; Walsh, Rebecca; Alqanatish, Jubran; Almojali, Abdullah; Alsuwairi, Wafaa; Alrasheed, Abdulrahman; Lalaoui, Najoua; Gray, Paul E; Komander, David; Masters, Seth L.

J Exp Med ; 221(6)2024 Jun 03.

Artigo Inglês | MEDLINE | ID: mdl-38630025

5.

LUBAC.

Shibata, Yuri; Komander, David.

Curr Biol ; 32(11): R506-R508, 2022 06 06.

Artigo Inglês | MEDLINE | ID: mdl-35671719

6.

Comparison of virological and serological methods for laboratory confirmation of rubella.

Uchino, Kiyoko; Miyoshi, Tatsuya; Mori, Yoshio; Komase, Katsuhiro; Okayama, Fumika; Shibata, Yuri; Yoshida, Hisayoshi; Numata, Tomizo; Takeda, Makoto; Tanaka, Tomoyuki.

J Clin Virol ; 123: 104257, 2020 02.

Artigo Inglês | MEDLINE | ID: mdl-31927348

7.

[A novel NF-kappaB regulatory mechanism targeting a polyubiquitin chain].

Shibata, Yuri; Inoue, Jun-Ichiro.

Seikagaku ; 85(6): 405-13, 2013 Jun.

Artigo Japonês | MEDLINE | ID: mdl-23875467

8.

A Dithiol Compound Binds to the Zinc Finger Protein TRAF6 and Suppresses Its Ubiquitination.

Koga, Ryoko; Radwan, Mohamed O; Ejima, Tomohiko; Kanemaru, Yosuke; Tateishi, Hiroshi; Ali, Taha F S; Ciftci, Halil Ibrahim; Shibata, Yuri; Taguchi, Yuu; Inoue, Jun-Ichiro; Otsuka, Masami; Fujita, Mikako.

ChemMedChem ; 12(23): 1935-1941, 2017 12 07.

Artigo Inglês | MEDLINE | ID: mdl-28884970

9.

Linear ubiquitin chains break blood vessel branches.

Shibata, Yuri; Komander, David.

Cell Res ; 31(10): 1045-1046, 2021 10.

Artigo Inglês | MEDLINE | ID: mdl-34429523

10.

Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity.

Sato, Yusuke; Goto, Eiji; Shibata, Yuri; Kubota, Yuji; Yamagata, Atsushi; Goto-Ito, Sakurako; Kubota, Keiko; Inoue, Jun-ichiro; Takekawa, Mutsuhiro; Tokunaga, Fuminori; Fukai, Shuya.

Nat Struct Mol Biol ; 22(3): 222-9, 2015 Mar.

Artigo Inglês | MEDLINE | ID: mdl-25686088

11.

p47 negatively regulates IKK activation by inducing the lysosomal degradation of polyubiquitinated NEMO.

Shibata, Yuri; Oyama, Masaaki; Kozuka-Hata, Hiroko; Han, Xiao; Tanaka, Yuetsu; Gohda, Jin; Inoue, Jun-ichiro.

Nat Commun ; 3: 1061, 2012.

Artigo Inglês | MEDLINE | ID: mdl-22990857

12.

Activation of the IκB kinase complex by HTLV-1 Tax requires cytosolic factors involved in Tax-induced polyubiquitination.

Shibata, Yuri; Tanaka, Yuetsu; Gohda, Jin; Inoue, Jun-ichiro.

J Biochem ; 150(6): 679-86, 2011 Dec.

Artigo Inglês | MEDLINE | ID: mdl-21862596

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