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J Popul Ther Clin Pharmacol ; 29(1): e116-e121, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35686903

RESUMO

BACKGROUND: Several investigations have confirmed changes in lipid profiles and other markers (interleukin [IL]-6, C-reactive protein [CRP]) in women with pregnancy induced hypertension (PIH). Although, the cause an effect correlations between these lipid profiles and other markers with the PIH are yet unknown. AIM: To study the relationship of serum lipid profile, CRP, and IL-6 with PIH. METHOD: A cross-sectional study was done on 60 pregnant women with PIH treated in the General Salah Alden Hospital in Tikrit city, Iraq, from January 2021 to April 2021. Another group of 60 pregnant women who were normal, at the same period, were selected as the control group. The average age of the participants was (27.1 ± 5.0) years. All the blood samples taken were examined for lipid profile, CRP, and IL-6. RESULTS: The results statistically showed significant differences in IL-6 level and CRP. Whereas, in the Lipid profile (triglyceride [TG], low density lipoprotein cholesterol [LDL-C], high density lipoprotein [HDL]-C, total cholesterol [TC], and very low density lipoprotein cholesterol [VLDL]) were found. Also, it was found that there were significant differences in PIH patients as compared to the control group. CONCLUSION: The findings revealed that the lipid profile was aberrant, and the amount of IL-6 protein was positively linked with blood pressure.


Assuntos
Dislipidemias , Hipertensão Induzida pela Gravidez , Adulto , Biomarcadores , HDL-Colesterol , Estudos Transversais , Dislipidemias/epidemiologia , Feminino , Humanos , Interleucina-6 , Gravidez , Adulto Jovem
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